| LINC00460 Facilitates Cell Proliferation and Inhibits Ferroptosis in Breast Cancer Through the miR-320a/MAL2 Axis. | LINC00460 Facilitates Cell Proliferation and Inhibits Ferroptosis in Breast Cancer Through the miR-320a/MAL2 Axis.
Zhang C, Xu L, Li X, Chen Y, Shi T, Wang Q., Free PMC Article | 03/24/2023 |
| The novel circ_0084904/miR-802/MAL2 axis promotes the development of cervical cancer. | The novel circ_0084904/miR-802/MAL2 axis promotes the development of cervical cancer.
Chen L, Li H, Yao D, Zou Q, Yu W, Zhou L. | 03/12/2022 |
| MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation. | MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation.
Fang Y, Wang L, Wan C, Sun Y, Van der Jeught K, Zhou Z, Dong T, So KM, Yu T, Li Y, Eyvani H, Colter AB, Dong E, Cao S, Wang J, Schneider BP, Sandusky GE, Liu Y, Zhang C, Lu X, Zhang X., Free PMC Article | 09/11/2021 |
| MAL2 interacts with IQGAP1 to promote pancreatic cancer progression by increasing ERK1/2 phosphorylation. | MAL2 interacts with IQGAP1 to promote pancreatic cancer progression by increasing ERK1/2 phosphorylation.
Zhang B, Xiao J, Cheng X, Liu T. | 07/17/2021 |
| RP11-284F21.9 knockdown could reduce MAL2 expression, while miR-383-5p inhibitors abolished this repressive effect | RP11-284F21.9 promotes oral squamous cell carcinoma development via the miR-383-5p/MAL2 axis.
Shao B, Fu X, Li X, Li Y, Gan N. | 02/1/2020 |
| MAL2 has a role in promoting proliferation, migration, and invasion through regulating epithelial-mesenchymal transition in breast cancer cell lines | MAL2 promotes proliferation, migration, and invasion through regulating epithelial-mesenchymal transition in breast cancer cell lines.
Bhandari A, Shen Y, Sindan N, Xia E, Gautam B, Lv S, Zhang X. | 03/30/2019 |
| Up-regulation of MAL2 was hound in papillary thyroid gland tissues and significantly correlated with poor overall survival. | MiR-129 regulates growth and invasion by targeting MAL2 in papillary thyroid carcinoma.
Gao X, Chen Z, Li A, Zhang X, Cai X. | 11/3/2018 |
| data suggested that MAL2 and TPD52 might be potential biomarkers for clinical prognosis and might be a promising therapeutic target for CRC | The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) are highly expressed in colorectal cancer and correlated with poor prognosis.
Li J, Li Y, Liu H, Liu Y, Cui B., Free PMC Article | 09/30/2017 |
| MAL2 and STK16 function to sort secretory soluble cargo into the constitutive secretory pathway in hepatocytes. | Serine/threonine kinase 16 and MAL2 regulate constitutive secretion of soluble cargo in hepatic cells.
In JG, Striz AC, Bernad A, Tuma PL., Free PMC Article | 11/22/2014 |
| Results prove for the first time the interaction of PLP and MAL2 in oligodendrocytic cells, supporting the transcytotic model of PLP transport previously suggested. | Interaction of PLP with GFP-MAL2 in the human oligodendroglial cell line HOG.
Bello-Morales R, Pérez-Hernández M, Rejas MT, Matesanz F, Alcina A, López-Guerrero JA., Free PMC Article | 10/29/2011 |
| MAL2 overexpression was highest in serous carcinomas relative to other histological subtypes of ovarian cancer. | MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome.
Byrne JA, Maleki S, Hardy JR, Gloss BS, Murali R, Scurry JP, Fanayan S, Emmanuel C, Hacker NF, Sutherland RL, Defazio A, O'Brien PM., Free PMC Article | 02/5/2011 |
| after differentiation, murine oligodendrocyte precursor and human oligodendroglioma derived cell lines up-regulate the expression of MAL2 and accumulate it in an intracellular compartment, exhibiting a peri-centrosomal localization. | Characterization of the MAL2-positive compartment in oligodendrocytes.
Bello-Morales R, de Marco MC, Aranda JF, Matesanz F, Alcina A, López-Guerrero JA. | 01/25/2010 |
| a role for MAL2 in regulating tumor-associated protein mucin expression and/or localisation | Mucin 1 (MUC1) is a novel partner for MAL2 in breast carcinoma cells.
Fanayan S, Shehata M, Agterof AP, McGuckin MA, Alonso MA, Byrne JA., Free PMC Article | 01/21/2010 |
| The MAL2 gene was shown to effectively separate these two tumor(chromophobe renal cell carcinoma (RCC) and benign oncocytoma) groups by quantitative reverse transcription-PCR using fresh tissue samples, with similar trends seen on formalin-fixed tissues. | Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes.
Rohan S, Tu JJ, Kao J, Mukherjee P, Campagne F, Zhou XK, Hyjek E, Alonso MA, Chen YT. | 01/21/2010 |
| The results indicate that MAL2 protein genes are not ubiquitously expressed in leukemic bone marrow in children, and that RNA sample parameters may influence measures of gene expression more than commonly appreciated. | Expression of tumor protein D52-like genes in childhood leukemia at diagnosis: clinical and sample considerations.
Barbaric D, Byth K, Dalla-Pozza L, Byrne JA. | 01/21/2010 |
| MAL2 protein mRNA species were detected in the thyroid and immunohistochemical analysis of thyroid follicles indicated that MAL2 distributed to the apical membrane | Expression and distribution of MAL2, an essential element of the machinery for basolateral-to-apical transcytosis, in human thyroid epithelial cells.
Marazuela M, Martín-Belmonte F, García-López MA, Aranda JF, de Marco MC, Alonso MA. | 01/21/2010 |
| Data show that MAL2 is essential for transcytosis in HepG2 cells. | MAL2, a novel raft protein of the MAL family, is an essential component of the machinery for transcytosis in hepatoma HepG2 cells.
de Marco MC, Martín-Belmonte F, Kremer L, Albar JP, Correas I, Vaerman JP, Marazuela M, Byrne JA, Alonso MA., Free PMC Article | 01/21/2010 |