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    OIP5 Opa interacting protein 5 [ Homo sapiens (human) ]

    Gene ID: 11339, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    beta-TrCP-Mediated Proteolysis of Mis18beta Prevents Mislocalization of CENP-A and Chromosomal Instability.

    β-TrCP-Mediated Proteolysis of Mis18β Prevents Mislocalization of CENP-A and Chromosomal Instability.
    Sethi SC, Shrestha RL, Balachandra V, Durairaj G, Au WC, Nirula M, Karpova TS, Kaiser P, Basrai MA., Free PMC Article

    10/16/2024
    [H3K27 acetylation promotes lncRNA OIP5-AS1 transcription and induces apoptosis of nasal epithelial cells in allergic rhinitis through up-regulation of TLR4].

    [H3K27 acetylation promotes lncRNA OIP5-AS1 transcription and induces apoptosis of nasal epithelial cells in allergic rhinitis through up-regulation of TLR4].
    Xie Y, She Z, Li R, Wu R, Wang R, Liu J.

    06/24/2024
    The role of OIP5 in the carcinogenesis and progression of ovarian cancer.

    The role of OIP5 in the carcinogenesis and progression of ovarian cancer.
    Zhang X, Gu W, Lin A, Duan R, Lian L, Huang Y, Li T, Sun Q., Free PMC Article

    09/7/2023
    Opa interacting protein 5 promotes proliferation and migration of trophoblast cells via activating STAT3 pathway.

    Opa interacting protein 5 promotes proliferation and migration of trophoblast cells via activating STAT3 pathway.
    Xu H, Wang J, Liu J, Huang J.

    06/18/2022
    Long non-coding RNA Opa interacting protein 5-antisense RNA 1 binds to micorRNA-34a to upregulate oncogenic PD-L1 in non-small cell lung cancer.

    Long non-coding RNA Opa interacting protein 5-antisense RNA 1 binds to micorRNA-34a to upregulate oncogenic PD-L1 in non-small cell lung cancer.
    Qiao X, Zhao F., Free PMC Article

    04/23/2022
    Characterization of Opa interacting protein 5 as a new biomarker and therapeutic target for oral cancer.

    Characterization of Opa interacting protein 5 as a new biomarker and therapeutic target for oral cancer.
    Zhu M, Takano A, Tsevegjav B, Yoshitake Y, Shinohara M, Daigo Y.

    03/26/2022
    OIP5-AS1 specifies p53-driven POX transcription regulated by TRPC6 in glioma.

    OIP5-AS1 specifies p53-driven POX transcription regulated by TRPC6 in glioma.
    Shao W, Hao ZY, Chen YF, Du J, He Q, Ren LL, Gao Y, Song N, Song Y, He H, Wang YZ., Free PMC Article

    02/19/2022
    Inhibitory role of long non-coding RNA OIP5-AS1 in rheumatoid arthritis progression through the microRNA-448-paraoxonase 1-toll-like receptor 3-nuclear factor kappaB axis.

    Inhibitory role of long non-coding RNA OIP5-AS1 in rheumatoid arthritis progression through the microRNA-448-paraoxonase 1-toll-like receptor 3-nuclear factor κB axis.
    Qing P, Liu Y.

    10/23/2021
    Long Non-Coding RNA OIP5-AS1 Inhibits the Proliferation and Migration of Esophageal Squamous Carcinoma Cells by Targeting FOXD1/miR-30a-5p Axis and the Effect of Micro- and Nano-Particles on Targeting Transfection System.

    Long Non-Coding RNA OIP5-AS1 Inhibits the Proliferation and Migration of Esophageal Squamous Carcinoma Cells by Targeting FOXD1/miR-30a-5p Axis and the Effect of Micro- and Nano-Particles on Targeting Transfection System.
    Yan Q, Liu L, Yang H, Xu C, Wang Z, Wang Q, Wu Z, Wu C, Dong L, Wang J, Wu M.

    09/25/2021
    LncRNA OIP5-AS1 affects the biological behaviors of chondrocytes of patients with osteoarthritis by regulating micro-30a-5p.

    LncRNA OIP5-AS1 affects the biological behaviors of chondrocytes of patients with osteoarthritis by regulating micro-30a-5p.
    Qin GH, Yang WC, Yao JN, Zhao Y, Wu XJ.

    09/18/2021
    Long non-coding RNA OIP5-AS1 promotes the growth of gastric cancer through the miR-367-3p/HMGA2 axis.

    Long non-coding RNA OIP5-AS1 promotes the growth of gastric cancer through the miR-367-3p/HMGA2 axis.
    Tao Y, Wan X, Fan Q, Wang Y, Sun H, Ma L, Sun C, Wu Y.

    07/24/2021
    Opa-Interacting Protein 5 Expression in Human Glioma Tissues Is Essential to the Biological Function of U251 Human Malignant Glioma Cells.

    Opa-Interacting Protein 5 Expression in Human Glioma Tissues Is Essential to the Biological Function of U251 Human Malignant Glioma Cells.
    Chen L, Wang R, Gao L, Shi W., Free PMC Article

    07/17/2021
    LncRNA OIP5-AS1 facilitates ox-LDL-induced endothelial cell injury through the miR-98-5p/HMGB1 axis.

