| BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML. | BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML.
Kumar B, Singh A, Basar R, Uprety N, Li Y, Fan H, Cortes AKN, Kaplan M, Acharya S, Shaim H, Xu AC, Wu M, Ensley E, Fang D, Banerjee PP, Garcia LM, Tiberti S, Lin P, Rafei H, Munir MN, Moore M, Shanley M, Mendt M, Kerbauy LN, Liu B, Biederstädt A, Gokdemir E, Ghosh S, Kundu K, Reyes-Silva F, Jiang XR, Wan X, Gilbert AL, Dede M, Mohanty V, Dou J, Zhang P, Liu E, Muniz-Feliciano L, Deyter GM, Jain AK, Rodriguez-Sevilla JJ, Colla S, Garcia-Manero G, Shpall EJ, Chen K, Abbas HA, Rai K, Rezvani K, Daher M. | 09/19/2024 |
| BATF promotes extramedullary infiltration through TGF-beta1/Smad/MMPs axis in acute myeloid leukemia. | BATF promotes extramedullary infiltration through TGF-β1/Smad/MMPs axis in acute myeloid leukemia.
Zhang R, Miao J, Zhai M, Liu R, Li F, Xu X, Huang L, Wang T, Yang R, Yang R, Wang Y, He A, Wang J. | 08/1/2024 |
| Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells. | Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells.
Shan F, Cillo AR, Cardello C, Yuan DY, Kunning SR, Cui J, Lampenfeld C, Williams AM, McDonough AP, Pennathur A, Luketich JD, Kirkwood JM, Ferris RL, Bruno TC, Workman CJ, Benos PV, Vignali DAA., Free PMC Article | 09/22/2023 |
| Relative Expression of BATF and CD112 in PBMC of Patients with Chronic Lymphocytic Leukemia. | Relative Expression of BATF and CD112 in PBMC of Patients with Chronic Lymphocytic Leukemia.
Najafi A, Sabaghi M, Asgarian-Omran H, Valadan R, Shekarriz R, Zaboli E, Janbabai G, Tehrani M., Free PMC Article | 07/5/2023 |
| BATF reprograms the tumor immune status. | BATF reprograms the tumor immune status.
Fan T, Xiao C, Muhammad S, Li C, He J. | 01/21/2023 |
| Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells. | Depletion of BATF in CAR-T cells enhances antitumor activity by inducing resistance against exhaustion and formation of central memory cells.
Zhang X, Zhang C, Qiao M, Cheng C, Tang N, Lu S, Sun W, Xu B, Cao Y, Wei X, Wang Y, Han W, Wang H. | 12/3/2022 |
| BATF epigenetically and transcriptionally controls the activation program of regulatory T cells in human tumors. | BATF epigenetically and transcriptionally controls the activation program of regulatory T cells in human tumors.
Itahashi K, Irie T, Yuda J, Kumagai S, Tanegashima T, Lin YT, Watanabe S, Goto Y, Suzuki J, Aokage K, Tsuboi M, Minami Y, Ishii G, Ohe Y, Ise W, Kurosaki T, Suzuki Y, Koyama S, Nishikawa H. | 10/15/2022 |
| A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation. | A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation.
Shetty A, Tripathi SK, Junttila S, Buchacher T, Biradar R, Bhosale SD, Envall T, Laiho A, Moulder R, Rasool O, Galande S, Elo LL, Lahesmaa R., Free PMC Article | 06/11/2022 |
| Supervised machine learning algorithm identified KRT20, BATF and TP63 as biologically relevant biomarkers for bladder biopsy specimens from interstitial cystitis/bladder pain syndrome patients. | Supervised machine learning algorithm identified KRT20, BATF and TP63 as biologically relevant biomarkers for bladder biopsy specimens from interstitial cystitis/bladder pain syndrome patients.
Kamasako T, Kaga K, Inoue KI, Hariyama M, Yamanishi T. | 05/7/2022 |
| Prognostic Value of DNA Methylation-Driven Genes in Clear Cell Renal Cell Carcinoma: A Study Based on Methylation and Transcriptome Analyses. | Prognostic Value of DNA Methylation-Driven Genes in Clear Cell Renal Cell Carcinoma: A Study Based on Methylation and Transcriptome Analyses.
Hu M, Xie J, Hou H, Liu M, Wang J., Free PMC Article | 05/29/2021 |
| results reveal that JunB, c-Jun, and Bach2 cooperate with BATF to contribute to the specificity of BATF-dependent cytokine induction in Th subsets. | BATF-Interacting Proteins Dictate Specificity in Th Subset Activity.
Fu Y, Koh B, Kuwahara M, Ulrich BJ, Kharwadkar R, Yamashita M, Kaplan MH., Free PMC Article | 05/23/2020 |
| BATF-dependent pathogenic GM-CSF+ effector T cells are critical promoters of intestinal inflammation in graft-versus-host disease | BATF-dependent IL-7RhiGM-CSF+ T cells control intestinal graft-versus-host disease.
