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    Qsox1 quiescin Q6 sulfhydryl oxidase 1 [ Mus musculus (house mouse) ]

    Gene ID: 104009, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The disulfide catalyst QSOX1 maintains the colon mucosal barrier by regulating Golgi glycosyltransferases.

    The disulfide catalyst QSOX1 maintains the colon mucosal barrier by regulating Golgi glycosyltransferases.
    Ilani T, Reznik N, Yeshaya N, Feldman T, Vilela P, Lansky Z, Javitt G, Shemesh M, Brenner O, Elkis Y, Varsano N, Jaramillo AM, Evans CM, Fass D., Free PMC Article

    02/14/2023
    Functional significance of mouse seminal vesicle sulfhydryl oxidase on sperm capacitation in vitro.

    Functional significance of mouse seminal vesicle sulfhydryl oxidase on sperm capacitation in vitro.
    Balu R, Ramachandran SS, Mathimaran A, Jeyaraman J, Paramasivam SG.

    09/3/2022
    Polarized epithelium-sperm co-culture system reveals stimulatory factors for the secretion of mouse epididymal quiescin sulfhydryl oxidase 1.

    Polarized epithelium-sperm co-culture system reveals stimulatory factors for the secretion of mouse epididymal quiescin sulfhydryl oxidase 1.
    Wei YS, Lin WZ, Wang TE, Lee WY, Li SH, Lin FJ, Nixon B, Sipilä P, Tsai PS., Free PMC Article

    06/11/2022
    Quiescin/sulfhydryl oxidase 1b (QSOX1b) induces migration and proliferation of vascular smooth muscle cells by distinct redox pathways

    Quiescin/sulfhydryl oxidase 1b (QSOX1b) induces migration and proliferation of vascular smooth muscle cells by distinct redox pathways.
    França KC, Martinez PA, Prado ML, Lo SM, Borges BE, Zanata SM, San Martin A, Nakao LS., Free PMC Article

    04/18/2020
    our study provides the first comprehensive comparisons between QSOX1 and QSOX2 in the mouse epididymis, revealing their distinct epididymal distribution, cellular localization, mechanisms of secretion and sperm membrane association

    Mouse quiescin sulfhydryl oxidases exhibit distinct epididymal luminal distribution with segment-specific sperm surface associations.
    Wang TE, Li SH, Minabe S, Anderson AL, Dun MD, Maeda KI, Matsuda F, Chang HW, Nixon B, Tsai PJ.

    09/28/2019
    the data indicated that QSOX1 is required 1) for a proper protein folding in the endo/sarcoplasmic reticulum (ER/SR) and 2) for resolution and protective response during acute stress.

    QSOX1, a novel actor of cardiac protection upon acute stress in mice.
    Caillard A, Sadoune M, Cescau A, Meddour M, Gandon M, Polidano E, Delcayre C, Da Silva K, Manivet P, Gomez AM, Cohen-Solal A, Vodovar N, Li Z, Mebazaa A, Samuel JL.

    09/21/2019
    Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms, in particular, by the serum QSOX1.

    Serum thioredoxin reductase is highly increased in mice with hepatocellular carcinoma and its activity is restrained by several mechanisms.
    Zhang L, Cheng Q, Zhang L, Wang Y, Merrill GF, Ilani T, Fass D, Arnér ESJ, Zhang J.

    01/6/2018
    QSOX1 inhibits autophagy in breast cancer cells.

    QSOX1 inhibits autophagic flux in breast cancer cells.
    Poillet L, Pernodet N, Boyer-Guittaut M, Adami P, Borg C, Jouvenot M, Delage-Mourroux R, Despouy G., Free PMC Article

    02/21/2015
    crystal structure

    The dynamic disulphide relay of quiescin sulphydryl oxidase.
    Alon A, Grossman I, Gat Y, Kodali VK, DiMaio F, Mehlman T, Haran G, Baker D, Thorpe C, Fass D., Free PMC Article

    09/29/2012
    cloned skin SOx cDNA and characterized it as one of the disulfide (S-S) cross-linking enzymes

    Sulfhydryl oxidase (SOx) from mouse epidermis: molecular cloning, nucleotide sequence, and expression of recombinant protein in the cultured cells.
    Matsuba S, Suga Y, Ishidoh K, Hashimoto Y, Takamori K, Kominami E, Wilhelm B, Seitz J, Ogawa H.

    01/21/2010
    In seminiferous tubules, where a high level of expression was noticed, QSOX might play an important physiological role in sperm function and serve as a marker for the diagnosis of male infertility.

    Cell-specific localization of the sulphydryl oxidase QSOX in rat peripheral tissues.
    Tury A, Mairet-Coello G, Esnard-Fève A, Benayoun B, Risold PY, Griffond B, Fellmann D.

    01/21/2010
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