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    WIF1 WNT inhibitory factor 1 [ Homo sapiens (human) ]

    Gene ID: 11197, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Upregulated miR-374a-5p drives psoriasis pathogenesis through WIF1 downregulation and Wnt5a/NF-kappaB activation.

    Upregulated miR-374a-5p drives psoriasis pathogenesis through WIF1 downregulation and Wnt5a/NF-κB activation.
    Ma J, Gan L, Chen H, Chen L, Hu Y, Luan C, Chen K, Zhang J.

    06/13/2024
    Expanding the histological spectrum of salivary gland neoplasms with HMGA2::WIF1 fusion emphasising their malignant potential: a report of eight cases.

    Expanding the histological spectrum of salivary gland neoplasms with HMGA2::WIF1 fusion emphasising their malignant potential: a report of eight cases.
    Katabi N, Sukhadia P, DiNapoli SE, Weinreb I, Hahn E, Ghossein R, Xu B.,

    12/28/2023
    WIF1 was downregulated in cervical cancer due to promoter methylation.

    WIF1 was downregulated in cervical cancer due to promoter methylation.
    Wang Y, Yuan S, Ma J, Liu H, Huang L, Zhang F, Wang X.

    06/21/2023
    HMGA2-WIF1 Rearrangements Characterize a Distinctive Subset of Salivary Pleomorphic Adenomas With Prominent Trabecular (Canalicular Adenoma-like) Morphology.

    HMGA2-WIF1 Rearrangements Characterize a Distinctive Subset of Salivary Pleomorphic Adenomas With Prominent Trabecular (Canalicular Adenoma-like) Morphology.
    Agaimy A, Ihrler S, Baněčková M, Costés Martineau V, Mantsopoulos K, Hartmann A, Iro H, Stoehr R, Skálová A.

    02/19/2022
    The complex role of Wnt ligands in type 2 diabetes mellitus and related complications.

    The complex role of Wnt ligands in type 2 diabetes mellitus and related complications.
    Nie X, Wei X, Ma H, Fan L, Chen WD., Free PMC Article

    02/5/2022
    Wnt Inhibitory Factor 1 Binds to and Inhibits the Activity of Sonic Hedgehog.

    Wnt Inhibitory Factor 1 Binds to and Inhibits the Activity of Sonic Hedgehog.
    Kerekes K, Trexler M, Bányai L, Patthy L., Free PMC Article

    01/8/2022
    Prognostic Role of RASSF1A, SOX17 and Wif-1 Promoter Methylation Status in Cell-Free DNA of Advanced Gastric Cancer Patients.

    Prognostic Role of RASSF1A, SOX17 and Wif-1 Promoter Methylation Status in Cell-Free DNA of Advanced Gastric Cancer Patients.
    Karamitrousis EI, Balgkouranidou I, Xenidis N, Amarantidis K, Biziota E, Koukaki T, Trypsianis G, Karayiannakis A, Bolanaki H, Kolios G, Lianidou E, Kakolyris S., Free PMC Article

    12/4/2021
    The detection of specific hypermethylated WIF1 and NPY genes in circulating DNA by crystal digital PCR is a powerful new tool for colorectal cancer diagnosis and screening.

    The detection of specific hypermethylated WIF1 and NPY genes in circulating DNA by crystal digital PCR™ is a powerful new tool for colorectal cancer diagnosis and screening.
    Overs A, Flammang M, Hervouet E, Bermont L, Pretet JL, Christophe B, Selmani Z., Free PMC Article

    10/23/2021
    Association of ZNF331 and WIF1 methylation in peripheral blood leukocytes with the risk and prognosis of gastric cancer.

    Association of ZNF331 and WIF1 methylation in peripheral blood leukocytes with the risk and prognosis of gastric cancer.
    Nie C, Han X, Wei R, Leonteva A, Hong J, Du X, Wang J, Zhu L, Zhao Y, Xue Y, Zhou H, Tian W., Free PMC Article

    10/23/2021
    Association between SOX17, Wif-1 and RASSF1A promoter methylation status and response to chemotherapy in patients with metastatic gastric cancer.

    Association between SOX17, Wif-1 and RASSF1A promoter methylation status and response to chemotherapy in patients with metastatic gastric cancer.
    Karamitrousis E, Balgkouranidou I, Xenidis N, Amarantidis K, Biziota E, Koukaki T, Trypsianis G, Karayiannakis A, Bolanaki H, Chatzaki E, Kolios G, Lianidou E, Lambropoulou M, Kakolyris S.

    09/25/2021
    SPRR2C, DEFB4A, WIF1, CRY2, and KRT19 are correlated with the development of atopic eczema.

    SPRR2C, DEFB4A, WIF1, CRY2, and KRT19 are correlated with the development of atopic eczema.
    Yu YW, Li YF, Jiang M, Zhao JJ.

    09/18/2021
    Gene Methylation and Silencing of WIF1 Is a Frequent Genetic Abnormality in Mantle Cell Lymphoma.

