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    repo-1 Matrin-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178147, updated on 9-Dec-2024

    Summary

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    Official Symbol
    repo-1
    Official Full Name
    Matrin-type domain-containing protein
    Primary source
    WormBase:WBGene00008683
    Locus tag
    CELE_F11A10.2
    See related
    AllianceGenome:WB:WBGene00008683
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to be involved in spliceosomal complex assembly. Predicted to be located in nucleus. Predicted to be part of U2 snRNP; U2-type prespliceosome; and catalytic step 2 spliceosome. Is expressed in several structures, including body wall musculature; enteric muscle; hypodermis; nervous system; and vulval muscle. Orthologous to human SF3A2 (splicing factor 3a subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See repo-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_003282.8 (12084478..12085320)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene GOLD domain-containing protein Neighboring gene Tat-binding homolog 7 Neighboring gene RRM domain-containing protein Neighboring gene ncRNA Neighboring gene Transmembrane protein 115

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription factors regulating the fate and developmental potential of a multipotent progenitor in Caenorhabditis elegans. Soukup EM, et al. G3 (Bethesda), 2022 Nov 4. PMID 36063055, Free PMC Article
    2. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Meissner B, et al. PLoS Genet, 2009 Jun. PMID 19557190, Free PMC Article
    3. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article
    4. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    5. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spliceosomal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Matrin-type domain-containing protein
    NP_502290.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12084478..12085320
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069889.7 → NP_502290.1  Matrin-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502290.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19335
      Conserved Domains (1) summary
      COG5246
      Location:1 → 213
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
    Nucleotide Protein
    Heading Accession and Version

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