Ullrich E, Abendroth B, Rothamer J, Huber C, Büttner-Herold M, Buchele V, Vogler T, Longerich T, Zundler S, Völkl S, Beilhack A, Rose-John S, Wirtz S, Weber GF, Ghimire S, Kreutz M, Holler E, Mackensen A, Neurath MF, Hildner K., Free PMC Article | 07/20/2019 |
| Findings demonstrate that peripheral and intrahepatic BATF expressions are dramatically increased in chronic hepatitis B (CHB) patients, which might boost the differentiation of Th17 cells and the release of associated cytokine during chronic HBV infection. | Increased BATF expression is associated with the severity of liver damage in patients with chronic hepatitis B.
Wang LY, Fan YC, Zhao J, Ji XF, Wang K. | 09/15/2018 |
| BATF plays a key role in the differentiation of T helper cell subsets and Ig class-switching. Apart from that we suggest an important function in mast cell development and in murine models of allergic asthma, it was observed that mice deficient for Batf are protected from the disease. Hence, the previous findings on BATF make it an interesting target for the treatment of Th cell-derived-cytokine-driven diseases. | The transcription factor BATF modulates cytokine-mediated responses in T cells.
Sopel N, Graser A, Mousset S, Finotto S. | 01/20/2018 |
| Retinoic acid signaling and BATF productions are activated in IgAN patients compared with controls. | Regulation of IgA Class Switch Recombination in Immunoglobulin A Nephropathy: Retinoic Acid Signaling and BATF.
He L, Peng X, Chen Y, Liu G, Liu Z, Zhu J, Liu Y, Liu H, Liang Y, Liu F, Sun L, Peng Y. | 01/6/2018 |
| BATF/JUN-B and BATF/C-JUN complexes play important roles in OA cartilage destruction through regulating anabolic and catabolic gene expression in chondrocytes. | Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.
Rhee J, Park SH, Kim SK, Kim JH, Ha CW, Chun CH, Chun JS., Free PMC Article | 06/3/2017 |
| Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorgammaT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung | Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorγT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung.
Balabko L, Andreev K, Burmann N, Schubert M, Mathews M, Trufa DI, Reppert S, Rau T, Schicht M, Sirbu H, Hartmann A, Finotto S., Free PMC Article | 10/10/2015 |
| data strongly support a model in which EBNA3A is tethered to DNA through a BATF-containing protein complexes to enable continuous cell proliferation | Epstein-Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes.
Schmidt SC, Jiang S, Zhou H, Willox B, Holthaus AM, Kharchenko PV, Johannsen EC, Kieff E, Zhao B., Free PMC Article | 05/2/2015 |
| increase expression in children with recurrent asthma | The activating protein 1 transcription factor basic leucine zipper transcription factor, ATF-like (BATF), regulates lymphocyte- and mast cell-driven immune responses in the setting of allergic asthma.
Übel C, Sopel N, Graser A, Hildner K, Reinhardt C, Zimmermann T, Rieker RJ, Maier A, Neurath MF, Murphy KM, Finotto S. | 03/15/2014 |
| The activator protein 1 (AP1) family transcription factor BATF (B cell, activating transcription factor-like) was among the genes enriched in Th9 cells and was required for the expression of IL-9 and other Th9-associated genes. | Th9 cell development requires a BATF-regulated transcriptional network.
Jabeen R, Goswami R, Awe O, Kulkarni A, Nguyen ET, Attenasio A, Walsh D, Olson MR, Kim MH, Tepper RS, Sun J, Kim CH, Taparowsky EJ, Zhou B, Kaplan MH., Free PMC Article | 02/22/2014 |
| PD-1 inhibits T cell function by upregulating BATF. | Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF.
Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, Julg B, Jesneck JL, Brosnahan K, Imam S, Russell K, Toth I, Piechocka-Trocha A, Dolfi D, Angelosanto J, Crawford A, Shin H, Kwon DS, Zupkosky J, Francisco L, Freeman GJ, Wherry EJ, Kaufmann DE, Walker BD, Ebert B, Haining WN., Free PMC Article | 11/6/2010 |
| up-regulated dramatically within 24 h following the infection of established and primary human B cells with EBV by the action of EBNA2 and activated Notch protein | EBNA2 and activated Notch induce expression of BATF.
Johansen LM, Deppmann CD, Erickson KD, Coffin WF 3rd, Thornton TM, Humphrey SE, Martin JM, Taparowsky EJ., Free PMC Article | 01/21/2010 |
| Overexpression of human BATF in transgenic mice disrupts the development of thymus-derived NKT cells | BATF transgenic mice reveal a role for activator protein-1 in NKT cell development.
Williams KL, Zullo AJ, Kaplan MH, Brutkiewicz RR, Deppmann CD, Vinson C, Taparowsky EJ. | 01/21/2010 |
| Phosphorylation of serine-43 converts BATF from a DNA binding into a non-DNA binding inhibitor of activator protein-1 activity. | Phosphorylation of BATF regulates DNA binding: a novel mechanism for AP-1 (activator protein-1) regulation.
Deppmann CD, Thornton TM, Utama FE, Taparowsky EJ., Free PMC Article | 01/21/2010 |