| TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5. | TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Wu M, Jin Q, Xu X, Fan J, Chen W, Miao M, Gu R, Zhang S, Guo Y, Huang S, Zhang Y, Zhang A, Jia Z., Free PMC Article | 09/7/2023 |
| Survivin is essential for thermogenic program and metabolic homeostasis in mice. | Survivin is essential for thermogenic program and metabolic homeostasis in mice.
Alimujiang M, Sun J, Chen S, Bai N, Chen S, Hu F, Ma J, Xu Y, Xu J, Ma X, Yang Y., Free PMC Article | 05/7/2022 |
| Ablation of Survivin in T Cells Attenuates Acute Allograft Rejection after Murine Heterotopic Heart Transplantation by Inducing Apoptosis. | Ablation of Survivin in T Cells Attenuates Acute Allograft Rejection after Murine Heterotopic Heart Transplantation by Inducing Apoptosis.
Xu H, Yu J, Cui J, Chen Z, Zhang X, Zou Y, Du Y, Li Y, Le S, Jiang L, Xia J, Wu J., Free PMC Article | 12/25/2021 |
| Survivin-positive circulating tumor cells as a marker for metastasis of hepatocellular carcinoma. | Survivin-positive circulating tumor cells as a marker for metastasis of hepatocellular carcinoma.
Yu J, Wang Z, Zhang H, Wang Y, Li DQ., Free PMC Article | 12/18/2021 |
| Survivin expression is essential for early activation of hepatic stellate cells and fibrosis progression in chronic liver injury. | Survivin expression is essential for early activation of hepatic stellate cells and fibrosis progression in chronic liver injury.
Sharma S, Ghufran SM, Das B, Roy B, Ghose S, Biswas S. | 12/18/2021 |
| Inhibition of survivin induces spindle disorganization, chromosome misalignment, and DNA damage during mouse embryo development. | Inhibition of survivin induces spindle disorganization, chromosome misalignment, and DNA damage during mouse embryo development.
Pan MH, Ju JQ, Li XH, Xu Y, Wang JD, Ren YP, Lu X, Sun SC., Free PMC Article | 09/4/2021 |
| BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. | BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells.
Lin TY, Chan HH, Chen SH, Sarvagalla S, Chen PS, Coumar MS, Cheng SM, Chang YC, Lin CH, Leung E, Cheung CHA., Free PMC Article | 07/31/2021 |
| Does survivin overexpression enhance the efficiency of fibroblast cell-based wound therapy? | Does survivin overexpression enhance the efficiency of fibroblast cell-based wound therapy?
Shojaei-Ghahrizjani F, Rahmati S, Mirzaei SA, Banitalebi-Dehkordi M. | 06/26/2021 |
| BIRC5 Expression is Regulated in Uterine Epithelium During the Estrous Cycle. | BIRC5 Expression is Regulated in Uterine Epithelium During the Estrous Cycle.
Cho M, Lee OH, Chang EM, Lee S, Moon S, Lee J, Park H, Park KH, Park C, Hong K, Choi Y., Free PMC Article | 01/23/2021 |
| The protection effects of survivin in the cell model of CVB3-induced viral myocarditis. | The protection effects of survivin in the cell model of CVB3-induced viral myocarditis.
Wu R, Wu T, Li P, Wang Q, Shi Y, Zhan Y, Zhang S, Xia T, Wang Z, Lv H. | 12/12/2020 |
| epithelial cell-produced survivin induced defects in apoptosis in eosinophils to contribute to eosinophilia in the intestine | Survivin induces defects in apoptosis in eosinophils in intestine with food allergy.
Gao H, Feng BS, Liu JQ, Mo LH, Geng XR, Xiao Y, Zhang YY, Hong JY, Liu ZJ, Liu ZG, Feng Y, Yang PC., Free PMC Article | 02/22/2020 |
| The existence of Pcdh7-BIRC5 signaling cascade in the cortical neurons and represent a potential therapeutic area for further investigation. | Overexpression of protocadherin 7 inhibits neuronal survival by downregulating BIRC5 in vitro.
Xiao H, Sun Z, Wan J, Hou S, Xiong Y. | 02/2/2019 |
| While induced by exposure to reactive oxygen species generating stresses, the ultimate expression of changes in radiation response is dependent upon the bi-functionality of the tumor associated protein survivin and its intracellular translocation. | Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity.
