| Therapeutic potential of apelin and Elabela in cardiovascular disease. | Therapeutic potential of apelin and Elabela in cardiovascular disease.
Gao S, Chen H. | 10/4/2023 |
| Betatrophin, elabela, asprosin, glucagon and subfatin peptides in breast tissue, blood and milk in gestational diabetes. | Betatrophin, elabela, asprosin, glucagon and subfatin peptides in breast tissue, blood and milk in gestational diabetes.
Yavuz A, Aydin MA, Ugur K, Aydin S, Senol A, Baykus Y, Deniz R, Sahin İ, Yalcin MH, Gencer BT, Deniz YK, Ustebay S, Karagoz ZK, Emre E, Aydin S. | 08/25/2023 |
| Apelin/ELABELA-APJ system in cardiac hypertrophy: Regulatory mechanisms and therapeutic potential. | Apelin/ELABELA-APJ system in cardiac hypertrophy: Regulatory mechanisms and therapeutic potential.
Pang B, Jiang YR, Xu JY, Shao DX, Hao LY. | 05/8/2023 |
| Reduced Apela/APJ system expression in patients with pulmonary artery hypertension secondary to chronic obstructive pulmonary disease. | Reduced Apela/APJ system expression in patients with pulmonary artery hypertension secondary to chronic obstructive pulmonary disease.
Hu Y, Zong Y, Jin L, Zou J, Wang Z. | 04/15/2023 |
| A Case-Control Study of the APELA Gene and Hypertensive Disorders of Pregnancy. | A Case-Control Study of the APELA Gene and Hypertensive Disorders of Pregnancy.
Shimada N, Nakayama T, Umemura H, Kawana K, Yamamoto T, Uchigasaki S., Free PMC Article | 06/11/2022 |
| Elabela/toddler: New peptide with a promising future in cancer diagnostic and therapy. | Elabela/toddler: New peptide with a promising future in cancer diagnostic and therapy.
Liet B, Nys N, Siegfried G. | 12/4/2021 |
| Plasma Level of Elabela in Patients with Coronary Heart Disease and Its Correlation with the Disease Classification. | Plasma Level of Elabela in Patients with Coronary Heart Disease and Its Correlation with the Disease Classification.
Tian QP, Liu ML, Zhang YR, Ji DR, Liu SM, Zhao J, Qi YF. | 08/7/2021 |
| Circulating levels of Elabela and Apelin in the second and third trimesters of pregnancies with gestational diabetes mellitus. | Circulating levels of Elabela and Apelin in the second and third trimesters of pregnancies with gestational diabetes mellitus.
Guo YY, Li T, Liu H, Tang L, Li YC, Hu HT, Su YF, Lin Y, Wang YY, Li C, Huang HF, Jin L, Liu XM. | 06/26/2021 |
| Serum Elabela Levels Are Elevated in Patients with Hyperthyroidism. | Serum Elabela Levels Are Elevated in Patients with Hyperthyroidism.
Buyuksimsek M, Gulumsek E, Aslan MZ, Ozturk HA, Bashir AM, Icen YK, Ay N, Acibucu F, Koc M, Sumbul HE, Saler T. | 06/12/2021 |
| ELA/APELA precursor cleaved by furin displays tumor suppressor function in renal cell carcinoma through mTORC1 activation. | ELA/APELA precursor cleaved by furin displays tumor suppressor function in renal cell carcinoma through mTORC1 activation.
Soulet F, Bodineau C, Hooks KB, Descarpentrie J, Alves I, Dubreuil M, Mouchard A, Eugenie M, Hoepffner JL, López JJ, Rosado JA, Soubeyran I, Tomé M, Durán RV, Nikolski M, Villoutreix BO, Evrard S, Siegfried G, Khatib AM., Free PMC Article | 05/22/2021 |
| Association between ELABELA Serum Concentrations in First Trimester and Pregnancy-Induced Hypertension. | Association between ELABELA Serum Concentrations in First Trimester and Pregnancy-Induced Hypertension.
Ma S, Guo C, Zhang J, Long S, Tan H, You Y., Free PMC Article | 05/15/2021 |
| Elabela/Toddler and apelin bind differently to the apelin receptor. | Elabela/Toddler and apelin bind differently to the apelin receptor.
Couvineau P, Llorens-Cortes C, Iturrioz X. | 01/23/2021 |
| Elabela levels in patients with type 2 diabetes: can it be a marker for diabetic nephropathy? | Elabela levels in patients with type 2 diabetes: can it be a marker for diabetic nephropathy?
