| Verification of the gene and protein expression of the aquaglyceroporin AQP3 in the mammalian lens. | Verification of the gene and protein expression of the aquaglyceroporin AQP3 in the mammalian lens.
Petrova RS, Francis N, Schey KL, Donaldson PJ. | 03/11/2024 |
| Targeting Aquaporin-3 Attenuates Skin Inflammation in Rosacea. | Targeting Aquaporin-3 Attenuates Skin Inflammation in Rosacea.
Chen M, Peng Q, Tan Z, Xu S, Wang Y, Wu A, Xiao W, Wang Q, Xie H, Li J, Shi W, Deng Z., Free PMC Article | 11/21/2023 |
| AQP3-mediated activation of the AMPK/SIRT1 signaling pathway curtails gallstone formation in mice by inhibiting inflammatory injury of gallbladder mucosal epithelial cells. | AQP3-mediated activation of the AMPK/SIRT1 signaling pathway curtails gallstone formation in mice by inhibiting inflammatory injury of gallbladder mucosal epithelial cells.
Wang G, Zhang H, Zhou Z, Jin W, Zhang X, Ma Z, Wang X., Free PMC Article | 08/31/2023 |
| Advanced Glycation End Products and Activation of Toll-like Receptor-2 and -4 Induced Changes in Aquaporin-3 Expression in Mouse Keratinocytes. | Advanced Glycation End Products and Activation of Toll-like Receptor-2 and -4 Induced Changes in Aquaporin-3 Expression in Mouse Keratinocytes.
Luo Y, Uaratanawong R, Choudhary V, Hardin M, Zhang C, Melnyk S, Chen X, Bollag WB., Free PMC Article | 01/28/2023 |
| Characteristics of aquaporin 1, 3, and 5 expression during early murine salivary gland development. | Characteristics of aquaporin 1, 3, and 5 expression during early murine salivary gland development.
de Paula F, Tucker AS, Teshima THN, de Souza MM, Coutinho-Camillo CM, Nico MMS, Lourenço SV., Free PMC Article | 08/14/2021 |
| Distinct expression patterns of aquaporin 3 and 5 in ductal and alveolar epithelial cells in mouse mammary glands before and after parturition. | Distinct expression patterns of aquaporin 3 and 5 in ductal and alveolar epithelial cells in mouse mammary glands before and after parturition.
Kaihoko Y, Tsugami Y, Suzuki N, Suzuki T, Nishimura T, Kobayashi K. | 02/2/2021 |
| Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation. | Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation.
Nalle SC, Barreira da Silva R, Zhang H, Decker M, Chalouni C, Xu M, Posthuma G, de Mazière A, Klumperman J, Baz Morelli A, Fleire SJ, Verkman AS, Trombetta ES, Albert ML, Mellman I., Free PMC Article | 12/19/2020 |
| Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury. | Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury.
Hara-Chikuma M, Tanaka M, Verkman AS, Yasui M., Free PMC Article | 11/21/2020 |
| AQP3 deletion slows cyst enlargement Pkd1 model of autosomal dominant polycystic kidney disease. | Aquaporin-3 deficiency slows cyst enlargement in experimental mouse models of autosomal dominant polycystic kidney disease.
Wang W, Geng X, Lei L, Jia Y, Li Y, Zhou H, Verkman AS, Yang B., Free PMC Article | 05/23/2020 |
| The expression levels of AQP3 and occludin were downregulated after septic intestinal injury, while treatment with glycerol, which acts as a substitute for AQP3, partly ameliorated intestinal injury and improved the survival rate. This preliminary experiment suggests that AQP3 may protect the intestinal tract against the effects of sepsis. | Role of Aquaporin-3 in Intestinal Injury Induced by Sepsis.
Zhu Y, Wang Y, Teng W, Shan Y, Yi S, Zhu S, Li Y. | 02/22/2020 |
| Glycolic acid attenuates UVB-induced aquaporin-3, matrix metalloproteinase-9 expression, and collagen degradation in keratinocytes and mouse skin. | Glycolic acid attenuates UVB-induced aquaporin-3, matrix metalloproteinase-9 expression, and collagen degradation in keratinocytes and mouse skin.
Tang SC, Tang LC, Liu CH, Liao PY, Lai JC, Yang JH. | 02/15/2020 |
| The results of this study suggest that skin AQP3 expression decreases in diabetes, which may limit water transport from the vessel side to the corneum side, causing dry skin. | Study of the Mechanism Underlying the Onset of Diabetic Xeroderma Focusing on an Aquaporin-3 in a Streptozotocin-Induced Diabetic Mouse Model.
Ikarashi N, Mizukami N, Kon R, Kaneko M, Uchino R, Fujisawa I, Fukuda N, Sakai H, Kamei J., Free PMC Article | 01/11/2020 |
| This study may provide new insights into therapeutic approaches for schizophrenia by regulating AQP3 expression, which is associated with paranodal disruption | Dysregulation of schizophrenia-related aquaporin 3 through disruption of paranode influences neuronal viability.
