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    Aqp4 aquaporin 4 [ Mus musculus (house mouse) ]

    Gene ID: 11829, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Neuroprotective Role of AQP4 Knockdown in Astrocytes After Oxygen-Glucose Deprivation.

    Neuroprotective Role of AQP4 Knockdown in Astrocytes After Oxygen-Glucose Deprivation.
    Xing X, Zhang S., Free PMC Article

    10/25/2024
    Crucial role of Aquaporin-4 extended isoform in brain water Homeostasis and Amyloid-beta clearance: implications for Edema and neurodegenerative diseases.

    Crucial role of Aquaporin-4 extended isoform in brain water Homeostasis and Amyloid-β clearance: implications for Edema and neurodegenerative diseases.
    Abbrescia P, Signorile G, Valente O, Palazzo C, Cibelli A, Nicchia GP, Frigeri A., Free PMC Article

    10/10/2024
    Absence of Aquaporin-4 (AQP4) Prolongs the Presence of a CD11c+ Microglial Population during Postnatal Corpus Callosum Development.

    Absence of Aquaporin-4 (AQP4) Prolongs the Presence of a CD11c+ Microglial Population during Postnatal Corpus Callosum Development.
    Mayo F, González-Vinceiro L, Hiraldo-González L, Calle-Castillejo C, Torres-Rubio I, Mayo M, Ramírez-Lorca R, Echevarría M., Free PMC Article

    09/19/2024
    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia.

    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia.
    Yang J, Cao C, Liu J, Liu Y, Lu J, Yu H, Li X, Wu J, Yu Z, Li H, Chen G.

    09/5/2024
    The Role of Aquaporin 4 in Lacrimal Gland Ductal Fluid Secretion in Mice.

    The Role of Aquaporin 4 in Lacrimal Gland Ductal Fluid Secretion in Mice.
    Elekes G, Csapó V, Szarka D, Szalay L, Korsós MM, Tálosi D, Török D, Tóth-Molnár E., Free PMC Article

    08/30/2024
    Impact of aquaporin-4 and CD11c + microglia in the development of ependymal cells in the aqueduct: inferences to hydrocephalus.

    Impact of aquaporin-4 and CD11c + microglia in the development of ependymal cells in the aqueduct: inferences to hydrocephalus.
    Mayo F, González-Vinceiro L, Hiraldo-González L, Rodríguez-Gómez FD, Calle-Castillejo C, Mayo M, Netti V, Ramírez-Lorca R, Echevarría M., Free PMC Article

    07/25/2024
    Aquaporin-4 deletion leads to reduced infarct volume and increased peri-infarct astrocyte reactivity in a mouse model of cortical stroke.

    Aquaporin-4 deletion leads to reduced infarct volume and increased peri-infarct astrocyte reactivity in a mouse model of cortical stroke.
    Skauli N, Zohoorian N, Banitalebi S, Geiseler S, Salameh M, Rao SB, Morland C, Ottersen OP, Amiry-Moghaddam M.

    07/11/2024
    The effect of aquaporin-4 inhibition on cerebrospinal fluid-tissue water exchange in mouse brain detected by magnetization transfer indirect spin labeling MRI.

    The effect of aquaporin-4 inhibition on cerebrospinal fluid-tissue water exchange in mouse brain detected by magnetization transfer indirect spin labeling MRI.
    Chen Z, Lai JHC, Xu J, Zhang H, Huang J, Chan KWY.

    06/20/2024
    AQP4 regulates ferroptosis and oxidative stress of Muller cells in diabetic retinopathy by regulating TRPV4.

    AQP4 regulates ferroptosis and oxidative stress of Muller cells in diabetic retinopathy by regulating TRPV4.
    Chen Z, Liu B, Zhou D, Lei M, Yang J, Hu Z, Duan W.

    06/13/2024
    Macroscopic changes in aquaporin-4 underlie blast traumatic brain injury-related impairment in glymphatic function.

