| Long-chain noncoding RNA LINC01569 upregulates filamin A-interacting protein 1-like to prevent metastasis of triple-negative breast cancer via sponging miR-300. | Long-chain noncoding RNA LINC01569 upregulates filamin A-interacting protein 1-like to prevent metastasis of triple-negative breast cancer via sponging miR-300.
Jiang X, Lin J, Zhu Z., Free PMC Article | 03/13/2024 |
| Has-miR-300-GADD45B promotes melanoma growth via cell cycle. | Has-miR-300-GADD45B promotes melanoma growth via cell cycle.
Chen L, Fang C, Yuan X, Liu M, Wu P, Zhong L, Chen Z., Free PMC Article | 12/28/2023 |
| Expression Levels of MicroRNA-300/BCL2L11 in Papillary Thyroid Cancer and Their Clinical Diagnostic Values. | Expression Levels of MicroRNA-300/BCL2L11 in Papillary Thyroid Cancer and Their Clinical Diagnostic Values.
Shen Y, Li X, Xie R, Chen Y, Hu X, Liu Y, Ma H. | 09/7/2023 |
| MiR-300 promotes the proliferation, migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis by targeting IL-37. | MiR-300 promotes the proliferation, migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis by targeting IL-37.
Wang Y, Zhang G, Huang W. | 08/13/2022 |
| Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions. | Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions.
Silvestri G, Trotta R, Stramucci L, Ellis JJ, Harb JG, Neviani P, Wang S, Eisfeld AK, Walker CJ, Zhang B, Srutova K, Gambacorti-Passerini C, Pineda G, Jamieson CHM, Stagno F, Vigneri P, Nteliopoulos G, May PC, Reid AG, Garzon R, Roy DC, Moutuou MM, Guimond M, Hokland P, Deininger MW, Fitzgerald G, Harman C, Dazzi F, Milojkovic D, Apperley JF, Marcucci G, Qi J, Polakova KM, Zou Y, Fan X, Baer MR, Calabretta B, Perrotti D., Free PMC Article | 03/19/2022 |
| Inhibition of microRNA-300 inhibits cell adhesion, migration, and invasion of prostate cancer cells by promoting the expression of DAB1. | Inhibition of microRNA-300 inhibits cell adhesion, migration, and invasion of prostate cancer cells by promoting the expression of DAB1.
Li L, Hao J, Yan CQ, Wang HF, Meng B, Cai SY., Free PMC Article | 12/11/2021 |
| UBE2C mRNA expression controlled by miR-300 and HuR determines its oncogenic role in gastric cancer. | UBE2C mRNA expression controlled by miR-300 and HuR determines its oncogenic role in gastric cancer.
Wang Y, Huang F, Liu M, Zhao Q. | 04/24/2021 |
| LINC00472 promotes osteogenic differentiation and alleviates osteoporosis by sponging miR-300 to upregulate the expression of FGFR2. | LINC00472 promotes osteogenic differentiation and alleviates osteoporosis by sponging miR-300 to upregulate the expression of FGFR2.
Guo HL, Wang X, Yang GY, Wu YY, Chen YC, Zhan HS, Zhao YF. | 04/24/2021 |
| [MiR-300 inhibits invasion and metastasis of osteosarcoma cell MG63 by negatively regulating PTTG1]. | [MiR-300 inhibits invasion and metastasis of osteosarcoma cell MG63 by negatively regulating PTTG1].
Liang D, Wu X, Bai J, Zhang L, Yin C, Zhong W., Free PMC Article | 02/27/2021 |
| MiRNA-300 suppresses proliferation, migration and invasion of non-small cell lung cancer via targeting ETS1. | MiRNA-300 suppresses proliferation, migration and invasion of non-small cell lung cancer via targeting ETS1.
Yang YB, Tan H, Wang Q. | 12/19/2020 |
| Serum ROCK2, miR-300 and miR-450b-5p levels in two different clinical phenotypes of multiple sclerosis: Relation to patient disability and disease progression. | Serum ROCK2, miR-300 and miR-450b-5p levels in two different clinical phenotypes of multiple sclerosis: Relation to patient disability and disease progression.
Ibrahim SH, El-Mehdawy KM, Seleem M, El-Sawalhi MM, Shaheen AA. | 12/12/2020 |
| LncRNA DLEU1/microRNA-300/RAB22A axis regulates migration and invasion of breast cancer cells. | LncRNA DLEU1/microRNA-300/RAB22A axis regulates migration and invasion of breast cancer cells.
Wang C, Xie XX, Li WJ, Jiang DQ. | 10/24/2020 |
| miR-300 directly targeted SP1 and suppressed its expression by specifically binding to its 3'-untranslated region. Small interference RNAs silencing SP1 phenocopied the effects of miR-300 overexpression, while restoration of SP1 expression partially rescued the inhibition of metastasis induced by miR-300 overexpression. | MIR-300 in the imprinted DLK1-DIO3 domain suppresses the migration of bladder cancer by regulating the SP1/MMP9 pathway.
Yan H, Li J, Ying Y, Xie H, Chen H, Xu X, Zheng X., Free PMC Article | 11/16/2019 |
| Serum level of miR-300 and tumor necrosis factor-alpha (TNFalpha) was increased in the knee osteoarthritis (KOA) patients. | MiR-300 Serves as Potential Biomarker to Screen Knee Osteoarthritis Patients by Targeting TNFα.
