ERK1/2 Regulates Epileptic Seizures by Modulating the DRP1-Mediated Mitochondrial Dynamic. | ERK1/2 Regulates Epileptic Seizures by Modulating the DRP1-Mediated Mitochondrial Dynamic. Chen T, Yang J, Zheng Y, Zhou X, Huang H, Zhang H, Xu Z. | 09/26/2024 |
AKAP1 alleviates VSMC phenotypic modulation and neointima formation by inhibiting Drp1-dependent mitochondrial fission. | AKAP1 alleviates VSMC phenotypic modulation and neointima formation by inhibiting Drp1-dependent mitochondrial fission. Sun J, Shao Y, Pei L, Zhu Q, Yu X, Yao W. | 07/18/2024 |
STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells. | STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells. Zhang H, Chen L, Li J, Sun J, Zhao Q, Wang S, Li G., Free PMC Article | 06/28/2024 |
A partial Drp1 knockout improves autophagy flux independent of mitochondrial function. | A partial Drp1 knockout improves autophagy flux independent of mitochondrial function. Fan RZ, Sportelli C, Lai Y, Salehe SS, Pinnell JR, Brown HJ, Richardson JR, Luo S, Tieu K., Free PMC Article | 03/22/2024 |
Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation. | Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation. Dubois M, Boulghobra D, Rochebloine G, Pallot F, Yehya M, Bornard I, Gayrard S, Coste F, Walther G, Meyer G, Gaillard JC, Armengaud J, Alpha-Bazin B, Reboul C., Free PMC Article | 02/27/2024 |
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation. | Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation. Liu J, Chen Y, Chen H, Wang Y, Li D, Zhang Q, Chai L, Qiu Y, Zhang J, Shen N, Wang Q, Wang J, Li M., Free PMC Article | 09/8/2023 |
Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy. | Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy. Mukherjee R, Tetri LH, Li SJ, Fajardo G, Ostberg NP, Tsegay KB, Gera K, Cornell TT, Bernstein D, Mochly-Rosen D, Haileselassie B., Free PMC Article | 08/11/2023 |
Role of KLF4/NDRG1/DRP1 axis in hypoxia-induced pulmonary hypertension. | Role of KLF4/NDRG1/DRP1 axis in hypoxia-induced pulmonary hypertension. Liu Y, Luo Y, Shi X, Lu Y, Li H, Fu G, Li X, Shan L. | 08/9/2023 |
PINK1 Phosphorylates Drp1(S616) to Improve Mitochondrial Fission and Inhibit the Progression of Hypertension-Induced HFpEF. | PINK1 Phosphorylates Drp1(S616) to Improve Mitochondrial Fission and Inhibit the Progression of Hypertension-Induced HFpEF. Shou J, Huo Y., Free PMC Article | 10/22/2022 |
Swimming Exercise Alleviates Endothelial Mitochondrial Fragmentation via Inhibiting Dynamin-Related Protein-1 to Improve Vascular Function in Hypertension. | Swimming Exercise Alleviates Endothelial Mitochondrial Fragmentation via Inhibiting Dynamin-Related Protein-1 to Improve Vascular Function in Hypertension. Li G, Xu K, Xing W, Yang H, Li Y, Wang X, Zhou J, An J, Dong L, Zhang X, Wang L, Li J, Gao F. | 09/24/2022 |
Chronic exposure to ozone induces cardiac antioxidant response and overexpression of either mitochondrial fision protein DRP1 and hipertrophyc-related proteins. | Chronic exposure to ozone induces cardiac antioxidant response and overexpression of either mitochondrial fision protein DRP1 and hipertrophyc-related proteins. Gómez-Crisóstomo NP, Rivas-Arancibia S, Rodríguez-Martínez E, De la Cruz-Hernández EN, de María Márquez Álvarez C, Estrada Caraveo PA, Gelista Herrera N, Valdés-Fuentes M, Martínez-Abundis E. | 07/23/2022 |
CDK5 Mediates Proinflammatory Effects of Microglia through Activated DRP1 Phosphorylation in Rat Model of Intracerebral Hemorrhage. | CDK5 Mediates Proinflammatory Effects of Microglia through Activated DRP1 Phosphorylation in Rat Model of Intracerebral Hemorrhage. He M, Wang X, Liu Z, Cui Q, Chen Y, Geng W, Zhu J, Shen J., Free PMC Article | 07/23/2022 |
Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis. | Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis. Zhang MY, Zhu L, Bao X, Xie TH, Cai J, Zou J, Wang W, Gu S, Li Y, Li HY, Yao Y, Wei TT. | 06/25/2022 |
Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy. | Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy. Wu H, Li G, Chen W, Luo W, Yang Z, You Z, Zou Y. | 04/16/2022 |
Bone marrow mesenchymal stem cell-derived exosomes inhibit chondrocyte apoptosis and the expression of MMPs by regulating Drp1-mediated mitophagy. | Bone marrow mesenchymal stem cell-derived exosomes inhibit chondrocyte apoptosis and the expression of MMPs by regulating Drp1-mediated mitophagy. Tang S, Tang T, Gao G, Wei Q, Sun K, Huang W. | 03/26/2022 |
N-acetyl-L-cysteine ameliorates mitochondrial dysfunction in ischemia/reperfusion injury via attenuating Drp-1 mediated mitochondrial autophagy. | N-acetyl-L-cysteine ameliorates mitochondrial dysfunction in ischemia/reperfusion injury via attenuating Drp-1 mediated mitochondrial autophagy. Ali M, Tabassum H, Alam MM, Parvez S. | 02/26/2022 |
Decreased dynamin-related protein 1-related mitophagy induces myocardial apoptosis in the aging heart. | Decreased dynamin-related protein 1-related mitophagy induces myocardial apoptosis in the aging heart. Wei X, Wu YE, Wang W, Zhang S, Liu D, Liu H. | 02/12/2022 |
High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy. | High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy. Wu QR, Zheng DL, Liu PM, Yang H, Li LA, Kuang SJ, Lai YY, Rao F, Xue YM, Lin JJ, Liu SX, Chen CB, Deng CY., Free PMC Article | 09/18/2021 |
Drp1-mediated mitochondrial fission is involved in oxidized low-density lipoprotein-induced AF cella poptosis. | Drp1-mediated mitochondrial fission is involved in oxidized low-density lipoprotein-induced AF cella poptosis. Wu W, Jing D, Huang X, Yang W, Shao Z. | 09/11/2021 |
Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain. | Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain. Patel B, New LE, Griffiths JC, Deuchars J, Filippi BM., Free PMC Article | 09/4/2021 |
CaMK II -induced Drp1 phosphorylation contributes to blue light-induced AIF-mediated necroptosis in retinal R28 cells. | CaMK II -induced Drp1 phosphorylation contributes to blue light-induced AIF-mediated necroptosis in retinal R28 cells. Yang D, Rong R, Yang R, You M, Wang M, Li H, Ji D. | 08/28/2021 |
ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension. | ERK/Drp1-dependent mitochondrial fission contributes to HMGB1-induced autophagy in pulmonary arterial hypertension. Feng W, Wang J, Yan X, Zhang Q, Chai L, Wang Q, Shi W, Chen Y, Liu J, Qu Z, Li S, Xie X, Li M., Free PMC Article | 06/19/2021 |
CDK4 and CDK5 Inhibition Have Comparable Mild Hypothermia Effects in Preventing Drp1-Dependent Mitochondrial Fission and Neuron Death Induced by MPP(). | CDK4 and CDK5 Inhibition Have Comparable Mild Hypothermia Effects in Preventing Drp1-Dependent Mitochondrial Fission and Neuron Death Induced by MPP(). Yang SH, Huang CY, Hsieh CY, Chuang JI. | 06/12/2021 |
Cardiac Mitochondrial PTEN-L determines cell fate between apoptosis and survival during chronic alcohol consumption. | Cardiac Mitochondrial PTEN-L determines cell fate between apoptosis and survival during chronic alcohol consumption. Sivakumar A, Shanmugarajan S, Subbiah R, Balakrishnan R. | 06/5/2021 |
Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy. | Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy. Rong R, Xia X, Peng H, Li H, You M, Liang Z, Yao F, Yao X, Xiong K, Huang J, Zhou R, Ji D., Free PMC Article | 05/1/2021 |