| PGRMC2 and HLA-G regulate immune homeostasis in a microphysiological model of human maternal-fetal membrane interface. | PGRMC2 and HLA-G regulate immune homeostasis in a microphysiological model of human maternal-fetal membrane interface.
Lintao RCV, Richardson LS, Kammala AK, Chapa J, Yunque-Yap DA, Khanipov K, Golovko G, Dalmacio LMM, Menon R., Free PMC Article | 08/26/2024 |
| Deciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach. | Deciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach.
Medina-Laver Y, Gonzalez-Martin R, de Castro P, Diaz-Hernandez I, Alama P, Quiñonero A, Palomar A, Dominguez F. | 05/9/2024 |
| Progesterone receptor membrane component 2 is critical for human placental extravillous trophoblast invasion. | Progesterone receptor membrane component 2 is critical for human placental extravillous trophoblast invasion.
Yokouchi-Konishi T, Liu Y, Feng L. | 02/15/2024 |
| The role of progesterone receptor membrane component (PGRMC) in the endometrium. | The role of progesterone receptor membrane component (PGRMC) in the endometrium.
Velázquez Hernández DM, Vázquez-Martínez ER, Camacho-Arroyo I. | 07/2/2022 |
| show that progesterone receptor membrane component 2 (PGRMC2) is required for delivery of labile, or signalling haem, to the nucleus | PGRMC2 is an intracellular haem chaperone critical for adipocyte function.
Galmozzi A, Kok BP, Kim AS, Montenegro-Burke JR, Lee JY, Spreafico R, Mosure S, Albert V, Cintron-Colon R, Godio C, Webb WR, Conti B, Solt LA, Kojetin D, Parker CG, Peluso JJ, Pru JK, Siuzdak G, Cravatt BF, Saez E., Free PMC Article | 03/28/2020 |
| Results found PGRMC2 to be targeted by miR-3687. Further data indicate that PGRMC2 mRNA expression in oesophageal squamous cell carcinoma (ESCC) may be related to cell proliferation and local progression. | Differential miRNA Expression in Basaloid Squamous Cell Carcinoma of the Oesophagus: miR-3687 Targets PGRMC2.
Nakamura J, Furuya S, Hagio K, Maruyama S, Shiraishi K, Shimizu H, Akaike H, Hosomura N, Kawaguchi Y, Amemiya H, Kawaida H, Sudo M, Kono H, Ichikawa D. | 12/14/2019 |
| Demonstrate a change in myometriumPGRMC1 expression and changes in PGRMC1 and PGRMC2 cell localisation in association with parturition. | Changes in myometrial expression of progesterone receptor membrane components 1 and 2 are associated with human parturition at term.
Wang R, Sheehan PM, Brennecke SP. | 04/15/2017 |
| It deserves further examination as data point to a role of PGRMC2 as tumor suppressor, migration inhibitor and regulator of cytochrome P450 proteins. | PGRMC2, a yet uncharacterized protein with potential as tumor suppressor, migration inhibitor, and regulator of cytochrome P450 enzyme activity.
Wendler A, Wehling M. | 11/8/2014 |
| In secretory phase endometrium from women with advanced stage endometriosis, PGRMC-2 expression is downregulated. | Expression patterns of progesterone receptor membrane components 1 and 2 in endometria from women with and without endometriosis.
Bunch K, Tinnemore D, Huff S, Hoffer ZS, Burney RO, Stallings JD. | 07/19/2014 |
| Reversely, in the HO-8910 cells treated with CDDP alone, levels of both PGRMC1 and PGR were increased while the level of PGRMC2 was decreased | Progesterone protects ovarian cancer cells from cisplatin-induced inhibitory effects through progesterone receptor membrane component 1/2 as well as AKT signaling.
Zhu X, Han Y, Fang Z, Wu W, Ji M, Teng F, Zhu W, Yang X, Jia X, Zhang C. | 04/12/2014 |
| PGRMC2 inhibits migration of SKOV-3 ovarian cancer cells in vitro. | In vitro inhibition of SKOV-3 cell migration as a distinctive feature of progesterone receptor membrane component type 2 versus type 1.
Albrecht C, Huck V, Wehling M, Wendler A. | 07/27/2013 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesMaternal and fetal genetic associations of PTGER3 and PON1 with preterm birth.
Ryckman KK, Morken NH, White MJ, Velez DR, Menon R, Fortunato SJ, Magnus P, Williams SM, Jacobsson B. Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants.
Menon R, Pearce B, Velez DR, Merialdi M, Williams SM, Fortunato SJ, Thorsen P. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants.
Velez DR, Fortunato S, Thorsen P, Lombardi SJ, Williams SM, Menon R. | 12/3/2008 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | See all PubMed (2) articlesMicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.
Zhang X, Yang H, Lee JJ, Kim E, Lippman SM, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X. Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants.
Velez DR, Fortunato SJ, Thorsen P, Lombardi SJ, Williams SM, Menon R. | 10/8/2008 |
| The expression of a novel progesterone-binding protein (hmPR1/PGMRC1) was investigated. Transcripts of this protein have been detected in human sperm. | Classic and non-classic progesterone receptors are both expressed in human spermatozoa.
Lösel R, Breiter S, Seyfert M, Wehling M, Falkenstein E. | 01/21/2010 |