| Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vgamma9Vdelta2 T cells. | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells.
Yuan L, Ma X, Yang Y, Qu Y, Li X, Zhu X, Ma W, Duan J, Xue J, Yang H, Huang JW, Yi S, Zhang M, Cai N, Zhang L, Ding Q, Lai K, Liu C, Zhang L, Liu X, Yao Y, Zhou S, Li X, Shen P, Chang Q, Malwal SR, He Y, Li W, Chen C, Chen CC, Oldfield E, Guo RT, Zhang Y., Free PMC Article | 09/29/2023 |
| Mutations to the BTN2A1 Linker Region Impact Its Homodimerization and Its Cytoplasmic Interaction with Phospho-Antigen-Bound BTN3A1. | Mutations to the BTN2A1 Linker Region Impact Its Homodimerization and Its Cytoplasmic Interaction with Phospho-Antigen-Bound BTN3A1.
Nguyen K, Jin Y, Howell M, Hsiao CC, Wiemer AJ, Vinogradova O., Free PMC Article | 06/26/2023 |
| BTN3A Targeting Vgamma9Vdelta2 T Cells Antimicrobial Activity Against Coxiella burnetii-Infected Cells. | BTN3A Targeting Vγ9Vδ2 T Cells Antimicrobial Activity Against Coxiella burnetii-Infected Cells.
Gay L, Mezouar S, Cano C, Foucher E, Gabriac M, Fullana M, Madakamutil L, Mège JL, Olive D., Free PMC Article | 07/23/2022 |
| BTN2A1, an immune checkpoint targeting Vgamma9Vdelta2 T cell cytotoxicity against malignant cells. | BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells.
Cano CE, Pasero C, De Gassart A, Kerneur C, Gabriac M, Fullana M, Granarolo E, Hoet R, Scotet E, Rafia C, Herrmann T, Imbert C, Gorvel L, Vey N, Briantais A, le Floch AC, Olive D. | 02/12/2022 |
| The intracellular domain of BTN2A1 binds to the intracellular domain of BTN3A1 only in the presence of phosphoantigen. | Ligand-induced interactions between butyrophilin 2A1 and 3A1 internal domains in the HMBPP receptor complex.
Hsiao CC, Nguyen K, Jin Y, Vinogradova O, Wiemer AJ., Free PMC Article | 01/27/2022 |
| Soluble BTN2A1 Is a Potential Prognosis Biomarker in Pre-Treated Advanced Renal Cell Carcinoma. | Soluble BTN2A1 Is a Potential Prognosis Biomarker in Pre-Treated Advanced Renal Cell Carcinoma.
Billon E, Chanez B, Rochigneux P, Albiges L, Vicier C, Pignot G, Walz J, Chretien AS, Gravis G, Olive D., Free PMC Article | 11/6/2021 |
| A comparison of the allele frequencies or genotype distributions by the chi2 test revealed that rs6929846 of BTN2A1 was significantly associated with dyslipidemia. | Association of a polymorphism of BTN2A1 with dyslipidemia in community-dwelling individuals.
Horibe H, Ueyama C, Fujimaki T, Oguri M, Kato K, Ichihara S, Yamada Y. | 09/27/2014 |
| BTN2A1 may be a susceptibility gene for myocardial infarction in Japanese individuals. | Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations.
Yamada Y, Nishida T, Ichihara S, Sawabe M, Fuku N, Nishigaki Y, Aoyagi Y, Tanaka M, Fujiwara Y, Yoshida H, Shinkai S, Satoh K, Kato K, Fujimaki T, Yokoi K, Oguri M, Yoshida T, Watanabe S, Nozawa Y, Hasegawa A, Kojima T, Han BG, Ahn Y, Lee M, Shin DJ, Lee JH, Jang Y. | 07/16/2013 |
| Genetic variants of APOA5 and BTN2A1 may synergistically affect the prevalence of dyslipidemia in East Asian populations and of metabolic syndrome in Japanese individuals. | Synergistic effects of genetic variants of APOA5 and BTN2A1 on dyslipidemia or metabolic syndrome.
Hiramatsu M, Oguri M, Kato K, Horibe H, Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Shin DJ, Lee JH, Jang Y, Yamada Y. | 09/29/2012 |
| BTN2A1 may be a susceptibility gene for Type 2 diabetes in Japanese individuals | Association of a polymorphism of BTN2A1 with type 2 diabetes mellitus in Japanese individuals.
Hiramatsu M, Oguri M, Kato K, Yoshida T, Fujimaki T, Horibe H, Yokoi K, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Murohara T, Yamada Y. | 03/3/2012 |
| Genotype distributions and allele frequencies of the C/T polymorphism (rs6929846) were significantly associated with metabolic syndrome in Japanese subjects, but not in the Korean population. | Association of a genetic variant of BTN2A1 with metabolic syndrome in East Asian populations.
Oguri M, Kato K, Yoshida T, Fujimaki T, Horibe H, Yokoi K, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Shin DJ, Lee JH, Jang Y, Yamada Y. | 02/11/2012 |
| Results suggest that BTN2A1 may be a susceptibility gene for chronic kidney disease in Japanese individuals. | Association of a genetic variant of BTN2A1 with chronic kidney disease in Japanese individuals.
Yoshida T, Kato K, Horibe H, Oguri M, Fukuda M, Satoh K, Aoyagi Y, Shinkai S, Nozawa Y, Yamada Y. | 01/14/2012 |
| BTN2A1 may be a susceptibility gene for hypertension in Japanese individuals, with the T allele being related to high blood pressure. | Association of a polymorphism of BTN2A1 with hypertension in Japanese individuals.
Horibe H, Kato K, Oguri M, Yoshida T, Fujimaki T, Kawamiya T, Yokoi K, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Murohara T, Yamada Y. | 11/26/2011 |
| associations of rs6929846 of butyrophilin subfamily 2 member A1 to myocardial infarction among individuals stratified by the absence or presence of hypertension, diabetes mellitus and chronic kidney disease | Association of polymorphisms of BTN2A1 and ILF3 with myocardial infarction in Japanese individuals with or without hypertension, diabetes mellitus or chronic kidney disease.
Yoshida T, Kato K, Oguri M, Horibe H, Kawamiya T, Yokoi K, Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Yamada Y. | 09/24/2011 |
| The relationship between rs6929846 of BTN2A1 or rs2569512 of ILF3 and myocardial infarction is influenced by the serum concentrations of high density lipoprotein cholesterol and low density lipoprotein cholesterol, respectively. | Association of polymorphisms of BTN2A1 and ILF3 with myocardial infarction in Japanese individuals with different lipid profiles.
Yoshida T, Kato K, Oguri M, Horibe H, Kawamiya T, Yokoi K, Fujimaki T, Watanabe S, Satoh K, Aoyagi Y, Tanaka M, Yoshida H, Shinkai S, Nozawa Y, Yamada Y. | 07/16/2011 |
| Rather than interacting with T cells, butyrophilin BTN2A1 is recognized by DC-SIGN on immature monocyte-derived dendritic cells. | The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN.
Malcherek G, Mayr L, Roda-Navarro P, Rhodes D, Miller N, Trowsdale J. | 01/21/2010 |