| SUMOylation of microtubule-cleaving enzyme KATNA1 promotes microtubule severing and neurite outgrowth. | SUMOylation of microtubule-cleaving enzyme KATNA1 promotes microtubule severing and neurite outgrowth.
Li S, Liang Y, Zou J, Cai Z, Yang H, Yang J, Zhang Y, Lin H, Zhang G, Tan M., Free PMC Article | 10/22/2022 |
| Katanin P60 and P80 in papillary thyroid carcinoma patients: Indicators for exacerbated tumor features and worse disease-free survival. | Katanin P60 and P80 in papillary thyroid carcinoma patients: Indicators for exacerbated tumor features and worse disease-free survival.
Chen Q, Lin F, Lin E, Huang Q, Wu G., Free PMC Article | 10/23/2021 |
| Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer. | Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer.
Wang L, Tantai J, Zhu X., Free PMC Article | 07/3/2021 |
| A chemical genetics approach to examine the functions of AAA proteins. | A chemical genetics approach to examine the functions of AAA proteins.
Cupido T, Jones NH, Grasso MJ, Pisa R, Kapoor TM., Free PMC Article | 06/26/2021 |
| structures of the apo and ATPgammaS-bound states of the catalytic AAA domain of human katanin p60 at 3.0 and 2.9 A resolution, respectively, are reported. | Structural and Molecular Basis for Katanin-Mediated Severing of Glutamylated Microtubules.
Shin SC, Im SK, Jang EH, Jin KS, Hur EM, Kim EE. | 03/14/2020 |
| In this study, we identified the main regulatory region of KATNA1 gene encoding katanin-p60 as 5' UTR, which has a key role for its expression, and showed Elk1 binding to KATNA1. Furthermore, we identified that Elk1 decreased katanin-p60 and spastin protein expressions, while mRNA levels were increased upon Elk1 overexpression. | Elk1 affects katanin and spastin proteins via differential transcriptional and post-transcriptional regulations.
Kelle D, Kırımtay K, Selçuk E, Karabay A., Free PMC Article | 12/7/2019 |
| targeting an active version of katanin p60 to the kinetochore can reduce the fidelity of achieving full chromosome alignment in metaphase and could serve as a microtubule disruption tool for the future. | Creation and testing of a new, local microtubule-disruption tool based on the microtubule-severing enzyme, katanin p60.
Advani S, Maresca TJ, Ross JL., Free PMC Article | 10/19/2019 |
| CAMSAP3 precisely coordinates with dynein and katanin to regulate the microtubule detachment process. | CAMSAP3 accumulates in the pericentrosomal area and accompanies microtubule release from the centrosome via katanin.
Dong C, Xu H, Zhang R, Tanaka N, Takeichi M, Meng W. | 02/24/2018 |
| ASPM-katanin complex controls microtubule disassembly at spindle poles and that misregulation of this process can lead to microcephaly. | Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.
Jiang K, Rezabkova L, Hua S, Liu Q, Capitani G, Altelaar AFM, Heck AJR, Kammerer RA, Steinmetz MO, Akhmanova A., Free PMC Article | 09/9/2017 |
| Katanin Severing and Binding Microtubules Are Inhibited by Tubulin Carboxy Tails | Katanin Severing and Binding Microtubules Are Inhibited by Tubulin Carboxy Tails.
Bailey ME, Sackett DL, Ross JL., Free PMC Article | 09/24/2016 |
| analysis of spastin's microtubule-binding properties and comparison with katanin | Spastin's microtubule-binding properties and comparison to katanin.
Eckert T, Le DT, Link S, Friedmann L, Woehlke G., Free PMC Article | 06/29/2013 |
| Data propose a model in which spatial rearrangement of the p60 katanin N-terminal domain relative to the C-terminal AAA domain may be important for productive ATP hydrolysis towards MT-severing. | Effect of Ca2+ on the microtubule-severing enzyme p60-katanin. Insight into the substrate-dependent activation mechanism.
Iwaya N, Akiyama K, Goda N, Tenno T, Fujiwara Y, Hamada D, Ikura T, Shirakawa M, Hiroaki H. | 05/19/2012 |
| Katanin p60 was aberrantly expressed during prostate cancer progression. The elevated katanin p60 expression may contribute to cancer cell metastasis via a stimulatory effect on cell motility. | Aberrant expression of katanin p60 in prostate cancer bone metastasis.
Ye X, Lee YC, Choueiri M, Chu K, Huang CF, Tsai WW, Kobayashi R, Logothetis CJ, Yu-Lee LY, Lin SH., Free PMC Article | 03/3/2012 |
| Observational study of gene-disease association. (HuGE Navigator) | Centrosome-related genes, genetic variation, and risk of breast cancer.
Olson JE, Wang X, Pankratz VS, Fredericksen ZS, Vachon CM, Vierkant RA, Cerhan JR, Couch FJ., Free PMC Article | 06/30/2010 |
| A common substrate recognition mode conserved between katanin p60 and VPS4 governs microtubule severing and membrane skeleton reorganization | A common substrate recognition mode conserved between katanin p60 and VPS4 governs microtubule severing and membrane skeleton reorganization.
Iwaya N, Kuwahara Y, Fujiwara Y, Goda N, Tenno T, Akiyama K, Mase S, Tochio H, Ikegami T, Shirakawa M, Hiroaki H., Free PMC Article | 06/28/2010 |
| LAPSER1 C terminal domain inhibits katanin(p80/p60)-mediated microtubule severing in vitro. | LAPSER1/LZTS2: a pluripotent tumor suppressor linked to the inhibition of katanin-mediated microtubule severing.
Sudo H, Maru Y. | 01/21/2010 |