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    Dup99B Ductus ejaculatorius peptide 99B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 2768691, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dup99Bprovided by FlyBase
    Official Full Name
    Ductus ejaculatorius peptide 99Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0250832
    Locus tag
    Dmel_CG33495
    See related
    AllianceGenome:FB:FBgn0250832
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-SAGE:Wang-013; CG33495; Dmel\CG33495; DUP; DUP99b; DUP99B
    Summary
    Enables G protein-coupled receptor binding activity. Involved in G protein-coupled receptor signaling pathway; egg-laying behavior; and negative regulation of female receptivity, post-mating. Located in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Dup99B in Genome Data Viewer
    Location:
    99B8-99B8; 3-99 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29715068..29715377, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25540790..25541099, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45569 Neighboring gene Odorant-binding protein 99d Neighboring gene Odorant-binding protein 99b Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46108

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ductus ejaculatorius peptide 99B (DUP99B), a novel Drosophila melanogaster sex-peptide pheromone. Saudan P, et al. Eur J Biochem, 2002 Feb. PMID 11846801
    2. Binding sites of Drosophila melanogaster sex peptide pheromones. Ottiger M, et al. J Neurobiol, 2000 Jul. PMID 10880132
    3. Common functional elements of Drosophila melanogaster seminal peptides involved in reproduction of Drosophila melanogaster and Helicoverpa armigera females. Fan Y, et al. Insect Biochem Mol Biol, 2000 Aug-Sep. PMID 10876124
    4. The evolution of sex peptide: sexual conflict, cooperation, and coevolution. Hopkins BR, et al. Biol Rev Camb Philos Soc, 2022 Aug. PMID 35249265, Free PMC Article
    5. Sex-peptides bind to two molecularly different targets in Drosophila melanogaster females. Ding Z, et al. J Neurobiol, 2003 Jun. PMID 12717705

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in egg-laying behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of female receptivity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in negative regulation of female receptivity, post-mating IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of egg-laying behavior TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of female receptivity, post-mating IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sexual reproduction HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular space HDA PubMed 

    General protein information

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    Preferred Names
    ductus ejaculatorius peptide 99B
    Names
    CG33495-PA
    CG33495-PB
    Dup99B-PA
    Dup99B-PB
    anon-SAGE:Wang-013

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29715068..29715377 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206582.2 → NP_996305.1  ductus ejaculatorius peptide 99B, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996305.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3DMS6, P81160
      UniProtKB/TrEMBL
      D1Z366
      Conserved Domains (1) summary
      pfam08138
      Location:30 → 52
      Sex_peptide; Sex peptide (SP) family

    2. NM_001260430.1 → NP_001247359.1  ductus ejaculatorius peptide 99B, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247359.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K801
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K801 A0A0B4K801
    P81160.2 P81160

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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