Kunisawa K, Shimizu T, Kushima I, Aleksic B, Mori D, Osanai Y, Kobayashi K, Taylor AM, Bhat MA, Hayashi A, Baba H, Ozaki N, Ikenaka K., Free PMC Article | 09/28/2019 |
| increased expression with hyperosmolarity associated with notochordal cell to small nucleus pulposus cell differentiation | Hyperosmolarity induces notochordal cell differentiation with aquaporin3 upregulation and reduced N-cadherin expression.
Palacio-Mancheno PE, Evashwick-Rogler TW, Laudier DM, Purmessur D, Iatridis JC., Free PMC Article | 03/23/2019 |
| results support a novel role for AQP3 in modulating renal injury and suggest the mechanisms involved in protection against hypoxic injury. | Aquaporin-3 deletion in mice results in renal collecting duct abnormalities and worsens ischemia-reperfusion injury.
Lei L, Wang W, Jia Y, Su L, Zhou H, Verkman AS, Yang B. | 12/1/2018 |
| The results of this study suggest that NAR relieves Lop-induced constipation by increasing the levels of interstitial cells of Cajal markers (c-Kit and SCF), as well as AQP3. Thus, NAR may be effective as a candidate in patients suffering from lifestyle-induced constipation. | Naringenin induces laxative effects by upregulating the expression levels of c-Kit and SCF, as well as those of aquaporin 3 in mice with loperamide-induced constipation.
Yin J, Liang Y, Wang D, Yan Z, Yin H, Wu D, Su Q., Free PMC Article | 07/28/2018 |
| Increased expression of AQP3 and AQP10 in murine skin with the concomitant presence of an inflammatory stimulus (IMQ) and contact with detergent-containing water increases skin acanthosis and affects the biology of keratinocytes. | Overexpression of AQP3 and AQP10 in the skin exacerbates psoriasiform acanthosis.
Soler DC, Young AE, Griffith AD, Fu PF, Cooper KD, McCormick TS, Popkin DL., Free PMC Article | 07/21/2018 |
| AQP3(-/-) mice showed impaired healing of superficial wounds in the colon and impaired mucosal innate immune responses against Citrobacter rodentium infection. | Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia.
Thiagarajah JR, Chang J, Goettel JA, Verkman AS, Lencer WI., Free PMC Article | 04/21/2018 |
| These results imply a critical role of AQP3 in asthma. | Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma.
Ikezoe K, Oga T, Honda T, Hara-Chikuma M, Ma X, Tsuruyama T, Uno K, Fuchikami J, Tanizawa K, Handa T, Taguchi Y, Verkman AS, Narumiya S, Mishima M, Chin K., Free PMC Article | 03/31/2018 |
| This study found that both the airway epithelial cells of AQP3-knockout mice and AQP3-knockdown HBECs exhibited an obviously impaired self-healing capacity with defective epithelial cell migration through AQP3-facilitated glycerol transport. | Impaired self-healing capacity in airway epithelia lacking aquaporin-3.
Zhu HX, Zhou JB, Zhu XD, Zhou J, Li J, Song YL, Bai CX. | 09/23/2017 |
| Decreased glycerol efflux from the skeletal muscles in AQP3 knockout mice may result in low exercise capacity. | The effect of AQP3 deficiency on fuel selection during a single bout of exhausting exercise.
Lim JH, Kim DH, Han DW, Kwak JY, Bae HR. | 08/26/2017 |
| treatment of human HepG2 cells with TCDD also increased the expression of AQP3 mRNA and protein | Regulation of Aquaporin 3 Expression by the AhR Pathway Is Critical to Cell Migration.
Bui LC, Tomkiewicz C, Pierre S, Chevallier A, Barouki R, Coumoul X. | 11/5/2016 |
| AQP3-facilitated H2O2 transport is required for NF-kappaB activation in keratinocytes in the development of psoriasis. | Aquaporin-3-mediated hydrogen peroxide transport is required for NF-κB signalling in keratinocytes and development of psoriasis.
Hara-Chikuma M, Satooka H, Watanabe S, Honda T, Miyachi Y, Watanabe T, Verkman AS., Free PMC Article | 04/9/2016 |
| Studied the effect of the total tannins extract of rhubarb on expression od aquaporin 2 and auqaporin 3 in diarrhoea mice. | Rhubarb tannins extract inhibits the expression of aquaporins 2 and 3 in magnesium sulphate-induced diarrhoea model.
Liu C, Zheng Y, Xu W, Wang H, Lin N., Free PMC Article | 04/18/2015 |
| AQP3 has a pro-differentiative role in epidermal keratinocytes and PLD2 activity is necessary for this effect. | Aquaporin-3 re-expression induces differentiation in a phospholipase D2-dependent manner in aquaporin-3-knockout mouse keratinocytes.
Choudhary V, Olala LO, Qin H, Helwa I, Pan ZQ, Tsai YY, Frohman MA, Kaddour-Djebbar I, Bollag WB., Free PMC Article | 03/28/2015 |