| Emerging role of an immunomodulatory protein secretoglobin 3A2 in human diseases. | Emerging role of an immunomodulatory protein secretoglobin 3A2 in human diseases.
Kimura S, Yokoyama S, Pilon AL, Kurotani R., Free PMC Article | 07/23/2022 |
| UGRP1 may be a novel marker in thyrocytes to predict Grave's disease patients who develop hypothyroidism. | Uterus globulin associated protein 1 (UGRP1) is a potential marker of progression of Graves' disease into hypothyroidism.
Zhou Z, Zuo CL, Li XS, Ye XP, Zhang QY, Wang P, Zhang RX, Chen G, Yang JL, Chen Y, Ma QY, Song HD. | 05/30/2020 |
| rs151333009 SNP showed a monomorphic genotype. Two promoter SNPs (rs6882292, -659 G/A and rs1368408, -112 G/A) showed significant association with asthma. These results suggest that the promoter SNPs (rs6882292 and rs1368408) of SCGB3A2 gene may contribute to susceptibility to asthma in a Korean population. | Association Between Secretoglobin Family 3A Member 2 (SCGB3A2) Gene Polymorphisms and Asthma in a Korean Population.
Kim SK, Seok H, Park HJ, Han K, Kang SW, Ban JY, Jung HJ, Kim KI, Lee BJ, Kim J, Chung JH., Free PMC Article | 03/17/2018 |
| This meta-analysis suggests that SCGB3A2 polymorphism at positions -112G>A was associated with Graves' disease both in Chinese and Caucasian population. | The association of SCGB3A2 polymorphisms with the risk of Graves' disease: a meta-analysis.
Xue L, Han B, Pan C, Song H. | 01/31/2015 |
| the SCGB3A2 -112G >A polymorphism may be considered as a likely marker linking susceptibility to allergy/asthma and Graves' disease | The -112G>A polymorphism of the secretoglobin 3A2 (SCGB3A2) gene encoding uteroglobin-related protein 1 (UGRP1) increases risk for the development of Graves' disease in subsets of patients with elevated levels of immunoglobulin E.
Chistiakov DA, Voronova NV, Turakulov RI, Savost'anov KV. | 08/27/2011 |
| Reduced production of UGRP1, which is likely due, at least in part, to a local cytokine environment, may contribute to the hyper-inflammation in chronic rhinosinusitis and correlates with response to surgery. | The cytokine-driven regulation of secretoglobins in normal human upper airway and their expression, particularly that of uteroglobin-related protein 1, in chronic rhinosinusitis.
Lu X, Wang N, Long XB, You XJ, Cui YH, Liu Z., Free PMC Article | 07/2/2011 |
| This study documents the association between polymorphisms in UGRP1 and the common cold, suggesting a potential role in its pathogenesis. | Variation in Uteroglobin-Related Protein 1 (UGRP1) gene is associated with allergic rhinitis in Singapore Chinese.
Andiappan AK, Yeo WS, Parate PN, Anantharaman R, Suri BK, Wang de Y, Chew FT., Free PMC Article | 06/4/2011 |
| Results demonstrate that SCGB3A2 is a useful marker for diagnosis of pulmonary tumors both in mice and humans. | Secretoglobin 3A2/uteroglobin-related protein 1 is a novel marker for pulmonary carcinoma in mice and humans.
Kurotani R, Kumaki N, Naizhen X, Ward JM, Linnoila RI, Kimura S., Free PMC Article | 04/2/2011 |
| pattern of UGRP-1 concentration resembled that of Clara cell protein, both proteins occurring in high concentrations in amniotic fluid, sputum and BALF and in much lower concentrations in serum and urine | Development of a new sensitive ELISA for the determination of uteroglobin-related protein 1, a new potential biomarker.
Van De Velde V, Courtens W, Bernard A. | 02/26/2011 |
| association was detected between SCGB3A2 and U.K. Caucasian Graves' disease subjects but the size of effect was smaller than that seen in the Oriental population (odds ratio = 1.28-1.73). | Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.
Simmonds MJ, Yesmin K, Newby PR, Brand OJ, Franklyn JA, Gough SC, Simmonds MJ, Yesmin K, Newby PR, Brand OJ, Franklyn JA, Gough SC. | 06/28/2010 |
| SCGB3A2 gene may contribute to Graves' disease susceptibility. | Functional SNPs in the SCGB3A2 promoter are associated with susceptibility to Graves' disease.