    Gene Methylation and Silencing of WIF1 Is a Frequent Genetic Abnormality in Mantle Cell Lymphoma.
    Alshareef A, Peters AC, Gélébart P, Chen W, Lai R., Free PMC Article

    09/11/2021
    LINC00176 facilitates CD4(+)T cell adhesion in systemic lupus erythematosus via the WNT5a signaling pathway by regulating WIF1.

    LINC00176 facilitates CD4(+)T cell adhesion in systemic lupus erythematosus via the WNT5a signaling pathway by regulating WIF1.
    Lu C, Shao X, Zhou S, Pan C.

    07/31/2021
    The status of WIF1 methylation in cell-free DNA is associated with the insusceptibility for gefitinib in the treatment of lung cancer.

    The status of WIF1 methylation in cell-free DNA is associated with the insusceptibility for gefitinib in the treatment of lung cancer.
    Shen Z, Chen C, Sun J, Huang J, Liu S.

    07/10/2021
    A long non-coding RNA, HOTAIR, promotes cartilage degradation in osteoarthritis by inhibiting WIF-1 expression and activating Wnt pathway.

    A long non-coding RNA, HOTAIR, promotes cartilage degradation in osteoarthritis by inhibiting WIF-1 expression and activating Wnt pathway.
    Yang Y, Xing D, Wang Y, Jia H, Li B, Li JJ., Free PMC Article

    02/6/2021
    DNA methylation and gene expression of sFRP2, sFRP4, Dkk 1, and Wif1 during osteoblastic differentiation of bone marrow derived mesenchymal stem cells.

    DNA methylation and gene expression of sFRP2, sFRP4, Dkk 1, and Wif1 during osteoblastic differentiation of bone marrow derived mesenchymal stem cells.
    Mashhadikhan M, Kheiri H, Dehghanifard A.

    02/2/2021
    m(6)A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling.

    m(6)A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling.
    Tang B, Yang Y, Kang M, Wang Y, Wang Y, Bi Y, He S, Shimamoto F., Free PMC Article

    01/16/2021
    MiR-374a Activates Wnt/beta-Catenin Signaling to Promote Osteosarcoma Cell Migration by Targeting WIF-1.

    MiR-374a Activates Wnt/β-Catenin Signaling to Promote Osteosarcoma Cell Migration by Targeting WIF-1.
    Li W, Meng Z, Zou T, Wang G, Su Y, Yao S, Sun X.

    01/16/2021
    polymorphism rs3782499 of WIF1 gene is a functional variant regulating the expression of WIF1 in DDH (developmental dysplasia of the hip) in Chinese Han population, which might be a potential biomarker for the early diagnosis of DDH

    Genetic variant of WIF1 gene is functionally associated with developmental dysplasia of the hip in Han Chinese population.
    Sun Y, You Y, Dai K, Zhang J, Yan M, Zhang Y., Free PMC Article

    06/27/2020
    WIF1 gene was hypermethylated in tumor tissues of postoperative CRC pateints.

    DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patients.
    Liu X, Fu J, Bi H, Ge A, Xia T, Liu Y, Sun H, Li D, Zhao Y., Free PMC Article

    05/30/2020
    Ihh is a marker for poor prognosis in patients with lung squamous cell carcinoma and adenocarcinoma. WIF-1 is not a predictive marker for lung cancer.

    WIF-1 and Ihh Expression and Clinical Significance in Patients With Lung Squamous Cell Carcinoma and Adenocarcinoma.
    Zhang Y, Hu C.

    07/27/2019
    a significant correlation between pituitary adenoma invasion and low expression of WIF1 and sFRP4 is reported.

    Aberrant expression of the sFRP and WIF1 genes in invasive non-functioning pituitary adenomas.
    Song W, Qian L, Jing G, Jie F, Xiaosong S, Chunhui L, Yangfang L, Guilin L, Gao H, Yazhuo Z.

    05/11/2019
    this study showed elevated WIF-1 expression as tissue damage and inflammation progressed in inflammatory bowel disease

    Expression of WIF-1 in inflammatory bowel disease.
    Terry R, Chintanaboina J, Patel D, Lippert B, Haner M, Price K, Tracy A, Lalos A, Wakeley M, Gutierrez LS.

    05/11/2019
    MicroRNA-552 promotes hepatocellular carcinoma progression by downregulating WIF1

    MicroRNA-552 promotes hepatocellular carcinoma progression by downregulating WIF1.
    Li C, Wang Z, Chen S, Zhang J, Qu K, Liu C., Free PMC Article

    02/23/2019
    expression of TGF-beta1 and WIF1 in nonfunctioning pituitary adenomas correlated with cell proliferation and recurrence potential

    Association of TGF-β1 and WIF1 Expression with 36 Paired Primary/Recurrent Nonfunctioning Pituitary Adenomas: A High-Throughput Tissue Microarrays Immunohistochemical Study.
    Zhu H, Yao X, Wu L, Li C, Bai J, Gao H, Ji H, Zhang Y.

    02/9/2019
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