Zhou Z, Tian F, An N, Zhang Y, Wang C, Guo L. | 09/21/2019 |
| Study revealed that miR300 expression was significantly decreased in hepatocellular carcinoma (HCC) cell lines compared with normal liver cells. LEF1 which was verified as a direct target gene of miR300, promoted cell proliferation, migration and invasion and mediates the effects of miR300. Low expression of miR300 and high expression of LEF1 in HCC tissues is associated with poor prognosis of patients with HCC. | miR‑300 regulates tumor proliferation and metastasis by targeting lymphoid enhancer‑binding factor 1 in hepatocellular carcinoma.
Chen Y, Guo Y, Li Y, Yang J, Liu J, Wu Q, Wang R., Free PMC Article | 08/31/2019 |
| MicroRNA-300 is a tumor suppressor microRNA in non-small cell lung cancer by downregulating HIF3alpha expression. | MicroRNA-300 targets hypoxia inducible factor-3 alpha to inhibit tumorigenesis of human non-small cell lung cancer.
Zhang Y, Guo Y, Yang C, Zhang S, Zhu X, Cao L, Nie W, Yu H. | 04/27/2019 |
| Study shows that miR300 expression is increased in hepatocellular carcinoma (HCC) cell lines and tissues and associated with increased risk for invasiveness and relapse. Data revealed that miRNA300 functions as an oncogene in liver cancer by inhibiting FOXO1 and interacting with the AKT/mTOR signaling pathway. | Upregulation of microRNA‑300 induces the proliferation of liver cancer by downregulating transcription factor FOXO1.
Chang Y, Zhou C, Fan L, Qiu G, Wang G, Wei G, Chang X, Li X. | 12/22/2018 |
| miR-300 targeting modulates FAK, and the PI3K/AKT signaling pathway inhibits the epithelial-mesenchymal transition and suppresses the migration and invasion of hepatocellular carcinoma cells. | miR-300 regulates the epithelial-mesenchymal transition and invasion of hepatocellular carcinoma by targeting the FAK/PI3K/AKT signaling pathway.
Wang R, Yu Z, Chen F, Xu H, Shen S, Chen W, Chen L, Su Q, Zhang L, Bi J, Zeng W, Li W, Huang X, Wang Q. | 10/13/2018 |
| we first identified that the level of miR-300 was significantly upregulated in the blood samples of acute lung injury patients compared with healthy control | Increased serum miR-300 level serves as a potential biomarker of lipopolysaccharide-induced lung injury by targeting IκBα.
Cao W, Dai H, Yang S, Liu Z, Yi Chen Q. | 08/25/2018 |
| miR-300 regulates the cellular sensitivity to ionizing radiation through targeting p53 and apaf1 in lung cancer cells. | miR-300 regulates cellular radiosensitivity through targeting p53 and apaf1 in human lung cancer cells.
He J, Feng X, Hua J, Wei L, Lu Z, Wei W, Cai H, Wang B, Shi W, Ding N, Li H, Zhang Y, Wang J., Free PMC Article | 06/2/2018 |
| Twist1 was demonstrated to act as a direct target of miR300, and was negatively regulated by miR300. In addition, miR300 overexpression downregulated the expression of the primary factors involved in the NFkappaB signaling pathway. | MicroRNA-300 decreases cell viability, inhibits migration and promotes apoptosis of osteosarcoma cells via downregulation of Twist1.
Jia J, Yin P, Han G, Xu M, Wang W, Bi W. | 04/28/2018 |
| Data show that ROCK1 is the direct target of miR-300, and that the 3' UTRs of ROCK1 had at least 7 nucleotides that were complementary to the miR-300 seed region. | MicroRNA-300 inhibited glioblastoma progression through ROCK1.
Zhou F, Li Y, Hao Z, Liu X, Chen L, Cao Y, Liang Z, Yuan F, Liu J, Wang J, Zheng Y, Dong D, Bian S, Yang B, Jiang C, Li Q., Free PMC Article | 12/30/2017 |
| miR-300 promoted proliferation and epithelial-mesenchymal transition-mediated colorectal cancer cell migration and invasion by targeting p53. | miR-300 promotes proliferation and EMT-mediated colorectal cancer migration and invasion by targeting p53.
Wang L, Yu P. | 03/25/2017 |
| LncRNA TUG1 promotes gallbladder carcinoma cell proliferation, metastasis and epithelial-mesenchymal transition progression by functioning as a miRNA sponge to abrogate the endogenous effect of miR-300. | Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma.
Ma F, Wang SH, Cai Q, Jin LY, Zhou D, Ding J, Quan ZW. | 03/18/2017 |
| Data show that microRNA miR-300 directly represses vascular endothelial growth factor-C (VEGF-C) expression via binding to the 3' untranslated regions (3'-UTR) of VEGF-C. | WISP-1 promotes VEGF-C-dependent lymphangiogenesis by inhibiting miR-300 in human oral squamous cell carcinoma cells.
Lin CC, Chen PC, Lein MY, Tsao CW, Huang CC, Wang SW, Tang CH, Tung KC., Free PMC Article | 01/28/2017 |