Song HD, Liang J, Shi JY, Zhao SX, Liu Z, Zhao JJ, Peng YD, Gao GQ, Tao J, Pan CM, Shao L, Cheng F, Wang Y, Yuan GY, Xu C, Han B, Huang W, Chu X, Chen Y, Sheng Y, Li RY, Su Q, Gao L, Jia WP, Jin L, Chen MD, Chen SJ, Chen Z, Chen JL, Song HD, Liang J, Shi JY, Zhao SX, Liu Z, Zhao JJ, Peng YD, Gao GQ, Tao J, Pan CM, Shao L, Cheng F, Wang Y, Yuan GY, Xu C, Han B, Huang W, Chu X, Chen Y, Sheng Y, Li RY, Su Q, Gao L, Jia WP, Jin L, Chen MD, Chen SJ, Chen Z, Chen JL. | 01/21/2010 |
| plasma UGRP1 levels were associated with the G-112A UGRP1 gene promoter polymorphism and the severity of asthma | Plasma UGRP1 levels associate with promoter G-112A polymorphism and the severity of asthma.
Inoue K, Wang X, Saito J, Tanino Y, Ishida T, Iwaki D, Fujita T, Kimura S, Munakata M, Inoue K, Wang X, Saito J, Tanino Y, Ishida T, Iwaki D, Fujita T, Kimura S, Munakata M., Free PMC Articles: PMC2768603, PMC2768603 | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (6) articlesConfirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.
Simmonds MJ, Yesmin K, Newby PR, Brand OJ, Franklyn JA, Gough SC, Simmonds MJ, Yesmin K, Newby PR, Brand OJ, Franklyn JA, Gough SC. Analyses of associations with asthma in four asthma population samples from Canada and Australia.
Daley D, Lemire M, Akhabir L, Chan-Yeung M, He JQ, McDonald T, Sandford A, Stefanowicz D, Tripp B, Zamar D, Bosse Y, Ferretti V, Montpetit A, Tessier MC, Becker A, Kozyrskyj AL, Beilby J, McCaskie PA, Musk B, Warrington N, James A, Laprise C, Palmer LJ, Paré PD, Hudson TJ. Functional SNPs in the SCGB3A2 promoter are associated with susceptibility to Graves' disease.
Song HD, Liang J, Shi JY, Zhao SX, Liu Z, Zhao JJ, Peng YD, Gao GQ, Tao J, Pan CM, Shao L, Cheng F, Wang Y, Yuan GY, Xu C, Han B, Huang W, Chu X, Chen Y, Sheng Y, Li RY, Su Q, Gao L, Jia WP, Jin L, Chen MD, Chen SJ, Chen Z, Chen JL, Song HD, Liang J, Shi JY, Zhao SX, Liu Z, Zhao JJ, Peng YD, Gao GQ, Tao J, Pan CM, Shao L, Cheng F, Wang Y, Yuan GY, Xu C, Han B, Huang W, Chu X, Chen Y, Sheng Y, Li RY, Su Q, Gao L, Jia WP, Jin L, Chen MD, Chen SJ, Chen Z, Chen JL. Plasma UGRP1 levels associate with promoter G-112A polymorphism and the severity of asthma.
Inoue K, Wang X, Saito J, Tanino Y, Ishida T, Iwaki D, Fujita T, Kimura S, Munakata M, Inoue K, Wang X, Saito J, Tanino Y, Ishida T, Iwaki D, Fujita T, Kimura S, Munakata M. Association study between the IL4, IL13, IRF1 and UGRP1 genes in chromosomal 5q31 region and Chinese Graves' disease.
Yang Y, Lingling S, Ying J, Yushu L, Zhongyan S, Wei H, Weiping T. Uteroglobin-related protein 1(UGRP1) gene polymorphisms and atopic asthma in the Indian population.
Batra J, Niphadkar PV, Sharma SK, Ghosh B. | 03/13/2008 |
| results suggest that the -112G/A polymorphism does not play a significant role in the genetic predisposition of the UGRP1 gene in atopic asthma in the Sicilian population | Uteroglobin-related protein 1 gene -112G/a polymorphism and atopic asthma in Sicilian children.
Rigoli L, Di Bella C, Procopio V, Finocchiaro G, Amorini M, Lo Giudice G, Cuppari C, Salpietro CD. | 01/21/2010 |
| polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma | A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma.
Niimi T, Munakata M, Keck-Waggoner CL, Popescu NC, Levitt RC, Hisada M, Kimura S., Free PMC Article | 01/21/2010 |
| results demonstrate that interleukin-10 induces uteroglobin related protein 1(UGRP1) gene expression in lung epithelial cells through transcription factor T/EBP/NKX2.1-dependent pathway | Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1.
Srisodsai A, Kurotani R, Chiba Y, Sheikh F, Young HA, Donnelly RP, Kimura S. | 01/21/2010 |
| By in situ hybridization, UGRP1 is found to be expressed by lung Clara-like cells in the bronchial epithelium and up-regulated in lung epithelium of a patient with cystic fibrosis. | Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair.
Bin LH, Nielson LD, Liu X, Mason RJ, Shu HB. | 01/21/2010 |