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    Snai1 snail family transcriptional repressor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 116490, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Metastasis-associated protein 1 promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis by up-regulating Snail expression.

    Metastasis-associated protein 1 promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis by up-regulating Snail expression.
    Qian W, Cai X, Qian Q, Zhang W, Tian L., Free PMC Article

    05/1/2021
    Changes in snail and SRF expression in the kidneys of diabetic rats during ageing.

    Changes in snail and SRF expression in the kidneys of diabetic rats during ageing.
    Kostic S, Williams B, Ksouri S, Hardung L, Filipovic N, Hamzic LF, Puljak L, Ghahramani N, Vukojevic K.

    09/26/2020
    The NRG1modified bone marrow mesenchymal stem cells (BMSCs) promoted the functional recovery of spinal cord injury (SCI). These results suggested that NRG1 significantly promoted the expression of MMP2 by upregulating the expression of Snail, and enhanced cell migration of the BMSCs conducive to the functional recovery of SCI

    Neuregulin‑1 impacting bone marrow mesenchymal stem cell migration is conducive to functional recovery following spinal cord injury.
    Yi XM, Chen Y, Tu GJ., Free PMC Article

    01/4/2020
    HIF-1A regulates epithelial-mesenchymal transition via the Snail and beta-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis.

    HIF-1α regulates EMT via the Snail and β-catenin pathways in paraquat poisoning-induced early pulmonary fibrosis.
    Zhu Y, Tan J, Xie H, Wang J, Meng X, Wang R., Free PMC Article

    01/14/2017
    Suggest that miR-30a target snail 1 protein may be related to atrial fibrillation-induced myocardial fibrosis.

    MiR-30a regulates the atrial fibrillation-induced myocardial fibrosis by targeting snail 1.
    Yuan CT, Li XX, Cheng QJ, Wang YH, Wang JH, Liu CL., Free PMC Article

    11/12/2016
    Transcription factor snail regulates tumor necrosis factor alpha-mediated synovial fibroblast activation in the rheumatoid joint.

    Transcription factor snail regulates tumor necrosis factor α-mediated synovial fibroblast activation in the rheumatoid joint.
    Chen SY, Shiau AL, Li YT, Lin CC, Jou IM, Liu MF, Wu CL, Wang CR.

    04/4/2015
    Caffeine inhibits the transcriptional factor Snail-1, down-regulating profibrogenic genes, and activates Nrf2 inducing antioxidant enzymes system, preventing inflammation and fibrosis.

    Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine.
    Gordillo-Bastidas D, Oceguera-Contreras E, Salazar-Montes A, González-Cuevas J, Hernández-Ortega LD, Armendáriz-Borunda J., Free PMC Article

    06/28/2014
    miR-30a negatively regulates Snai1-mediated EMT during peritoneal fibrosis in vitro and in vivo.

    miR-30a negatively regulates TGF-β1-induced epithelial-mesenchymal transition and peritoneal fibrosis by targeting Snai1.
    Zhou Q, Yang M, Lan H, Yu X.

    03/15/2014
    Angiotensin II plays a role in glomerular injury in experimental and human diabetic nephropathy via persistent activation of Notch1 and Snail signaling in podocytes resulting in down-regulation of nephrin expression.

    Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway.
    Gagliardini E, Perico N, Rizzo P, Buelli S, Longaretti L, Perico L, Tomasoni S, Zoja C, Macconi D, Morigi M, Remuzzi G, Benigni A., Free PMC Article

    10/26/2013
    these in vitro and in vivo data identify snail as a critical mediator for rBMMSC invasion induced by PDGF-BB.

    Snail mediates PDGF-BB-induced invasion of rat bone marrow mesenchymal stem cells in 3D collagen and chick chorioallantoic membrane.
    Lu C, Sun X, Sun L, Sun J, Lu Y, Yu X, Zhou L, Gao X.

    09/7/2013
    Data show that Snail1 confers resistance to TGF-beta-induced cell death and that it is sufficient to induce EMT in adult hepatocytes, cells otherwise refractory to this transition upon exposure to TGF-beta.

    Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes.
    Franco DL, Mainez J, Vega S, Sancho P, Murillo MM, de Frutos CA, Del Castillo G, López-Blau C, Fabregat I, Nieto MA.

    01/29/2011
    Snail1 is involved in renal tubular EMT and TGF-beta1 regulates Snail1 at the transcription and protein degradation levels

    Snail1 is involved in the renal epithelial-mesenchymal transition.
    Yoshino J, Monkawa T, Tsuji M, Inukai M, Itoh H, Hayashi M.

    01/21/2010
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