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    ymcE protein YmcE [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946951, updated on 17-Dec-2024

    Summary

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    Official Symbol
    ymcE
    Official Full Name
    protein YmcE
    Primary source
    ECOCYC:G6512
    Locus tag
    b0991
    See related
    ASAP:ABE-0003349
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0981
    Summary
    ymcE is transiently induced after a cold shock, dependent on the presence of PNPase. ymcE was misidentified as sfa in the Polissi et al. cold shock paper. [More information is available at EcoGene: EG13232]. YmcE was mistakenly thought to be a suppressor of fabA6, a temperature-sensitive unsaturated fatty acid auxotroph ; in fact, the suppressor localizes to the gnsA gene, which is located immediately downstream of ymcE . [More information is available at EcoCyc: G6512].
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    Genomic context

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    Sequence:
    NC_000913.3 (1051847..1052077)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene CspA family protein CspH Neighboring gene cold shock protein CspG Neighboring gene protein YmcF Neighboring gene putative phosphatidylethanolamine synthesis regulator GnsA Neighboring gene putative electron transport protein YccM Neighboring gene sensor histidine kinase TorS

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Increased unsaturated fatty acid production associated with a suppressor of the fabA6(Ts) mutation in Escherichia coli. Rock CO, et al. J Bacteriol, 1996 Sep. PMID 8808925, Free PMC Article
    2. Changes in Escherichia coli transcriptome during acclimatization at low temperature. Polissi A, et al. Res Microbiol, 2003 Oct. PMID 14527658
    3. Overexpression of yccL (gnsA) and ydfY (gnsB) increases levels of unsaturated fatty acids and suppresses both the temperature-sensitive fabA6 mutation and cold-sensitive secG null mutation of Escherichia coli. Sugai R, et al. J Bacteriol, 2001 Oct. PMID 11544213, Free PMC Article
    4. Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Lomize AL, et al. Nucleic Acids Res, 2017 Jan 4. PMID 27510400, Free PMC Article
    5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein YmcE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1051847..1052077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415511.1 protein YmcE [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415511.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A192CLD8, A0AA36KWB3, Q1RDM8
      Conserved Domains (1) summary
      pfam15939
      Location:1 → 76
      YmcE_antitoxin; Putative antitoxin of bacterial toxin-antitoxin system
    Nucleotide Protein
    Heading Accession and Version

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