| Downregulation of lncRNA NEAT1 interacts with miR-374b-5p/PGAP1 axis to aggravate the development of osteoarthritis. | Downregulation of lncRNA NEAT1 interacts with miR-374b-5p/PGAP1 axis to aggravate the development of osteoarthritis.
Huang F, Su Z, Yang J, Zhao X, Xu Y., Free PMC Article | 09/28/2023 |
| MAGI2-AS3 and miR-374b-5p as Putative Regulators of Multiple Sclerosis via Modulating the PTEN/AKT/IRF-3/IFN-beta Axis: New Clinical Insights. | MAGI2-AS3 and miR-374b-5p as Putative Regulators of Multiple Sclerosis via Modulating the PTEN/AKT/IRF-3/IFN-β Axis: New Clinical Insights.
Kortam MA, Elfar N, Shaker OG, El-Boghdady NA, Abd-Elmawla MA. | 03/21/2023 |
| MiRNA-374b-5p and miRNA-106a-5p are related to inflammatory bowel disease via regulating IL-10 and STAT3 signaling pathways. | MiRNA-374b-5p and miRNA-106a-5p are related to inflammatory bowel disease via regulating IL-10 and STAT3 signaling pathways.
Li D, Liu L, Du X, Ma W, Zhang J, Piao W., Free PMC Article | 12/10/2022 |
| The role of circulating blood microRNA-374 and microRNA-10 levels in the pathogenesis and therapeutic mechanisms of major depressive disorder. | The role of circulating blood microRNA-374 and microRNA-10 levels in the pathogenesis and therapeutic mechanisms of major depressive disorder.
Liu W, Zhang F, Zheng Y, He S, Zhang T, Guo Q, Xu H, Chen H, Liu C, Yu S, Jiang K, Li H, Li G, Wang X, Liu X. | 02/5/2022 |
| hsa-miR-374b-5p regulates expression of the gene U2AF homology motif (UHM) kinase 1. | hsa-miR-374b-5p regulates expression of the gene U2AF homology motif (UHM) kinase 1.
Mueller R, Bajric D, Keceli HG, Keller A, Dommisch H, Elsharawy A, Schaefer AS. | 12/11/2021 |
| MicroRNA-374b inhibits breast cancer progression through regulating CCND1 and TGFA genes. | MicroRNA-374b inhibits breast cancer progression through regulating CCND1 and TGFA genes.
Liu Y, Zhang A, Bao PP, Lin L, Wang Y, Wu H, Shu XO, Liu A, Cai Q., Free PMC Article | 10/2/2021 |
| miR-374b-5p is increased in deep vein thrombosis and negatively targets IL-10. | miR-374b-5p is increased in deep vein thrombosis and negatively targets IL-10.
Zhang Y, Miao X, Zhang Z, Wei R, Sun S, Liang G, Li H, Chu C, Zhao L, Zhu X, Guo Q, Wang B, Li X. | 07/17/2021 |
| MicroRNA-374b mediates the initiation of non-small cell lung cancer by regulating ITGB1 and p53 expressions. | MicroRNA-374b mediates the initiation of non-small cell lung cancer by regulating ITGB1 and p53 expressions.
Zhao M, Tong C, Hao Z, Zhao R, Wang L., Free PMC Article | 03/20/2021 |
| Differential microRNAs expression in seminal plasma of normospermic patients with different sperm DNA fragmentation indexes. | Differential microRNAs expression in seminal plasma of normospermic patients with different sperm DNA fragmentation indexes.
Li L, Li H, Tian Y, Hu M, Le F, Wang L, Liu X, Jin F. | 02/27/2021 |
| ABCA8 is regulated by miR-374b-5p and inhibits proliferation and metastasis of hepatocellular carcinoma through the ERK/ZEB1 pathway. | ABCA8 is regulated by miR-374b-5p and inhibits proliferation and metastasis of hepatocellular carcinoma through the ERK/ZEB1 pathway.
Cui Y, Liang S, Zhang S, Zhang C, Zhao Y, Wu D, Wang J, Song R, Wang J, Yin D, Liu Y, Pan S, Liu X, Wang Y, Han J, Meng F, Zhang B, Guo H, Lu Z, Liu L., Free PMC Article | 02/6/2021 |
| Diagnostic Value of Peripheral Blood miR-374b-5p in Patients with Prostate Cancer. | Diagnostic Value of Peripheral Blood miR-374b-5p in Patients with Prostate Cancer.
Pang C, Song X, Fu C, Zhang Y, Zhang Y, Liu M. | 11/21/2020 |
| Circulating miR-374b-5p negatively regulates osteoblast differentiation in the progression of osteoporosis via targeting Wnt3 AND Runx2. | Circulating miR-374b-5p negatively regulates osteoblast differentiation in the progression of osteoporosis via targeting Wnt3 AND Runx2.
Xu Y, Zhang S, Fu D, Lu D. | 09/5/2020 |
| MiR-374b reduces cell proliferation and cell invasion of cervical cancer through regulating FOXM1. | MiR-374b reduces cell proliferation and cell invasion of cervical cancer through regulating FOXM1.