    LncRNA OIP5-AS1 facilitates ox-LDL-induced endothelial cell injury through the miR-98-5p/HMGB1 axis.
    Zheng Z, Zhang G, Liang X, Li T.

    07/17/2021
    Lnc-OIP5-AS1 exacerbates aorta wall injury during the development of aortic dissection through upregulating TUB via sponging miR-143-3p.

    Lnc-OIP5-AS1 exacerbates aorta wall injury during the development of aortic dissection through upregulating TUB via sponging miR-143-3p.
    Wang P, Wang Z, Zhang M, Wu Q, Shi F.

    03/20/2021
    OIP5-AS1 promotes the progression of gastric cancer cells via the miR-153-3p/ZBTB2 axis.

    OIP5-AS1 promotes the progression of gastric cancer cells via the miR-153-3p/ZBTB2 axis.
    Zhi XH, Jiang K, Ma YY, Zhou LQ.

    03/20/2021
    The upregulation of OIP5 mRNA was observed in nasopharyngeal carcinoma (NPC) tissues from two Gene Expression Omnibus datasets. Expression of OIP5 mRNA was significantly upregulated in several NPC cell lines compared to normal nasopharyngeal cells. Knockdown of OIP5 remarkably decreased the expression of p-JAK2 and p-STAT3 protein in NPC cells. Data indicated that OIP5 promoted NPC progression by modulating JAK2/STAT3.

    Opa interacting protein 5 promotes metastasis of nasopharyngeal carcinoma cells by promoting EMT via modulation of JAK2/STAT3 signal.
    Zheng YQ, Cui YR, Yang S, Wang YP, Qiu YJ, Hu WL.

    07/25/2020
    FN1 expression was regulated by the oncogenic long noncoding RNA (lncRNA) OIP5-AS1 through sponging miR-200b-3p.

    Fibronectin-1 modulated by the long noncoding RNA OIP5-AS1/miR-200b-3p axis contributes to doxorubicin resistance of osteosarcoma cells.
    Kun-Peng Z, Chun-Lin Z, Xiao-Long M, Lei Z.

    04/4/2020
    This study showed the role of Lactobacilli in down-regulation of TSGA10, AURKC, OIP5 and AKAP4 genes. Such expression change might be involved in the anticancer effects of these Lactobacilli. The underlying mechanisms of these observations are not clear but epigenetic modulatory mechanisms may participate in this process.

    Down-regulation of TSGA10, AURKC, OIP5 and AKAP4 genes by Lactobacillus rhamnosus GG and Lactobacillus crispatus SJ-3C-US supernatants in HeLa cell line.
    Nouri Z, Neyazi N, Modarressi, Karami F, Abedin-Do A, Taherian-Esfahani Z, Ghafouri-Fard S, Motevaseli E.

    09/7/2019
    the overall results demonstrated the involvement of OIP5 in the progression of liver cancer and its mechanism of action.

    Overexpression of Opa interacting protein 5 increases the progression of liver cancer via BMPR2/JUN/CHEK1/RAC1 dysregulation.
    Li Y, Xiao F, Li W, Hu P, Xu R, Li J, Li G, Zhu C., Free PMC Article

    07/6/2019
    E3 ubiquitin ligase RNF123 targets LMNB1, Rb protein and LAP2alpha for proteasomal degradation.

    E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.
    Khanna R, Krishnamoorthy V, Parnaik VK.

    04/13/2019
    OIP5 knockdown rescues glioma cells following lomustine treatment.

    OIP5 Expression Sensitize Glioblastoma Cells to Lomustine Treatment.
    Rodrigues-Junior DM, Biassi TP, Carlin V, Buri MV, Torrecilhas AC, Bortoluci KR, Vettore AL.

    01/26/2019
    LncRNA OIP5-AS1 suppressed cell viability, promoted radio-induced apoptosis, and enhanced the radiosensitivity of CRC cells by regulating DYRK1A expression through miR-369-3p.

    LncRNA OIP5-AS1 regulates radioresistance by targeting DYRK1A through miR-369-3p in colorectal cancer cells.
    Zou Y, Yao S, Chen X, Liu D, Wang J, Yuan X, Rao J, Xiong H, Yu S, Yuan X, Zhu F, Hu G, Wang Y, Xiong H.

    10/27/2018
    LncRNA OIP5-AS1 modulated the expression of Bcl-2 by targeting miR-448 in lung adenocarcinoma cells.

    Long non-coding RNA OIP5-AS1 functions as an oncogene in lung adenocarcinoma through targeting miR-448/Bcl-2.
    Deng J, Deng H, Liu C, Liang Y, Wang S.

    08/18/2018
    interaction network might function as an oncogene in bladder cancer progression

    Exploration of the pathways and interaction network involved in bladder cancer cell line with knockdown of Opa interacting protein 5.
    He X, Ding X, Wen D, Hou J, Ping J, He J.

    06/2/2018
    The authors demonstrate that CDK1 controls Mis18 complex recruitment to centromeres by regulating oligomerization of M18BP1 through the Mis18alpha:Mis18beta scaffold.

    CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading.
    Pan D, Klare K, Petrovic A, Take A, Walstein K, Singh P, Rondelet A, Bird AW, Musacchio A., Free PMC Article

    02/10/2018
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