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    Dao D-amino-acid oxidase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 114027, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Evaluation of D-amino acid oxidase activity in rat kidney using a D-kynurenine derivative, 6-methylthio-D-kynurenine: An in vivo microdialysis study.

    Evaluation of D-amino acid oxidase activity in rat kidney using a D-kynurenine derivative, 6-methylthio-D-kynurenine: An in vivo microdialysis study.
    Fukushima T, Kansaku A, Umino M, Sakamoto T, Onozato M.

    01/16/2024
    Overexpression of D-amino acid oxidase prevents retinal neurovascular pathologies in diabetic rats.

    Overexpression of D-amino acid oxidase prevents retinal neurovascular pathologies in diabetic rats.
    Jiang H, Zhang H, Jiang X, Wu S.

    02/19/2022
    d-Amino acid oxidase deficiency is caused by a large deletion in the Dao gene in LEA rats.

    d-Amino acid oxidase deficiency is caused by a large deletion in the Dao gene in LEA rats.
    Shimizu Y, Ishii C, Yanobu-Takanashi R, Nakano K, Imaike A, Mita M, Hamase K, Okamura T.

    10/31/2020
    Plasma DAO activity decreases in response to severe intestinal mucosal injury after 5-FU treatment.

    Diamine oxidase as a marker of intestinal mucosal injury and the effect of soluble dietary fiber on gastrointestinal tract toxicity after intravenous 5-fluorouracil treatment in rats.
    Fukudome I, Kobayashi M, Dabanaka K, Maeda H, Okamoto K, Okabayashi T, Baba R, Kumagai N, Oba K, Fujita M, Hanazaki K.

    02/7/2015
    Its toxic effect on motor neurons can be mediated by expression in motor neurons and it promotes autophagy.

    Pathogenic effects of amyotrophic lateral sclerosis-linked mutation in D-amino acid oxidase are mediated by D-serine.
    Paul P, Murphy T, Oseni Z, Sivalokanathan S, de Belleroche JS.

    10/4/2014
    The study showed that the operation of renal ischemia resulted in a 45.49 +/- 8.30% (n = 8) decrease in the DAAO-induced consumption of substrate, indicating a sharp decrease in renal DAAO activity following this acute renal injury.

    Study on the decrease of renal D-amino acid oxidase activity in the rat after renal ischemia by chiral ligand exchange capillary electrophoresis.
    Zhang H, Qi L, Lin Y, Mao L, Chen Y.

    04/28/2012
    D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.

    D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
    Popiolek M, Ross JF, Charych E, Chanda P, Gundelfinger ED, Moss SJ, Brandon NJ, Pausch MH., Free PMC Article

    10/22/2011
    Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase

    Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase.
    Mitchell J, Paul P, Chen HJ, Morris A, Payling M, Falchi M, Habgood J, Panoutsou S, Winkler S, Tisato V, Hajitou A, Smith B, Vance C, Shaw C, Mazarakis ND, de Belleroche J., Free PMC Article

    05/31/2010
    results suggest that an increase in DAO expression in parts of the brain is involved in aberrant D-amino acid metabolism, may be a potential therapeutic target for schizophrenia

    Potential pathophysiological role of D-amino acid oxidase in schizophrenia: immunohistochemical and in situ hybridization study of the expression in human and rat brain.
    Ono K, Shishido Y, Park HK, Kawazoe T, Iwana S, Chung SP, Abou El-Magd RM, Yorita K, Okano M, Watanabe T, Sano N, Bando Y, Arima K, Sakai T, Fukui K.

    01/21/2010
    These results suggest that the TAA repeats are important for expression of the D-amino-acid oxidase gene.

    Mutant rat strain lacking D-amino-acid oxidase.
    Konno R, Okamura T, Kasai N, Summer KH, Niwa A.

    01/21/2010
    This result clearly revealed that DAO was indispensable for the process of chiral inversion of d-leucine.

    Role of renal D-amino-acid oxidase in pharmacokinetics of D-leucine.
    Hasegawa H, Matsukawa T, Shinohara Y, Konno R, Hashimoto T.

    01/21/2010
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