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    CIBAR2 CBY1 interacting BAR domain containing 2 [ Homo sapiens (human) ]

    Gene ID: 339145, updated on 3-Dec-2024

    Summary

    Official Symbol
    CIBAR2provided by HGNC
    Official Full Name
    CBY1 interacting BAR domain containing 2provided by HGNC
    Primary source
    HGNC:HGNC:24781
    See related
    Ensembl:ENSG00000153789 MIM:617274; AllianceGenome:HGNC:24781
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM92B
    Summary
    Predicted to be involved in cilium assembly. Predicted to be located in cell projection; centriole; and cytoplasm. Predicted to be active in ciliary basal body and ciliary transition zone. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in lung (RPKM 3.3), endometrium (RPKM 0.5) and 4 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CIBAR2 in Genome Data Viewer
    Location:
    16q24.1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (85098358..85112472, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (91164997..91179113, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (85131964..85146078, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr16:85009937-85011136 Neighboring gene zinc finger DHHC-type palmitoyltransferase 7 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85028227-85028727 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85038209-85038959 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7796 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:85045288-85046044 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11257 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7797 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7798 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11258 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85068709-85069209 Neighboring gene KIAA0513 Neighboring gene Sharpr-MPRA regulatory region 15308 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85100891-85101391 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85110035-85110590 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11259 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85111701-85112255 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85115357-85116184 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85116185-85117012 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85117013-85117838 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7799 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85121851-85122676 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85124326-85125149 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11260 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11261 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11262 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11263 Neighboring gene uncharacterized LOC105371381 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85159272-85159794 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85159795-85160316 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:85170709-85171641 Neighboring gene uncharacterized LOC105371382 Neighboring gene long intergenic non-protein coding RNA 2139 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85180218-85180762 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:85180763-85181307

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ44299, MGC138149

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in ciliary transition zone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    CBY1-interacting BAR domain-containing protein 2
    Names
    family with sequence similarity 92 member B
    protein FAM92B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001366920.1NP_001353849.1  CBY1-interacting BAR domain-containing protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC026469
      UniProtKB/Swiss-Prot
      A0A0D9SG36, Q6ZTR7
    2. NM_198491.3NP_940893.1  CBY1-interacting BAR domain-containing protein 2 isoform 1

      See identical proteins and their annotated locations for NP_940893.1

      Status: VALIDATED

      Source sequence(s)
      AC026469, AK126284, BU680724
      Consensus CDS
      CCDS32500.1
      UniProtKB/Swiss-Prot
      A0A0D9SG36, Q6ZTR7
      UniProtKB/TrEMBL
      A0A1X7SC74
      Related
      ENSP00000443411.1, ENST00000539556.6
      Conserved Domains (1) summary
      cd07598
      Location:6216
      BAR_FAM92; The Bin/Amphiphysin/Rvs (BAR) domain of Family with sequence similarity 92 (FAM92)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      85098358..85112472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017023198.2XP_016878687.1  CBY1-interacting BAR domain-containing protein 2 isoform X2

      UniProtKB/Swiss-Prot
      A0A0D9SG36, Q6ZTR7
    2. XM_011523063.2XP_011521365.1  CBY1-interacting BAR domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011521365.1

      UniProtKB/Swiss-Prot
      A0A0D9SG36, Q6ZTR7
      UniProtKB/TrEMBL
      A0A1X7SC74
      Conserved Domains (1) summary
      cd07598
      Location:6216
      BAR_FAM92; The Bin/Amphiphysin/Rvs (BAR) domain of Family with sequence similarity 92 (FAM92)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      91164997..91179113 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054380216.1XP_054236191.1  CBY1-interacting BAR domain-containing protein 2 isoform X2

      UniProtKB/Swiss-Prot
      A0A0D9SG36, Q6ZTR7
    2. XM_054380215.1XP_054236190.1  CBY1-interacting BAR domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      A0A0D9SG36, Q6ZTR7
      UniProtKB/TrEMBL
      A0A1X7SC74