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    STIP1 stress induced phosphoprotein 1 [ Homo sapiens (human) ]

    Gene ID: 10963, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study.

    Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study.
    Stetskaya TA, Krapiva AB, Kobzeva KA, Gurtovoy DE, Komkova GV, Polonikov AV, Bushueva OY.

    03/31/2024
    LINC01226 promotes gastric cancer progression through enhancing cytoplasm-to-nucleus translocation of STIP1 and stabilizing beta-catenin protein.

    LINC01226 promotes gastric cancer progression through enhancing cytoplasm-to-nucleus translocation of STIP1 and stabilizing β-catenin protein.
    Hua H, Su T, Han L, Zhang L, Huang Y, Zhang N, Yang M.

    12/5/2023
    Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.

    Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1.
    Guo Z, Guo L.

    08/19/2023
    JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells.

    JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells.
    Chao A, Liao MJ, Chen SH, Lee YS, Tsai CN, Lin CY, Tsai CL., Free PMC Article

    03/26/2022
    The Hsp70-Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration.

    The Hsp70-Hsp90 go-between Hop/Stip1/Sti1 is a proteostatic switch and may be a drug target in cancer and neurodegeneration.
    Bhattacharya K, Picard D., Free PMC Article

    12/11/2021
    Stress-induced phosphoprotein 1 facilitates breast cancer cell progression and indicates poor prognosis for breast cancer patients.

    Stress-induced phosphoprotein 1 facilitates breast cancer cell progression and indicates poor prognosis for breast cancer patients.
    Lin L, Wen J, Lin B, Xia E, Zheng C, Ye L, Wang Y, Wang O, Chen Y.

    10/9/2021
    GLCCI1 and STIP1 variants are associated with asthma susceptibility and inhaled corticosteroid response in a Tunisian population.

    GLCCI1 and STIP1 variants are associated with asthma susceptibility and inhaled corticosteroid response in a Tunisian population.
    Salhi M, Lahmar O, Salah MO, Banić I, Binghao B, Malik W, Hamzaoui K, Turkalj M, Hamzaoui A.

    09/18/2021
    Genes involved in glucocorticoid receptor signalling affect susceptibility to mood disorders.

    Genes involved in glucocorticoid receptor signalling affect susceptibility to mood disorders.
    Szczepankiewicz D, Narożna B, Celichowski P, Sakrajda K, Kołodziejski P, Banach E, Zakowicz P, Pruszyńska-Oszmałek E, Pawlak J, Wiłkość M, Dmitrzak-Węglarz M, Skibińska M, Bejger A, Twarowska-Hauser J, Rybakowski JK, Nogowski L, Szczepankiewicz A.

    08/21/2021
    Expanding the clinical spectrum of STIP1 homology and U-box containing protein 1-associated ataxia.

    Expanding the clinical spectrum of STIP1 homology and U-box containing protein 1-associated ataxia.
    Ravel JM, Benkirane M, Calmels N, Marelli C, Ory-Magne F, Ewenczyk C, Halleb Y, Tison F, Lecocq C, Pische G, Casenave P, Chaussenot A, Frismand S, Tyvaert L, Larrieu L, Pointaux M, Drouot N, Bossenmeyer-Pourié C, Oussalah A, Guéant JL, Leheup B, Bonnet C, Anheim M, Tranchant C, Lambert L, Chelly J, Koenig M, Renaud M.

    07/31/2021
    Effects of STIP1 and GLCCI1 polymorphisms on the risk of childhood asthma and inhaled corticosteroid response in Chinese asthmatic children.

    Effects of STIP1 and GLCCI1 polymorphisms on the risk of childhood asthma and inhaled corticosteroid response in Chinese asthmatic children.
    Huang J, Hu X, Zheng X, Kuang J, Liu C, Wang X, Tang Y., Free PMC Article

    07/31/2021
    Knockdown of STIP1 inhibits the invasion of CD133positive cancer stemlike cells of the osteosarcoma MG63 cell line via the PI3K/Akt and ERK1/2 pathways.

    Knockdown of STIP1 inhibits the invasion of CD133‑positive cancer stem‑like cells of the osteosarcoma MG63 cell line via the PI3K/Akt and ERK1/2 pathways.
    Wang JH, Gong C, Guo FJ, Zhou X, Zhang MS, Qiu H, Chao TF, Liu Y, Qin L, Xiong HH.

    07/10/2021
    STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.

    STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
    Xia Y, Chen J, Liu G, Huang W, Wei X, Wei Z, He Y.

    05/8/2021
    STIP1 Tissue Expression Is Associated with Survival in Chemotherapy-Treated Bladder Cancer Patients.

