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    Mir30b microRNA 30b [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100314231, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    MiR-30b-5p promotes myocardial cell apoptosis in rats with myocardial infarction through regulating Wnt/beta-catenin signaling pathway.

    MiR-30b-5p promotes myocardial cell apoptosis in rats with myocardial infarction through regulating Wnt/β-catenin signaling pathway.
    Chi F, Feng L, Li Y, Zhao S, Yuan W, Jiang Y, Cheng L.

    07/27/2023
    MiR-30b-5p attenuates the inflammatory response and facilitates the functional recovery of spinal cord injury by targeting the NEFL/mTOR pathway.

    MiR-30b-5p attenuates the inflammatory response and facilitates the functional recovery of spinal cord injury by targeting the NEFL/mTOR pathway.
    Zhang H, Wang D, Tong J, Fang J, Lin Z., Free PMC Article

    12/31/2022
    ATG7-enhanced impaired autophagy exacerbates acute pancreatitis by promoting regulated necrosis via the miR-30b-5p/CAMKII pathway.

    ATG7-enhanced impaired autophagy exacerbates acute pancreatitis by promoting regulated necrosis via the miR-30b-5p/CAMKII pathway.
    Ji L, Wang ZH, Zhang YH, Zhou Y, Tang DS, Yan CS, Ma JM, Fang K, Gao L, Ren NS, Cheng L, Guo XY, Sun B, Wang G., Free PMC Article

    04/23/2022
    MiR-30b-5p Influences Chronic Exercise Arthritic Injury by Targeting Hoxa1.

    MiR-30b-5p Influences Chronic Exercise Arthritic Injury by Targeting Hoxa1.
    Li M, Gai F, Chen H.

    12/25/2021
    LncRNA KCNQ1OT1 Regulates Endoplasmic Reticulum Stress to Affect Cerebral Ischemia-Reperfusion Injury Through Targeting miR-30b/GRP78.

    LncRNA KCNQ1OT1 Regulates Endoplasmic Reticulum Stress to Affect Cerebral Ischemia-Reperfusion Injury Through Targeting miR-30b/GRP78.
    Li Y, Yi M, Wang D, Zhang Q, Yang L, Yang C.

    09/25/2021
    MiR-30b-5p and miR-22-3p restrain the fibrogenesis of post-myocardial infarction in mice via targeting PTAFR.

    MiR-30b-5p and miR-22-3p restrain the fibrogenesis of post-myocardial infarction in mice via targeting PTAFR.
    Zhao XS, Ren Y, Wu Y, Ren HK, Chen H.

    04/3/2021
    Neuro-protective roles of long non-coding RNA MALAT1 in Alzheimer's disease with the involvement of the microRNA-30b/CNR1 network and the following PI3K/AKT activation.

    Neuro-protective roles of long non-coding RNA MALAT1 in Alzheimer's disease with the involvement of the microRNA-30b/CNR1 network and the following PI3K/AKT activation.
    Li L, Xu Y, Zhao M, Gao Z.

    02/6/2021
    MicroRNA-30b regulates insulin sensitivity by targeting SERCA2b in non-alcoholic fatty liver disease.

    MicroRNA-30b regulates insulin sensitivity by targeting SERCA2b in non-alcoholic fatty liver disease.
    Dai LL, Li SD, Ma YC, Tang JR, Lv JY, Zhang YQ, Miao YL, Ma YQ, Li CM, Chu YY, Wang KH, Ma LQ, Zou CG.

    09/19/2020
    miR-30b overexpression and Sema3A siRNA could statistically significantly promote the growth of axons while inhibiting the growth of dendrites from retinal ganglion cells.

    MicroRNA-30b regulates the polarity of retinal ganglion cells by inhibiting semaphorin-3A.
    Chan-Juan H, Sen L, Li-Qianyu A, Jian Y, Rong-Di Y., Free PMC Article

    06/20/2020
    in addition, upregulated expression of miR-30b attenuated vascular calcification (VC) in vivo. Taken together, the key findings of this study identified the inhibitory role of miR-30b in VC, presenting an enhanced understanding of miRNA as a therapeutic target to curtail progressive VC in hyperphosphatemia of chronic kidney disease .

    Restoration of microRNA-30b expression alleviates vascular calcification through the mTOR signaling pathway and autophagy.
    Xu TH, Qiu XB, Sheng ZT, Han YR, Wang J, Tian BY, Yao L.

    05/30/2020
    MiR-30b contributes to oxaliplatin-induced chronic neuropathic pain through Nav1.6 down-regulation.

    MiR-30b-5p attenuates oxaliplatin-induced peripheral neuropathic pain through the voltage-gated sodium channel Na(v)1.6 in rats.
    Li L, Shao J, Wang J, Liu Y, Zhang Y, Zhang M, Zhang J, Ren X, Su S, Li Y, Cao J, Zang W.

    03/7/2020
    This study demonstrated that the expression of miR-30b and Nav1.7 was down-regulated and up-regulated, respectively, in the dorsal root ganglion of spared nerve injury rats

    MicroRNA-30b regulates expression of the sodium channel Nav1.7 in nerve injury-induced neuropathic pain in the rat.
    Shao J, Cao J, Wang J, Ren X, Su S, Li M, Li Z, Zhao Q, Zang W., Free PMC Article

    10/21/2017
    treatment with an autophagy inhibitor decreased LC3II expression.However, miR-30b overexpression decreased Pi-induced expression of autophagy-related marker genes such as BECN1, ATG5, and LC3b, whereas miR-30b downregulation increased Pi-induced expression of these genes. In addition, we found that miR-30b

    MicroRNA-30b Regulates High Phosphorus Level-Induced Autophagy in Vascular Smooth Muscle Cells by Targeting BECN1.
    Wang J, Sun YT, Xu TH, Sun W, Tian BY, Sheng ZT, Sun L, Liu LL, Ma JF, Wang LN, Yao L.

    08/5/2017
    Findings provide the first evidence that miR-30b-mediated Semaphorin3A downregulation may serve as a new strategy for the clinical treatment of optic nerve injury.

    MicroRNA-30b promotes axon outgrowth of retinal ganglion cells by inhibiting Semaphorin3A expression.
    Han F, Huo Y, Huang CJ, Chen CL, Ye J.

    02/13/2016
    Results provide evidence that Mir-30b confers protection against hypoxia/reoxygenation-induced apoptosis via modulation of Ras-PI3K-Akt pathway.

    Protective effect of microRNA-30b on hypoxia/reoxygenation-induced apoptosis in H9C2 cardiomyocytes.
    Li T, Sun ZL, Xie QY.

    05/30/2015
    The mir-30b reduced alpha-SMA excretion and upregulated E-cadherin and BMP-7 expression.

    MiR-30b is involved in methylglyoxal-induced epithelial-mesenchymal transition of peritoneal mesothelial cells in rats.
    Liu H, Zhang N, Tian D., Free PMC Article

    02/21/2015
    A critical role of NF-kappaB-mediated miR-30b modulation in Ang II-stimulated cardiomyocytes targeting Bcl-2.

    NF-κB-mediated miR-30b regulation in cardiomyocytes cell death by targeting Bcl-2.
    Wei C, Li L, Gupta S.

    09/27/2014
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