Onalan E, Doğan Y, Onalan E, Gozel N, Buran I, Donder E., Free PMC Article | 12/19/2020 |
| Peptide hormone ELABELA enhances extravillous trophoblast differentiation, but placenta is not the major source of circulating ELABELA in pregnancy. | Peptide hormone ELABELA enhances extravillous trophoblast differentiation, but placenta is not the major source of circulating ELABELA in pregnancy.
Georgiadou D, Boussata S, Ranzijn WHM, Root LEA, Hillenius S, Bij de Weg JM, Abheiden CNH, de Boer MA, de Vries JIP, Vrijkotte TGM, Lambalk CB, Kuijper EAM, Afink GB, van Dijk M., Free PMC Article | 11/21/2020 |
| Reduced ELABELA expression attenuates trophoblast invasion through the PI3K/AKT/mTOR pathway in early onset preeclampsia. | Reduced ELABELA expression attenuates trophoblast invasion through the PI3K/AKT/mTOR pathway in early onset preeclampsia.
Wang L, Zhang Y, Qu H, Xu F, Hu H, Zhang Q, Ye Y. | 08/15/2020 |
| Variants in the 5'-UTR of APELA gene may account for variability of APELA expression among individuals with preeclampsia (PE) and may play a negative regulatory role in the pathogenesis of PE. | Variants in the 5'-UTR of APELA gene in women with preeclampsia.
Yang X, Bian Y, Wan J, Li L, Yang P, Zhao S, Zhao H. | 03/28/2020 |
| decreased in maternal and cord blood in pre-eclampsia, relative to controls | Evaluation of elabela, apelin and nitric oxide findings in maternal blood of normal pregnant women, pregnant women with pre-eclampsia, severe pre-eclampsia and umbilical arteries and venules of newborns.
Deniz R, Baykus Y, Ustebay S, Ugur K, Yavuzkir Ş, Aydin S. | 02/8/2020 |
| This study identified ELA as significantly decreased in late-onset preeclampsia. An in vitro study showed that the addition of ELA significantly increased the invasion ability and proliferation of trophoblast cells. | ELABELA, as a potential diagnostic biomarker of preeclampsia, regulates abnormally shallow placentation via APJ.
Zhou L, Sun H, Cheng R, Fan X, Lai S, Deng C. | 01/4/2020 |
| No significant difference was found in plasma ELABELA levels in pregnant women who developed preeclampsia versus those who did not. | ELABELA concentration is not decreased in maternal plasma before the onset of preeclampsia.
Villie P, Lefevre G, Arrestier R, Rousseau A, Berkane N, Hertig A. | 11/23/2019 |
| Apela Promotes Cardiomyocyte Differentiation from Transgenic Human Embryonic Stem Cell Lines. | Apela Promotes Cardiomyocyte Differentiation from Transgenic Human Embryonic Stem Cell Lines.
Wang Z, Huang J. | 11/23/2019 |
| Given the role of apelin/APJ and Elabela/APJ in cardiovascular and other diseases, we believe that the combination of these agonists and antagonists with apelin and Elabela will play a corresponding role in various pathophysiological effects with further development of research. | Targeting drugs to APJ receptor: From signaling to pathophysiological effects.
Huang Z, He L, Chen Z, Chen L. | 10/5/2019 |
| The properties and biological functions of ELABELA are discussed in comparison with those of Apelin. (REVIEW) | Elabela, a newly discovered APJ ligand: Similarities and differences with Apelin.
Zhang Y, Wang Y, Lou Y, Luo M, Lu Y, Li Z, Wang Y, Miao L. | 06/29/2019 |
| ELA has an angiogenetic role in the progression of glial tumors | A Novel Candidate Molecule in the Pathological Grading of Gliomas: ELABELA.
Artas G, Ozturk S, Kuloglu T, Dagli AF, Gonen M, Artas H, Aydin S, Erol FS. | 01/26/2019 |
| The results showed that the serum ELA levels decreased gradually with the deterioration of diabetic kidney disease from the stages of normal albuminuria, microalbuminuria, macroalbuminuria, to macroalbuminuria and elevated serum creatinine. | Serum Elabela/Toddler Levels Are Associated with Albuminuria in Patients with Type 2 Diabetes.
Zhang H, Gong D, Ni L, Shi L, Xu W, Shi M, Chen J, Ai Y, Zhang X. | 09/15/2018 |
| Studies indicate that the Elabela-APJ (apelin receptor) axis may protect against pressure overload-induced heart failure. | Elabela-APJ axis: a novel therapy target for cardiovascular diseases.
Li L, Zhou Q, Li X, Chen L. | 08/18/2018 |