    STIP1 Tissue Expression Is Associated with Survival in Chemotherapy-Treated Bladder Cancer Patients.
    Krafft U, Tschirdewahn S, Hess J, Harke NN, Hadaschik BA, Nyirády P, Szendröi A, Szücs M, Módos O, Olah C, Székely E, Reis H, Szarvas T.

    03/27/2021
    Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.

    Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.
    Darby JF, Vidler LR, Simpson PJ, Al-Lazikani B, Matthews SJ, Sharp SY, Pearl LH, Hoelder S, Workman P., Free PMC Article

    01/16/2021
    Hop depletion reduces HSF1 levels and activity and coincides with reduced stress resilience.

    Hop depletion reduces HSF1 levels and activity and coincides with reduced stress resilience.
    Chakraborty A, Edkins AL.

    01/9/2021
    The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

    The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.
    Bhattacharya K, Weidenauer L, Luengo TM, Pieters EC, Echeverría PC, Bernasconi L, Wider D, Sadian Y, Koopman MB, Villemin M, Bauer C, Rüdiger SGD, Quadroni M, Picard D., Free PMC Article

    12/12/2020
    Exome Sequencing in Individuals with Isolated Biliary Atresia.

    Exome Sequencing in Individuals with Isolated Biliary Atresia.
    Rajagopalan R, Tsai EA, Grochowski CM, Kelly SM, Loomes KM, Spinner NB, Devoto M., Free PMC Article

    11/21/2020
    Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrP(C) signaling.

    Role of FOXC1 in regulating APSCs self-renewal via STI-1/PrP(C) signaling.
    Lee YH, Lee HT, Chen CL, Chang CH, Hsu CY, Shyu WC., Free PMC Article

    10/24/2020
    STIP1 down-regulation inhibits glycolysis by suppressing PKM2 and LDHA and inactivating the Wnt/beta-catenin pathway in cervical carcinoma cells.

    STIP1 down-regulation inhibits glycolysis by suppressing PKM2 and LDHA and inactivating the Wnt/β-catenin pathway in cervical carcinoma cells.
    Li R, Li P, Wang J, Liu J.

    10/3/2020
    STIP1 is highly expressed in glioblastoma compared to normal brain tissues. Downregulation of STIP1 in glioma cells reduces cell proliferation rate and invasion and increases cell apoptosis

    Down-regulation of STIP1 regulate apoptosis and invasion of glioma cells via TRAP1/AKT signaling pathway.
    Yin H, Deng Z, Li X, Li Y, Yin W, Zhao G, Jiang D, Sun C, Zhou Y.

    04/4/2020
    These results indicate that STIP1 overexpression is associated with poor prognosis and is an independent prognostic factor in patients with pancreatic cancer

    Stress-induced phosphoprotein 1 promotes pancreatic cancer progression through activation of the FAK/AKT/MMP signaling axis.
    Jing Y, Liang W, Liu J, Zhang L, Wei J, Zhu Y, Yang J, Ji K, Zhang Y, Huang Z.

    03/28/2020
    Hop stabilises emerin and that loss of Hop alters nuclear structure via emerin degradation.

    Hop/STIP1 depletion alters nuclear structure via depletion of nuclear structural protein emerin.
    Kituyi SN, Edkins AL.

    05/18/2019
    STIP1 acts as an oncogene in colorectal carcinoma and can therefore serve as a biomarker for the prognosis of patients with CRC.

    Aberrant expression of stress-induced phosphoprotein 1 in colorectal cancer and its clinicopathologic significance.
    Zhang Z, Ren H, Yang L, Zhang X, Liang W, Wu H, Huang L, Kang J, Xu J, Zhai E, Cai S, He Y.

    05/11/2019
    Our findings indicate that elevated expression of STIP1 exhibited a metastasis-promoting effect in GC cells through activation of Wnt/beta-catenin signaling pathway.

    Stress-inducible Protein-1 promotes metastasis of gastric cancer via Wnt/β-catenin signaling pathway.
    Huang L, Zhai E, Cai S, Lin Y, Liao J, Jin H, Peng S, Xu L, Chen M, Zeng Z., Free PMC Article

    05/11/2019
    STIP1 is positively associated with sublethal heat-induced cancer cell metastasis through mediating the mesenchymal gene transcription.

    Stress-induced phosphoprotein 1 mediates hepatocellular carcinoma metastasis after insufficient radiofrequency ablation.
    Su T, Liao J, Dai Z, Xu L, Chen S, Wang Y, Peng Z, Zhang Q, Peng S, Kuang M.

    03/9/2019
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