Miller RC, Murley JS, Rademaker AW, Woloschak GE, Li JJ, Weichselbaum RR, Grdina DJ., Free PMC Article | 12/30/2017 |
| HDL-associated sphingosine 1-phosphate inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression. | High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression.
Feuerborn R, Becker S, Potì F, Nagel P, Brodde M, Schmidt H, Christoffersen C, Ceglarek U, Burkhardt R, Nofer JR. | 11/4/2017 |
| Survivin also attenuates DNA damage related to PARP activation and inhibits TNFalpha-induced lipolysis, suggesting that Survivin may facilitate adipocyte maintenance in response to inflammatory stimuli. | Enhanced expression of Survivin has distinct roles in adipocyte homeostasis.
Ju L, Zhang X, Deng Y, Han J, Yang J, Chen S, Fang Q, Yang Y, Jia W., Free PMC Article | 10/28/2017 |
| The study assigns a new meiotic function to Cullin9 and reveals that it prevents mouse eggs from aneuploidy by regulating microtubule dynamics via survivin. | Cullin9 protects mouse eggs from aneuploidy by controlling microtubule dynamics via Survivin.
Dai X, Zhang M, Lu Y, Miao Y, Zhou C, Xiong B. | 10/7/2017 |
| this study shows that that sorafenib promotes the survival of bone marrow cells by up-regulating survivin | Small-molecule inhibitor sorafenib regulates immunoreactions by inducing survival and differentiation of bone marrow cells.
Zhao X, Cao M, Lu Z, Wang T, Ren Y, Liu C, Nelson D. | 07/1/2017 |
| Survivin was regulated by TGF-beta and was found to be highly expressed during mucosal healing following intestinal inflammation | Survivin is a guardian of the intestinal stem cell niche and its expression is regulated by TGF-β.
Martini E, Schneider E, Neufert C, Neurath MF, Becker C., Free PMC Article | 06/24/2017 |
| SurvivinT34A combined with arsenic trioxide induces a loss of mitochondria membrane potential | SurvivinT34A increases the therapeutic efficacy of arsenic trioxide in mouse hepatocellular carcinoma models.
Huang A, Yue D, Liao D, Cheng L, Ma J, Wei Y, Tong A, Cheng P. | 03/25/2017 |
| Survivin is a key regulator of gut tissue integrity by regulating epithelial homeostasis in the stem cell niche. | Loss of Survivin in Intestinal Epithelial Progenitor Cells Leads to Mitotic Catastrophe and Breakdown of Gut Immune Homeostasis.
Martini E, Wittkopf N, Günther C, Leppkes M, Okada H, Watson AJ, Podstawa E, Backert I, Amann K, Neurath MF, Becker C. | 11/5/2016 |
| TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt in CPCs to mediate cardioprotection and improve cardiac function. | Cardioprotective Actions of TGFβRI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors.
Ho YS, Tsai WH, Lin FC, Huang WP, Lin LC, Wu SM, Liu YR, Chen WP. | 11/5/2016 |
| Survivin is a key gene for regulating squamous cell carcinoma (SCC) cancer stem cell formation and cancer SCC development. | Survivin Modulates Squamous Cell Carcinoma-Derived Stem-Like Cell Proliferation, Viability and Tumor Formation in Vivo.
Lotti R, Palazzo E, Petrachi T, Dallaglio K, Saltari A, Truzzi F, Quadri M, Puviani M, Maiorana A, Marconi A, Pincelli C., Free PMC Article | 10/22/2016 |
| In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 and ki67. | Effect of survivin on tumor growth of colorectal cancer in vivo.
Cai Y, Ma W, Huang X, Cao L, Li H, Jiang Y, Lu N, Yin Y., Free PMC Article | 10/22/2016 |
| survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation. | Essential Role for Survivin in the Proliferative Expansion of Progenitor and Mature B Cells.
Miletic AV, Jellusova J, Cato MH, Lee CR, Baracho GV, Conway EM, Rickert RC., Free PMC Article | 07/2/2016 |
| Survivin directly participates in PRL-mediated beta cell proliferation via Akt, STAT5-PIM and ERK signalling pathways during pregnancy | Prolactin-stimulated survivin induction is required for beta cell mass expansion during pregnancy in mice.
Xu Y, Wang X, Gao L, Zhu J, Zhang H, Shi H, Woo M, Wu X. | 06/11/2016 |