U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein Clusters

    • Showing Current items.

    AFP2 ABI five binding protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837934, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    AFP2
    Official Full Name
    ABI five binding protein 2
    Primary source
    TAIR:AT1G13740
    Locus tag
    AT1G13740
    See related
    Araport:AT1G13740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABI five binding protein 2; F21F23.17; F21F23_17
    Summary
    Encodes a member of a small plant-specific gene family whose members interact with ABI5 and appear to be involved in mediating stress responses. AFP2 mutants affect a number of ABA mediated processes such as germination and response to osmotic and sugar stress. AFP2 nuclear localization is stress dependent.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See AFP2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (4713433..4715407)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene tRNA-Thr Neighboring gene Nuclear transport factor 2 (NTF2) family protein with RNA binding (RRM-RBD-RNP motifs) domain-containing protein Neighboring gene ncRNA Neighboring gene Purple acid phosphatases superfamily protein Neighboring gene Defensin-like (DEFL) family protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A small plant-specific protein family of ABI five binding proteins (AFPs) regulates stress response in germinating Arabidopsis seeds and seedlings. Garcia ME, et al. Plant Mol Biol, 2008 Aug. PMID 18484180
    2. SOS2-AFP2 module regulates seed germination by inducing ABI5 degradation in response to salt stress in Arabidopsis. Wang C, et al. Biochem Biophys Res Commun, 2024 Sep 3. PMID 38838447
    3. ABI5-BINDING PROTEIN2 Coordinates CONSTANS to Delay Flowering by Recruiting the Transcriptional Corepressor TPR2. Chang G, et al. Plant Physiol, 2019 Feb. PMID 30514725, Free PMC Article
    4. ABI5-binding proteins (AFPs) alter transcription of ABA-induced genes via a variety of interactions with chromatin modifiers. Lynch TJ, et al. Plant Mol Biol, 2017 Mar. PMID 27942958
    5. AFP2 as the novel regulator breaks high-temperature-induced seeds secondary dormancy through ABI5 and SOM in Arabidopsis thaliana. Chang G, et al. Biochem Biophys Res Commun, 2018 Jun 18. PMID 29723526

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SOS2-AFP2 module regulates seed germination by inducing ABI5 degradation in response to salt stress in Arabidopsis.
      Title: SOS2-AFP2 module regulates seed germination by inducing ABI5 degradation in response to salt stress in Arabidopsis.
    2. AFP2 recruits the corepressor TPR2 to coordinate the CO protein signal and thereby ensure that flowering occurs at an appropriate time.
      Title: ABI5-BINDING PROTEIN2 Coordinates CONSTANS to Delay Flowering by Recruiting the Transcriptional Corepressor TPR2.
    3. SOM is reported to negatively regulate seeds germination by altering GA/ABA metabolism, here we found that AFP2 and ABI5 altered SOM transcription. Data demonstrate that AFP2 is a novel regulator to control high temperature-induced secondary seed dormancy through ABI5 and SOM.
      Title: AFP2 as the novel regulator breaks high-temperature-induced seeds secondary dormancy through ABI5 and SOM in Arabidopsis thaliana.
    4. Results suggest that the ABI5/ABF binding proteins (AFPs) AFP1 and AFP2 participate in multiple mechanisms modulating abscisic Acid (ABA) response.
      Title: ABI5-binding proteins (AFPs) alter transcription of ABA-induced genes via a variety of interactions with chromatin modifiers.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_101242.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ABI five binding protein 2
    NP_563933.1
    • ABI five binding protein 2 (AFP2); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1675 (InterPro:IPR012463); BEST Arabidopsis thaliana protein match is: ABI five binding protein (TAIR:AT1G69260.1); Has 207 Blast hits to 201 proteins in 26 species: Archae - 0; Bacteria - 0; Metazoa - 5; Fungi - 6; Plants - 185; Viruses - 3; Other Eukaryotes - 8 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4713433..4715407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101242.3 → NP_563933.1  ABI five binding protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563933.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93ZQ8, Q9LMX5
      UniProtKB/TrEMBL
      A0A178WBB1, A0A5S9U9Q2
      Conserved Domains (3) summary
      pfam07897
      Location:54 → 88
      EAR; Ethylene-responsive binding factor-associated repression
      pfam16135
      Location:309 → 339
      Jas; TPL-binding domain in jasmonate signalling
      pfam16136
      Location:107 → 181
      NINJA_B; Putative nuclear localization signal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LMX5.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools