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    Saposin-like aspartyl protease family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825776, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Saposin-like aspartyl protease family protein
    Primary source
    TAIR:AT4G04460
    Locus tag
    AT4G04460
    See related
    Araport:AT4G04460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T26N6.7; T26N6_7
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    13
    Sequence:
    Chromosome: 4; NC_003075.7 (2224422..2227874)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene WRKY family transcription factor Neighboring gene Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein Neighboring gene F-box protein with a domain protein Neighboring gene cysteine-rich RLK (RECEPTOR-like protein kinase) 36

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Leaf proteome responses of Arabidopsis thaliana exposed to mild cadmium stress. Semane B, et al. J Plant Physiol, 2010 Mar 1. PMID 20005002
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001203742.1
    NM_116684.4

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Saposin-like aspartyl protease family protein
    NP_001190671.1
    • Saposin-like aspartyl protease family protein; FUNCTIONS IN: aspartic-type endopeptidase activity; INVOLVED IN: response to cadmium ion, proteolysis; LOCATED IN: endomembrane system; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Saposin-like (InterPro:IPR011001), Peptidase aspartic, catalytic (InterPro:IPR009007), Peptidase aspartic (InterPro:IPR021109), Saposin-like type B, 1 (InterPro:IPR007856), Saposin-like type B, 2 (InterPro:IPR008138), Saposin B (InterPro:IPR008139), Peptidase A1 (InterPro:IPR001461), Peptidase aspartic, active site (InterPro:IPR001969); BEST Arabidopsis thaliana protein match is: aspartic proteinase A1 (TAIR:AT1G11910.1).
    NP_192355.1
    • Saposin-like aspartyl protease family protein; FUNCTIONS IN: aspartic-type endopeptidase activity; INVOLVED IN: response to cadmium ion, proteolysis; LOCATED IN: endomembrane system; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Saposin-like (InterPro:IPR011001), Peptidase aspartic (InterPro:IPR021109), Peptidase aspartic, catalytic (InterPro:IPR009007), Saposin-like type B, 1 (InterPro:IPR007856), Saposin-like type B, 2 (InterPro:IPR008138), Saposin B (InterPro:IPR008139), Peptidase A1 (InterPro:IPR001461), Peptidase aspartic, active site (InterPro:IPR001969); BEST Arabidopsis thaliana protein match is: aspartic proteinase A1 (TAIR:AT1G11910.1); Has 6789 Blast hits to 4881 proteins in 419 species: Archae - 0; Bacteria - 8; Metazoa - 3731; Fungi - 1673; Plants - 537; Viruses - 0; Other Eukaryotes - 840 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      2224422..2227874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203742.1 → NP_001190671.1  Saposin-like aspartyl protease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190671.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V6K3, A0A5S9XPZ8, A0A7G2EW99, F4JGD2
      Conserved Domains (5) summary
      cd06098
      Location:77 → 502
      phytepsin; Phytepsin, a plant homolog of mammalian lysosomal pepsins
      smart00741
      Location:316 → 349
      SapB; Saposin (B) Domains
      pfam00026
      Location:86 → 503
      Asp; Eukaryotic aspartyl protease
      pfam03489
      Location:322 → 349
      SapB_2; Saposin-like type B, region 2
      pfam05184
      Location:378 → 412
      SapB_1; Saposin-like type B, region 1

    2. NM_116684.4 → NP_192355.1  Saposin-like aspartyl protease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192355.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XEC4
      UniProtKB/TrEMBL
      A0A178V6K3, A0A5S9XPZ8, A0A654FLW7, A0A7G2EW99
      Conserved Domains (3) summary
      cd06098
      Location:77 → 506
      phytepsin; Phytepsin, a plant homolog of mammalian lysosomal pepsins
      pfam03489
      Location:321 → 353
      SapB_2; Saposin-like type B, region 2
      pfam05184
      Location:382 → 417
      SapB_1; Saposin-like type B, region 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XEC4.1

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