| Expanded phenotype and cancer risk in patients with Beckwith-Wiedemann spectrum caused by CDKN1C variants. | Expanded phenotype and cancer risk in patients with Beckwith-Wiedemann spectrum caused by CDKN1C variants.
George AM, Viswanathan A, Best LG, Monahan C, Limmina M, Ganguly A, Kalish JM. | 10/31/2024 |
| STK40 inhibits trophoblast fusion by mediating COP1 ubiquitination to degrade P57[Kip2]. | STK40 inhibits trophoblast fusion by mediating COP1 ubiquitination to degrade P57(Kip2).
Li X, Shao LZ, Li ZH, Wang YH, Cai QY, Wang S, Chen H, Sheng J, Luo X, Chen XM, Wang YX, Ding YB, Liu TH., Free PMC Article | 09/29/2024 |
| Promoter methylation and enhanced SKP2 are associated with the downregulation of CDKN1C in cervical squamous cell carcinoma. | Promoter methylation and enhanced SKP2 are associated with the downregulation of CDKN1C in cervical squamous cell carcinoma.
Roychowdhury A, Pal D, Basu M, Samadder S, Mondal R, Roy A, Roychoudhury S, Panda CK. | 05/17/2024 |
| MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57[Kip2] targeting. | MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57(Kip2) targeting.
Pomella S, Cassandri M, D'Archivio L, Porrazzo A, Cossetti C, Phelps D, Perrone C, Pezzella M, Cardinale A, Wachtel M, Aloisi S, Milewski D, Colletti M, Sreenivas P, Walters ZS, Barillari G, Di Giannatale A, Milano GM, De Stefanis C, Alaggio R, Rodriguez-Rodriguez S, Carlesso N, Vakoc CR, Velardi E, Schafer BW, Guccione E, Gatz SA, Wasti A, Yohe M, Ignatius M, Quintarelli C, Shipley J, Miele L, Khan J, Houghton PJ, Marampon F, Gryder BE, De Angelis B, Locatelli F, Rota R., Free PMC Article | 01/31/2024 |
| Structure-Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Bipartite Nuclear Localization Signal. | Structure-Function Analysis of p57KIP2 in the Human Pancreatic Beta Cell Reveals a Bipartite Nuclear Localization Signal.
Choleva L, Wang P, Liu H, Wood O, Lambertini L, Scott DK, Karakose E, Stewart AF., Free PMC Article | 01/11/2024 |
| Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma. | Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma.
Sircar A, Singh S, Xu-Monette ZY, Coyle KM, Hilton LK, Chavdoula E, Ranganathan P, Jain N, Hanel W, Tsichlis P, Alinari L, Peterson BR, Tao J, Muthusamy N, Baiocchi R, Epperla N, Young KH, Morin R, Sehgal L., Free PMC Article | 10/11/2023 |
| PIK3R3 is upregulated in liver cancer and activates Akt signaling to control cancer growth by regulation of CDKN1C and SMC1A. | PIK3R3 is upregulated in liver cancer and activates Akt signaling to control cancer growth by regulation of CDKN1C and SMC1A.
Lin W, Wang K, Mo J, Wang L, Song Z, Jiang H, Wang C, Jin C., Free PMC Article | 07/23/2023 |
| Identification and targeting of a HES1-YAP1-CDKN1C functional interaction in fusion-negative rhabdomyosarcoma. | Identification and targeting of a HES1-YAP1-CDKN1C functional interaction in fusion-negative rhabdomyosarcoma.
Kovach AR, Oristian KM, Kirsch DG, Bentley RC, Cheng C, Chen X, Chen PH, Chi JA, Linardic CM., Free PMC Article | 10/29/2022 |
| High Maternal Serum Estradiol in First Trimester of Multiple Pregnancy Contributes to Small for Gestational Age via DNMT1-Mediated CDKN1C Upregulation. | High Maternal Serum Estradiol in First Trimester of Multiple Pregnancy Contributes to Small for Gestational Age via DNMT1-Mediated CDKN1C Upregulation.
Hu XL, Shi S, Hou NN, Meng Y, Li M, Liu AX, Lu YC, Li JY, Sheng JZ, Zhu YM, Huang HF., Free PMC Article | 04/30/2022 |
| Loss of p57 Expression in Conceptions Other Than Complete Hydatidiform Mole: A Case Series With Emphasis on the Etiology, Genetics, and Clinical Significance. | Loss of p57 Expression in Conceptions Other Than Complete Hydatidiform Mole: A Case Series With Emphasis on the Etiology, Genetics, and Clinical Significance.
Xing D, Miller K, Beierl K, Ronnett BM., Free PMC Article | 02/19/2022 |
| CDKN1C as a prognostic biomarker correlated with immune infiltrates and therapeutic responses in breast cancer patients. | CDKN1C as a prognostic biomarker correlated with immune infiltrates and therapeutic responses in breast cancer patients.
Lai J, Lin X, Cao F, Mok H, Chen B, Liao N., Free PMC Article | 02/19/2022 |
| Complementary role of p57kip2 immunostaining in diagnosing hydatidiform mole subtypes. | Complementary role of p57kip2 immunostaining in diagnosing hydatidiform mole subtypes.
