| Systematic transcriptome profiling of hPSC-derived osteoblasts unveils CORIN's mastery in governing osteogenesis through CEBPD modulation. | Systematic transcriptome profiling of hPSC-derived osteoblasts unveils CORIN's mastery in governing osteogenesis through CEBPD modulation.
Zhu D, Huang MF, Xu A, Gao X, Huang YW, Phan TTT, Lu L, Chi TY, Dai Y, Pang LK, Gingold JA, Tu J, Huo Z, Bazer DA, Shoemaker R, Wang J, Ambrose CG, Shen J, Kameoka J, Zhao Z, Wang LL, Zhang Y, Zhao R, Lee DF., Free PMC Article | 10/11/2024 |
| CCAAT enhancer binding protein delta activates vesicle associated membrane protein 3 transcription to enhance chemoresistance and extracellular PD-L1 expression in triple-negative breast cancer. | CCAAT enhancer binding protein delta activates vesicle associated membrane protein 3 transcription to enhance chemoresistance and extracellular PD-L1 expression in triple-negative breast cancer.
Zhao Y, Yu Y, Li X, Guo A., Free PMC Article | 04/22/2024 |
| Inhibition of MMP8 effectively alleviates manic-like behavior and reduces neuroinflammation by modulating astrocytic CEBPD. | Inhibition of MMP8 effectively alleviates manic-like behavior and reduces neuroinflammation by modulating astrocytic CEBPD.
Wang TY, Weng EF, Hsu YC, Shiu LP, Huang TW, Wu HC, Hong JS, Wang SM., Free PMC Article | 03/4/2024 |
| C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC. | C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC.
Hartl L, Roelofs JJTH, Dijk F, Bijlsma MF, Duitman J, Spek CA., Free PMC Article | 01/28/2023 |
| C/EBPdelta Suppresses Motility-Associated Gene Signatures and Reduces PDAC Cell Migration. | C/EBPδ Suppresses Motility-Associated Gene Signatures and Reduces PDAC Cell Migration.
Hartl L, Maarschalkerweerd PAF, Butler JM, Manz XD, Thijssen VLJL, Bijlsma MF, Duitman J, Spek CA., Free PMC Article | 11/19/2022 |
| CCAAT/enhancer binding protein (C/EBP) delta promotes the expression of PTX3 and macrophage phagocytosis during A. fumigatus infection. | CCAAT/enhancer binding protein (C/EBP) delta promotes the expression of PTX3 and macrophage phagocytosis during A. fumigatus infection.
Liu L, Zhong J, Chen B, Wang W, Xi H, Su X. | 05/28/2022 |
| Angiogenesis Driven by the CEBPD-hsa-miR-429-VEGFA Signaling Axis Promotes Urothelial Carcinoma Progression. | Angiogenesis Driven by the CEBPD-hsa-miR-429-VEGFA Signaling Axis Promotes Urothelial Carcinoma Progression.
Chan TC, Hsing CH, Shiue YL, Huang SK, Hsieh KL, Kuo YH, Li CF., Free PMC Article | 04/16/2022 |
| C/EBPdelta drives key endocrine signals in the human amnion at parturition. | C/EBPδ drives key endocrine signals in the human amnion at parturition.
Lu JW, Wang WS, Zhou Q, Ling LJ, Ying H, Sun Y, Myatt L, Sun K., Free PMC Article | 02/12/2022 |
| PERK signaling through C/EBPdelta contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells. | PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells.
Sheshadri N, Poria DK, Sharan S, Hu Y, Yan C, Koparde VN, Balamurugan K, Sterneck E., Free PMC Article | 02/5/2022 |
| Non-Tumor CCAAT/Enhancer-Binding Protein Delta Potentiates Tumor Cell Extravasation and Pancreatic Cancer Metastasis Formation. | Non-Tumor CCAAT/Enhancer-Binding Protein Delta Potentiates Tumor Cell Extravasation and Pancreatic Cancer Metastasis Formation.
Duitman J, Hartl L, Roelofs JJTH, Bijlsma MF, Spek CA., Free PMC Article | 10/30/2021 |
| [CCAAT/enhancer binding protein delta inhibits invasion and metastasis of liver cancer by regulating M1 type macrophages polarization]. | [CCAAT/enhancer binding protein δ inhibits invasion and metastasis of liver cancer by regulating M1 type macrophages polarization].
Li M, Xiong YF, Huang XJ, Chen TA, Li JD. | 09/18/2021 |
| MiR-324-5p/PTPRD/CEBPD axis promotes papillary thyroid carcinoma progression via microenvironment alteration. | MiR-324-5p/PTPRD/CEBPD axis promotes papillary thyroid carcinoma progression via microenvironment alteration.
Yang Y, Xia S, Zhang L, Wang W, Chen L, Zhan W., Free PMC Article | 07/10/2021 |
| CCAAT/enhancer binding protein delta is a transcriptional repressor of alpha-synuclein. | CCAAT/enhancer binding protein δ is a transcriptional repressor of α-synuclein.
