| Mitochondrial uncoupling protein 2 is regulated through heterogeneous nuclear ribonucleoprotein K in lead exposure models. | Mitochondrial uncoupling protein 2 is regulated through heterogeneous nuclear ribonucleoprotein K in lead exposure models.
Zhu G, Zhu Q, Zhang W, Hui C, Li Y, Yang M, Pang S, Li Y, Xue G, Chen H. | 09/25/2021 |
| results showed that hnRNP K was widely distributed in gonocytes, spermatogonia, sertoli cells and Leydig cells. The dynamic expression profile of hnRNP K may imply its crucial and potential roles in the development of the testis. | Expression analysis of multifunctional RNA-binding protein hnRNP K during development of mammalian testis.
Xu H, Zhang P, Li R, Wu W, Wang S, Xu Y. | 02/16/2019 |
| Results show that synaptic activity and BDNF regulate hnRNP K and hnRNP K-bound mRNAs in vitro and in vivo. The large number of transcripts showing a decreased coimmunoprecipitation with hnRNP K on stimulation with BDNF suggests a role for this RNP in the regulation of neuronal function in general and, in particular, in the BDNF-mediated plasticity events. | The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons.
Leal G, Comprido D, de Luca P, Morais E, Rodrigues L, Mele M, Santos AR, Costa RO, Pinto MJ, Patil S, Berentsen B, Afonso P, Carreto L, Li KW, Pinheiro P, Almeida RD, Santos MAS, Bramham CR, Duarte CB., Free PMC Article | 08/11/2018 |
| hnRNP K regulates dendritic spine density and long-term potentiation in cultured hippocampal neurons from embryonic rats. hnRNP K knockdown prevents ERK cascade activation. | Loss of hnRNP K impairs synaptic plasticity in hippocampal neurons.
Folci A, Mapelli L, Sassone J, Prestori F, D'Angelo E, Bassani S, Passafaro M., Free PMC Article | 08/30/2014 |
| hnRNP-K is required for myelin basic protein synthesis. | Translation of myelin basic protein mRNA in oligodendrocytes is regulated by integrin activation and hnRNP-K.
Laursen LS, Chan CW, Ffrench-Constant C., Free PMC Article | 07/9/2011 |
| These results suggest that transcription factor Hnrnpk is a key regulator for primordial follicle assembly and development, which provides a new potential therapeutic target to regulate ovarian function and treat ovarian disease. | Hnrnpk, a protein differentially expressed in immature rat ovarian development, is required for normal primordial follicle assembly and development.
Wang N, Zhang P, Guo X, Zhou Z, Sha J. | 04/30/2011 |
| Decreased recruitment of hnRNP K protein to the mutated sequence causes the low expression of CYP2D2 mRNA in dark agouti rats. | The importance of heterogeneous nuclear ribonucleoprotein K on cytochrome P450 2D2 gene regulation: its binding is reduced in Dark Agouti rats.
Sakai N, Sakamoto KQ, Fujita S, Ishizuka M. | 01/21/2010 |
| hnRNP K is a nuclear protein that binds to the insulin-responsive element of the rat angiotensinogen gene promoter and modulates angiotensinogen gene transcription in the kidney | Heterogeneous nuclear ribonucleoprotein K modulates angiotensinogen gene expression in kidney cells.
Wei CC, Zhang SL, Chen YW, Guo DF, Ingelfinger JR, Bomsztyk K, Chan JS. | 01/21/2010 |
| In vitro a single kinase can phosphorylate K protein on multiple sites spanning the entire length of the protein, including residues contained within the RNA/DNA-binding domains. | Casein kinases phosphorylate multiple residues spanning the entire hnRNP K length.
Mikula M, Karczmarski J, Dzwonek A, Rubel T, Hennig E, Dadlez M, Bujnicki JM, Bomsztyk K, Ostrowski J. | 01/21/2010 |
| analysis of the hnRNP K protein-protein interactome | Landscape of the hnRNP K protein-protein interactome.
Mikula M, Dzwonek A, Karczmarski J, Rubel T, Dadlez M, Wyrwicz LS, Bomsztyk K, Ostrowski J. | 01/21/2010 |
| In the central nervous system, hnRNP K mRNA expression gradually decreases during development until it is restricted to a very limited number of structures including most notably the hippocampus and the retina. | Cell-type-specific and developmental regulation of heterogeneous nuclear ribonucleoprotein K mRNA in the rat nervous system.
Blanchette AR, Fuentes Medel YF, Gardner PD. | 01/21/2010 |
| satellite I RNA binds to hnRNP K protein | Mitochondria-associated satellite I RNA binds to hnRNP K protein.
Klimek-Tomczak K, Mikula M, Dzwonek A, Paziewska A, Wyrwicz LS, Hennig EE, Ostrowski J. | 01/21/2010 |