Zainal N, Kampan NC, Rose IM, Ghazali R, Shafiee MN, Yussoff NH, Tamil A, Jamil MA, Hussin NH. | 02/5/2022 |
| Expression of p57(KIP2) reduces growth and invasion, and induces syncytialization in a human placental choriocarcinoma cell line, BeWo. | Expression of p57(KIP2) reduces growth and invasion, and induces syncytialization in a human placental choriocarcinoma cell line, BeWo.
Takahashi K, Yoneyama Y, Koizumi N, Utoguchi N, Kanayama N, Higashi N. | 12/25/2021 |
| Prenatal molecular testing and diagnosis of Beckwith-Wiedemann syndrome. | Prenatal molecular testing and diagnosis of Beckwith-Wiedemann syndrome.
Baker SW, Ryan E, Kalish JM, Ganguly A. | 12/18/2021 |
| Protein and genetic expression of CDKN1C and IGF2 and clinical features related to human umbilical cord length. | Protein and genetic expression of CDKN1C and IGF2 and clinical features related to human umbilical cord length.
Olaya-C M, Ayala-Ramirez P, Sanchez-Barbero AI, Guzmán-P SL, Gil F, Silva JL, Seedbed in Perinatal Medicine, Bernal JE. | 10/30/2021 |
| Novel mutation points to a hot spot in CDKN1C causing Silver-Russell syndrome. | Novel mutation points to a hot spot in CDKN1C causing Silver-Russell syndrome.
Binder G, Ziegler J, Schweizer R, Habhab W, Haack TB, Heinrich T, Eggermann T., Free PMC Article | 10/23/2021 |
| Dephosphorylation of the Proneural Transcription Factor ASCL1 Re-Engages a Latent Post-Mitotic Differentiation Program in Neuroblastoma. | Dephosphorylation of the Proneural Transcription Factor ASCL1 Re-Engages a Latent Post-Mitotic Differentiation Program in Neuroblastoma.
Ali FR, Marcos D, Chernukhin I, Woods LM, Parkinson LM, Wylie LA, Papkovskaia TD, Davies JD, Carroll JS, Philpott A., Free PMC Article | 10/2/2021 |
| A Beckwith-Wiedemann-Associated CDKN1C Mutation Allows the Identification of a Novel Nuclear Localization Signal in Human p57(Kip2). | A Beckwith-Wiedemann-Associated CDKN1C Mutation Allows the Identification of a Novel Nuclear Localization Signal in Human p57(Kip2).
Stampone E, Bencivenga D, Barone C, Di Finizio M, Della Ragione F, Borriello A., Free PMC Article | 09/25/2021 |
| Variable Expressivity of the Beckwith-Wiedemann Syndrome in Four Pedigrees Segregating Loss-of-Function Variants of CDKN1C. | Variable Expressivity of the Beckwith-Wiedemann Syndrome in Four Pedigrees Segregating Loss-of-Function Variants of CDKN1C.
Sparago A, Cerrato F, Pignata L, Cammarata-Scalisi F, Garavelli L, Piscopo C, Vancini A, Riccio A., Free PMC Article | 09/4/2021 |
| Investigation of (epi)genotype causes and follow-up manifestations in the patients with classical and atypical phenotype of Beckwith-Wiedemann spectrum. | Investigation of (epi)genotype causes and follow-up manifestations in the patients with classical and atypical phenotype of Beckwith-Wiedemann spectrum.
Tüysüz B, Güneş N, Geyik F, Yeşil G, Celkan T, Vural M. | 09/4/2021 |
| Improved molecular detection of mosaicism in Beckwith-Wiedemann Syndrome. | Improved molecular detection of mosaicism in Beckwith-Wiedemann Syndrome.
Baker SW, Duffy KA, Richards-Yutz J, Deardorff MA, Kalish JM, Ganguly A., Free PMC Article | 09/4/2021 |
| Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer. | Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer.
Prekovic S, Schuurman K, Mayayo-Peralta I, Manjón AG, Buijs M, Yavuz S, Wellenstein MD, Barrera A, Monkhorst K, Huber A, Morris B, Lieftink C, Chalkiadakis T, Alkan F, Silva J, Győrffy B, Hoekman L, van den Broek B, Teunissen H, Debets DO, Severson T, Jonkers J, Reddy T, de Visser KE, Faller W, Beijersbergen R, Altelaar M, de Wit E, Medema R, Zwart W., Free PMC Article | 08/7/2021 |
| USP7 promotes proliferation of papillary thyroid carcinoma cells through TBX3-mediated p57(KIP2) repression. | USP7 promotes proliferation of papillary thyroid carcinoma cells through TBX3-mediated p57(KIP2) repression.
Xie P, Wang H, Xie J, Huang Z, Chen S, Cheng X, Zhang X, Liu F, Li Y, Huang D. | 07/3/2021 |
| Regulation of p27(Kip1) and p57(Kip2) Functions by Natural Polyphenols. | Regulation of p27(Kip1) and p57(Kip2) Functions by Natural Polyphenols.
Russo GL, Stampone E, Cervellera C, Borriello A., Free PMC Article | 06/26/2021 |
| CDKN1C-mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib. | CDKN1C-mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib.
Kagiyama Y, Fujita S, Shima Y, Yamagata K, Katsumoto T, Nakagawa M, Honma D, Adachi N, Araki K, Kato A, Inaki K, Ono Y, Fukuhara S, Kobayashi Y, Tobinai K, Kitabayashi I., Free PMC Article | 06/19/2021 |