Xia N, Tan WF, Peng QZ, Cai HN. | 08/15/2020 |
| a functional MAGI2-AS3/miR-374b-5p/SMG1 axis that suppresses hepatocellular cancer progression, is reported. | LncRNA MAGI2-AS3 inhibits hepatocellular carcinoma cell proliferation and migration by targeting the miR-374b-5p/SMG1 signaling pathway.
Yin Z, Ma T, Yan J, Shi N, Zhang C, Lu X, Hou B, Jian Z. | 05/30/2020 |
| iR-374b significantly inhibits cell proliferation, migration, and invasion through the blockade of the p38/ERK signaling pathway activation, as well as negatively binding to JAM-2 | MicroRNA-374b inhibits cervical cancer cell proliferation and induces apoptosis through the p38/ERK signaling pathway by binding to JAM-2.
Li GC, Cao XY, Li YN, Qiu YY, Li YN, Liu XJ, Sun XX. | 10/5/2019 |
| miR-454-3p and miR-374b-5p negatively regulated invasion and migration of Bladder cancer cell lines via targeting ZEB2. | MiR-454-3p and miR-374b-5p suppress migration and invasion of bladder cancer cells through targetting ZEB2.
Wang S, Zhang G, Zheng W, Xue Q, Wei D, Zheng Y, Yuan J., Free PMC Article | 08/3/2019 |
| miR-374b-5p-FOXP1 feedback loop regulates tumor progression in ovarian cancer. | MiR-374b-5p-FOXP1 feedback loop regulates cell migration, epithelial-mesenchymal transition and chemosensitivity in ovarian cancer.
Li H, Liang J, Qin F, Zhai Y. | 05/11/2019 |
| Results showed that MiR-374b was highly expressed, while PTEN was downregulated in the GIST tissues. The levels of miR-374b, PI3K, AKT and PTEN were related to tumor diameter and pathological stage. Additionally, miR-374b increased the mRNA and protein levels of PI3K, Akt, MMP2, MMP9, P53 and cyclinD1, suggesting that miR-374b activates PI3K/Akt signaling pathway in GIST-T1 cells. | MiR-374b Promotes Proliferation and Inhibits Apoptosis of Human GIST Cells by Inhibiting PTEN through Activation of the PI3K/Akt Pathway.
Long ZW, Wu JH, Cai-Hong, Wang YN, Zhou Y., Free PMC Article | 11/17/2018 |
| we identified downregulation of miR-374b as likely being directly involved in acquisition of the drug-resistant phenotype. | Evidence for the role of microRNA 374b in acquired cisplatin resistance in pancreatic cancer cells.
Schreiber R, Mezencev R, Matyunina LV, McDonald JF., Free PMC Article | 01/13/2018 |
| Findings showed that miR-374b expression was significantly downregulated in colon cancer tissues and cell lines and suggest that miR-374b inhibits colon cancer cell proliferation and invasion through downregulation of LRH-1 expression. | MicroRNA-374b reduces the proliferation and invasion of colon cancer cells by regulation of LRH-1/Wnt signaling.
Qu R, Hao S, Jin X, Shi G, Yu Q, Tong X, Guo D. | 12/30/2017 |
| It is a potential biomarker for amyotrophic lateral sclerosis. | Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS).
Waller R, Goodall EF, Milo M, Cooper-Knock J, Da Costa M, Hobson E, Kazoka M, Wollff H, Heath PR, Shaw PJ, Kirby J., Free PMC Article | 12/2/2017 |
| Moreover, inhibition on miR-374b relieved the suppressed AKT1 protein, and reduced cell apoptosis induced by BLM. These data depict the p53/miR-374b/AKT1 signaling that may regulate BLM-induced apoptosis in Colorectal cancer (CRC)cells, thus facilitating to improve the outcome of chemotherapy in CRC. | p53/microRNA-374b/AKT1 regulates colorectal cancer cell apoptosis in response to DNA damage.
Gong H, Cao Y, Han G, Zhang Y, You Q, Wang Y, Pan Y. | 07/22/2017 |
| MicroRNA-374b Suppresses Proliferation and Promotes Apoptosis in T-cell Lymphoblastic Lymphoma by Repressing AKT1 and Wnt-16 | MicroRNA-374b Suppresses Proliferation and Promotes Apoptosis in T-cell Lymphoblastic Lymphoma by Repressing AKT1 and Wnt-16.
Qian D, Chen K, Deng H, Rao H, Huang H, Liao Y, Sun X, Lu S, Yuan Z, Xie D, Cai Q. | 08/20/2016 |
| Report potential value of miR-1 and miR-374b as biomarkers for colorectal cancer at different stages. | The potential value of miR-1 and miR-374b as biomarkers for colorectal cancer.
Wu X, Li S, Xu X, Wu S, Chen R, Jiang Q, Li Y, Xu Y., Free PMC Article | 03/12/2016 |
| Suggest that upregulation of miR-374b-5p contributes to gastric cancer cell metastasis and invasion through inhibition of RECK expression. | MiR-374b-5p suppresses RECK expression and promotes gastric cancer cell invasion and metastasis.
Xie J, Tan ZH, Tang X, Mo MS, Liu YP, Gan RL, Li Y, Zhang L, Li GQ., Free PMC Article | 09/12/2015 |