Valente T, Dentesano G, Ezquerra M, Fernandez-Santiago R, Martinez-Martin J, Gallastegui E, Domuro C, Compta Y, Martí MJ, Bachs O, Márquez-Kisinousky L, Straccia M, Solà C, Saura J., Free PMC Article | 07/3/2021 |
| Shikonin inhibits CEBPD downregulation in IL17treated HaCaT cells and in an imiquimodinduced psoriasis model. | Shikonin inhibits CEBPD downregulation in IL‑17‑treated HaCaT cells and in an imiquimod‑induced psoriasis model.
Lan XO, Wang HX, Qi RQ, Xu YY, Yu YJ, Yang Y, Guo H, Gao XH, Geng L., Free PMC Article | 04/24/2021 |
| C/EBPdelta-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake. | C/EBPδ-Slug-Lox1 axis promotes metastasis of lung adenocarcinoma via oxLDL uptake.
Wang D, Cheng X, Li Y, Guo M, Zhao W, Qiu J, Zheng Y, Meng M, Ping X, Chen X, Wang S, Luo J, Luo Q, Ma X, Xu L. | 01/9/2021 |
| Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer. | Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer.
Zhou Y, Liu F, Xu Q, Yang B, Li X, Jiang S, Hu L, Zhang X, Zhu L, Li Q, Zhu X, Shao H, Dai M, Shen Y, Ni B, Wang S, Zhang Z, Teng Y., Free PMC Article | 12/5/2020 |
| Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD. | Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD.
Sun X, Jefferson P, Zhou Q, Angelastro JM, Greene LA., Free PMC Article | 12/5/2020 |
| This is the first report showing the activation of PDGFA expression by CEBPD through IL-1beta treatment and a novel CEBPD function in maintaining the self-renewal feature of glioma stem-like cells | CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation.
Wang SM, Lin HY, Chen YL, Hsu TI, Chuang JY, Kao TJ, Ko CY., Free PMC Article | 01/18/2020 |
| Our findings suggest that C/EBPdelta regulates the phenotype of normal fallopian tube cells by acting on downstream regulatory factors that are implicated in the development of ovarian serous carcinogenesis | CCAAT/enhancer binding protein delta (C/EBPδ) demonstrates a dichotomous role in tumour initiation and promotion of epithelial carcinoma.
Sowamber R, Chehade R, Bitar M, Dodds LV, Milea A, Slomovitz B, Shaw PA, George SHL., Free PMC Article | 12/21/2019 |
| CEBPD role in the breast cancer stem cells.CEBPD is a link that engages two positive feedback loops, in part by directly targeting the IL-6 receptor gene, and, thus, amplifying IL-6 and HIF-1 signaling in breast cancer. | C/EBPδ links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes.
Balamurugan K, Mendoza-Villanueva D, Sharan S, Summers GH, Dobrolecki LE, Lewis MT, Sterneck E., Free PMC Article | 12/7/2019 |
| CEBPD acts as a tumor suppressor inhepatocellular carcinoma (HCC), its action does not involve impairing compartment expansion per se but more likely acts through improving anticancer immunity. | Action and clinical significance of CCAAT/enhancer-binding protein delta in hepatocellular carcinoma.
Liu P, Cao W, Ma B, Li M, Chen K, Sideras K, Duitman JW, Sprengers D, Khe Tran TC, Ijzermans JNM, Biermann K, Verheij J, Spek CA, Kwekkeboom J, Pan Q, Peppelenbosch MP. | 11/9/2019 |
| MAIT cells selectively expressed CCAAT/enhancer-binding protein delta (C/EBPdelta). Knockdown of C/EBPdelta diminished expression of FUT7, ST3GAL4 and CCR6, decreasing MAIT cell rolling and arrest, and consequently the cells' ability to cross an endothelial monolayer in vitro and extravasate in mice. | C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation.
Lee CH, Zhang HH, Singh SP, Koo L, Kabat J, Tsang H, Singh TP, Farber JM., Free PMC Article | 07/20/2019 |
| gemcabene decreases CRP by C/EBP-delta and NF-kappaB-mediated transcriptional mechanism and suppresses IL-6 and IL-1beta-induced CRP production. | Gemcabene, a first-in-class lipid-lowering agent in late-stage development, down-regulates acute-phase C-reactive protein via C/EBP-δ-mediated transcriptional mechanism.
Srivastava RAK, Cornicelli JA, Markham B, Bisgaier CL., Free PMC Article | 12/22/2018 |
| tudy underscores how CEBPD functions at the junction of inflammation and lipid accumulation in M1 macrophages | CCAAT/enhancer-binding protein delta promotes intracellular lipid accumulation in M1 macrophages of vascular lesions.
Lai HY, Hsu LW, Tsai HH, Lo YC, Yang SH, Liu PY, Wang JM. | 06/9/2018 |
| the EGFR/STAT3 pathway contributed to CDDP-induced CEBPD expression in UCUB cells. Gefitinib and S3I-201 treatment significantly reduced the expression of CEBPD and enhanced the sensitivity of CDDP-resistant UCUB cells to CDDP and paclitaxel | Inhibition of the EGFR/STAT3/CEBPD Axis Reverses Cisplatin Cross-resistance with Paclitaxel in the Urothelial Carcinoma of the Urinary Bladder.
Wang WJ, Li CF, Chu YY, Wang YH, Hour TC, Yen CJ, Chang WC, Wang JM. | 02/10/2018 |