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    Klra23 killer cell lectin-like receptor subfamily A, member 23 [ Mus musculus (house mouse) ]

    Gene ID: 79410, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Klra23provided by MGI
    Official Full Name
    killer cell lectin-like receptor subfamily A, member 23provided by MGI
    Primary source
    MGI:MGI:1930932
    See related
    AllianceGenome:MGI:1930932
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ly49W; Ly-49W1; Ly-49W2
    Summary
    Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    not in current annotation release
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    Genomic context

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    See Klra23 in Genome Data Viewer
    Location:
    6; 6 F3
    Annotation release Status Assembly Chr Location
    108.20200622 latest, but not current GRCm38.p6 (GCF_000001635.26) 6 Unlocalized Scaffold (NOD/ShiLtJ) NT_187002.1 (553984..576907, complement)

    Bibliography

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    Related articles in PubMed

    1. The activating Ly49W and inhibitory Ly49G NK cell receptors display similar affinities for identical MHC class I ligands. Ma BJ, et al. Immunogenetics, 2014 Aug. PMID 24797174
    2. Ly-49W, an activating receptor of nonobese diabetic mice with close homology to the inhibitory receptor Ly-49G, recognizes H-2D(k) and H-2D(d). Silver ET, et al. J Immunol, 2001 Feb 15. PMID 11160290
    3. Class I MHC-binding characteristics of the 129/J Ly49 repertoire. Makrigiannis AP, et al. J Immunol, 2001 Apr 15. PMID 11290784
    4. The ly49 gene family. A brief guide to the nomenclature, genetics, and role in intracellular infection. Schenkel AR, et al. Front Immunol, 2013. PMID 23596445, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The ectodomain of inhibitory Ly49G of the BALB/c mouse strain is highly similar to the Ly49W activating receptor in the nonobese diabetic (NOD) mouse.
      Title: The activating Ly49W and inhibitory Ly49G NK cell receptors display similar affinities for identical MHC class I ligands.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    killer cell lectin-like receptor subfamily A, member 23
    Names
    killer cell lectin-like receptor subfamily A, member 17

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024470.1 → NP_077790.1  killer cell lectin-like receptor subfamily A, member 23

      See identical proteins and their annotated locations for NP_077790.1

      Status: PROVISIONAL

      Source sequence(s)
      AF074459
      UniProtKB/TrEMBL
      Q9EP57, Q9EPB2
      Conserved Domains (2) summary
      cd03593
      Location:146 → 261
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:40 → 159
      Ly49; Ly49-like protein, N-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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