| LINC00943 knockdown attenuates MPP(+)-induced neuronal damage via miR-15b-5p/RAB3IP axis in SK-N-SH cells. | LINC00943 knockdown attenuates MPP(+)-induced neuronal damage via miR-15b-5p/RAB3IP axis in SK-N-SH cells.
Meng C, Gao J, Ma Q, Sun Q, Qiao T. | 10/30/2021 |
| Long noncoding RNA NEAT1 knockdown inhibits MPP(+)-induced apoptosis, in fl ammation and cytotoxicity in SK-N-SH cells by regulating miR-212-5p/RAB3IP axis. | Long noncoding RNA NEAT1 knockdown inhibits MPP(+)-induced apoptosis, inflammation and cytotoxicity in SK-N-SH cells by regulating miR-212-5p/RAB3IP axis.
Liu R, Li F, Zhao W. | 05/22/2021 |
| Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling. | Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling.
Choi J, Sung JY, Lee S, Yoo J, Rongo C, Kim YN, Shim J., Free PMC Article | 03/6/2021 |
| C7orf43 directly binds to Rabin8 and that C7orf43 knockdown diminishes Rabin8 preciliary centrosome accumulation. | The C7orf43/TRAPPC14 component links the TRAPPII complex to Rabin8 for preciliary vesicle tethering at the mother centriole during ciliogenesis.
Cuenca A, Insinna C, Zhao H, John P, Weiss MA, Lu Q, Walia V, Specht S, Manivannan S, Stauffer J, Peden AA, Westlake CJ., Free PMC Article | 06/27/2020 |
| The crystal structure of tetrameric Rabin8, guanine nucleotide exchange factors (GEFs) domain reveals an occluded Rab8 binding site suggesting that this oligomer is enzymatically inactive, a notion that's verified experimentally using Rabin8/Rab8 GEF assays. | Crystal structure of tetrameric human Rabin8 GEF domain.
Vetter M, Boegholm N, Christensen A, Bhogaraju S, Andersen MB, Lorentzen A, Lorentzen E. | 02/9/2019 |
| role of Rab3IP in inducing an invasive phenotype in gastric cancer cells, in addition to its involvement in EMT. | Rab3IP interacts with SSX2 and enhances the invasiveness of gastric cancer cells.
Ren H, Xu Z, Guo W, Deng Z, Yu X. | 01/19/2019 |
| Authors show that Rab11-GMPPNP-FIP3-Rabin8 is more stable than Rab11-GMPPNP-Rabin8, owing to direct interaction between Rabin8 and FIP3 within the dual effector-bound complex. | Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11.
Vetter M, Stehle R, Basquin C, Lorentzen E. | 05/7/2016 |
| the role of Rabin8 (a mammalian ortholog of Sec2p) with Rab8-nucleotide-exchange factor activity in autophagy in mammalian cells, was examined. | Rabin8 suppresses autophagosome formation independently of its guanine nucleotide-exchange activity towards Rab8.
Amagai Y, Itoh T, Fukuda M, Mizuno K. | 04/30/2016 |
| Rab11-FIP3 coordinates the interactions of ASAP1 and Rab11a with Rabin8. | The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting.
Wang J, Deretic D., Free PMC Article | 04/23/2016 |
| Rabin8 was identified as a direct phospho-substrate of ERK1/2 in response to EGF signaling. | Activation of Rab8 guanine nucleotide exchange factor Rabin8 by ERK1/2 in response to EGF signaling.
Wang J, Ren J, Wu B, Feng S, Cai G, Tuluc F, Peränen J, Guo W., Free PMC Article | 04/25/2015 |
| RABIN3 interacts with the cancer-related protein SSX2 and a novel nuclear protein, SSX2IP. | The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
de Bruijn DR, dos Santos NR, Kater-Baats E, Thijssen J, van den Berk L, Stap J, Balemans M, Schepens M, Merkx G, van Kessel AG. | 01/21/2010 |