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    SOX21-AS1 SOX21 antisense divergent transcript 1 [ Homo sapiens (human) ]

    Gene ID: 100507533, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Long non-coding RNA SOX21-AS1: A potential tumor oncogene in human cancers.

    Long non-coding RNA SOX21-AS1: A potential tumor oncogene in human cancers.
    Lu Z, Xu J, Cao B, Jin C.

    09/12/2023
    SOX21-AS1 activated by STAT6 promotes pancreatic cancer progression via up-regulation of SOX21.

    SOX21-AS1 activated by STAT6 promotes pancreatic cancer progression via up-regulation of SOX21.
    Yu D, Zhao Z, Wang L, Qiao S, Yang Z, Wen Q, Zhu G., Free PMC Article

    11/12/2022
    Downregulation of SOX21-AS1 Alleviated Cisplatin Resistance in Cervical Cancer Through Epithelial-Mesenchymal Transition Inhibition.

    Downregulation of SOX21-AS1 Alleviated Cisplatin Resistance in Cervical Cancer Through Epithelial-Mesenchymal Transition Inhibition.
    Tian J, Li Z, Jiang Y, Gu W, Kong E, Hao Q, Kong B, Sun L.

    10/29/2022
    Long non-coding RNA SOX21-AS1 modulates lung cancer progress upon microRNA miR-24-3p/PIM2 axis.

    Long non-coding RNA SOX21-AS1 modulates lung cancer progress upon microRNA miR-24-3p/PIM2 axis.
    Wang F, Gu T, Chen Y, Chen Y, Xiong D, Zhu Y., Free PMC Article

    01/22/2022
    Long non-coding RNA SOX21-AS1 enhances the stemness of breast cancer cells via the Hippo pathway.

    Long non-coding RNA SOX21-AS1 enhances the stemness of breast cancer cells via the Hippo pathway.
    Li L, Meng D, Wang R., Free PMC Article

    12/18/2021
    Aberrant Methylation of the SOX21-AS1 Promoter Region Promotes Gene Expression and Its Clinical Value in Cervical Cancer.

    Aberrant Methylation of the SOX21-AS1 Promoter Region Promotes Gene Expression and Its Clinical Value in Cervical Cancer.
    Du P, Zhi Y, Wang R, Li Y, Li H, Zhang X, Cheng G, Li X.

    11/27/2021
    SRY-Box 21 Antisense RNA 1 Knockdown Diminishes Amyloid Beta25-35-Induced Neuronal Damage by miR-132/PI3K/AKT Pathway.

    SRY-Box 21 Antisense RNA 1 Knockdown Diminishes Amyloid Beta(25-35)-Induced Neuronal Damage by miR-132/PI3K/AKT Pathway.
    Gu F, Ji D, Ni H, Chen D.

    11/6/2021
    Long noncoding RNA SOX21-AS1 regulates the progression of triple-negative breast cancer through regulation of miR-520a-5p/ORMDL3 axis.

    Long noncoding RNA SOX21-AS1 regulates the progression of triple-negative breast cancer through regulation of miR-520a-5p/ORMDL3 axis.
    Liu X, Song J, Kang Y, Wang Y, Chen A.

    08/7/2021
    LncRNA SOX21-AS1 Promotes the Growth and Invasiveness of Osteosarcoma Cells Through miR-7-5p/IRS2 Regulatory Network.

    LncRNA SOX21-AS1 Promotes the Growth and Invasiveness of Osteosarcoma Cells Through miR-7-5p/IRS2 Regulatory Network.
    Chen H, Chen J.

    07/3/2021
    SOX21-AS1 modulates neuronal injury of MMP(+)-treated SH-SY5Y cells via targeting miR-7-5p and inhibiting IRS2.

    SOX21-AS1 modulates neuronal injury of MMP(+)-treated SH-SY5Y cells via targeting miR-7-5p and inhibiting IRS2.
    Xie Y, Zhang S, Lv Z, Long T, Luo Y, Li Z.

    05/1/2021
    Silencing of long non-coding RNA SOX21-AS1 inhibits lung adenocarcinoma invasion and migration by impairing TSPAN8 via transcription factor GATA6.

    Silencing of long non-coding RNA SOX21-AS1 inhibits lung adenocarcinoma invasion and migration by impairing TSPAN8 via transcription factor GATA6.
    Xu Y, Wu H, Wu L, Xu L, Li J, Wang Q, Pu X.

    04/24/2021
    Knockdown of long non-coding RNA SOX21-AS1 attenuates amyloid-beta-induced neuronal damage by sponging miR-107.

    Knockdown of long non-coding RNA SOX21-AS1 attenuates amyloid-β-induced neuronal damage by sponging miR-107.
    Xu W, Li K, Fan Q, Zong B, Han L., Free PMC Article

    03/27/2021
    Long non-coding RNA SOX21-AS1 promotes cell proliferation and invasion through upregulating PAK7 expression by sponging miR-144-3p in glioma cells.

    Long non-coding RNA SOX21-AS1 promotes cell proliferation and invasion through upregulating PAK7 expression by sponging miR-144-3p in glioma cells.
    Gai SY, Yuan ZH.

    08/22/2020
    Knockdown of SOX21-AS1 suppressed cervical cancer cell proliferation, migration, and invasion, as well as epithelial to mesenchymal transition progress. Furthermore, microRNA-7 (miR-7) interacted with SOX21-AS1 by directly targeting the miRNA-binding site in the SOX21-AS1 sequence.

    Long noncoding RNA SOX21-AS1 promotes cervical cancer progression by competitively sponging miR-7/VDAC1.
    Zhang X, Zhao X, Li Y, Zhou Y, Zhang Z.

    06/13/2020
    Hypomethylation of the lncRNA SOX21-AS1 is associated with cervical cancer.

    Hypomethylation of the lncRNA SOX21-AS1 has clinical prognostic value in cervical cancer.
    Wang R, Li Y, Du P, Zhang X, Li X, Cheng G.

    11/2/2019
    Knockdown of SOX21-AS1 significantly inhibited LUAD cell proliferation both in vitro and in vivo and induced cell cycle phase arrest and cell apoptosis.

    A Novel Long Non-Coding RNA, SOX21-AS1, Indicates a Poor Prognosis and Promotes Lung Adenocarcinoma Proliferation.
    Lu X, Huang C, He X, Liu X, Ji J, Zhang E, Wang W, Guo R.

    11/18/2017
    Study identified SOX21-AS1 as susceptible dysfunction correlated with promoter hypermethylation in oral squamous cell carcinoma (OSCC). Low SOX21-AS1 expression may be an adverse prognostic biomarker for OSCC.

    Aberrant DNA hypermethylation-silenced SOX21-AS1 gene expression and its clinical importance in oral cancer.
    Yang CM, Wang TH, Chen HC, Li SC, Lee MC, Liou HH, Liu PF, Tseng YK, Shiue YL, Ger LP, Tsai KW., Free PMC Article

    04/29/2017
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