    Macroscopic changes in aquaporin-4 underlie blast traumatic brain injury-related impairment in glymphatic function.
    Braun M, Sevao M, Keil SA, Gino E, Wang MX, Lee J, Haveliwala MA, Klein E, Agarwal S, Pedersen T, Rhodes CH, Jansson D, Cook D, Peskind E, Perl DP, Piantino J, Schindler AG, Iliff JJ., Free PMC Article

    06/11/2024
    NHH promotes Sepsis-associated Encephalopathy with the expression of AQP4 in astrocytes through the gut-brain Axis.

    NHH promotes Sepsis-associated Encephalopathy with the expression of AQP4 in astrocytes through the gut-brain Axis.
    Zhao L, Zhang Z, Wang P, Zhang N, Shen H, Wu H, Wei Z, Yang F, Wang Y, Yu Z, Li H, Hu Z, Zhai H, Wang Z, Su F, Xie K, Li Y., Free PMC Article

    06/3/2024
    Role of aquaporin-4 polarization in extracellular solute clearance.

    Role of aquaporin-4 polarization in extracellular solute clearance.
    Bojarskaite L, Nafari S, Ravnanger AK, Frey MM, Skauli N, Åbjørsbråten KS, Roth LC, Amiry-Moghaddam M, Nagelhus EA, Ottersen OP, Bogen IL, Thoren AE, Enger R., Free PMC Article

    03/29/2024
    B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.

    B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
    Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T., Free PMC Article

    03/23/2024
    Aquaporin-4 Deficiency is Associated with Cognitive Impairment and Alterations in astrocyte-neuron Lactate Shuttle.

    Aquaporin-4 Deficiency is Associated with Cognitive Impairment and Alterations in astrocyte-neuron Lactate Shuttle.
    Cha H, Choi JH, Jeon H, Kim JH, Kim M, Kim SJ, Park W, Lim JS, Lee E, Ahn JS, Kim JH, Hong SH, Park JE, Jung JH, Yoo HJ, Lee S.

    11/2/2023
    Deletion of aquaporin-4 improves capillary blood flow distribution in brain edema.

    Deletion of aquaporin-4 improves capillary blood flow distribution in brain edema.
    Bordoni L, Thoren AE, Gutiérrez-Jiménez E, Åbjørsbråten KS, Bjørnstad DM, Tang W, Stern M, Østergaard L, Nagelhus EA, Frische S, Ottersen OP, Enger R., Free PMC Article

    09/7/2023
    Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation.

    Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation.
    Xin W, Pan Y, Wei W, Tatenhorst L, Graf I, Popa-Wagner A, Gerner ST, Huber S, Kilic E, Hermann DM, Bähr M, Huttner HB, Doeppner TR., Free PMC Article

    08/10/2023
    GABA promotes interstitial fluid clearance in an AQP4-dependent manner by activating the GABAA R.

    GABA promotes interstitial fluid clearance in an AQP4-dependent manner by activating the GABA(A) R.
    Wu C, Zhang Q, Feng YW, Zhang N, Liu Q, Ou ZT, Lin T, Ding Q, Li G, Pei Z, Lan Y, Xu GQ.

    07/26/2023
    Connexin 43 Promotes Neurogenesis via Regulating Aquaporin-4 after Cerebral Ischemia.

    Connexin 43 Promotes Neurogenesis via Regulating Aquaporin-4 after Cerebral Ischemia.
    Chu H, Dong J, Tang Y, Huang C, Guo Q.

    07/26/2023
    T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity.

    T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity.
    Sagan SA, Moinfar Z, Moseley CE, Dandekar R, Spencer CM, Verkman AS, Ottersen OP, Sobel RA, Sidney J, Sette A, Anderson MS, Steinman L, Wilson MR, Sabatino JJ Jr, Zamvil SS., Free PMC Article

    07/24/2023
    High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization.

    High-intensity interval training ameliorates Alzheimer's disease-like pathology by regulating astrocyte phenotype-associated AQP4 polarization.
    Feng S, Wu C, Zou P, Deng Q, Chen Z, Li M, Zhu L, Li F, Liu TC, Duan R, Yang L., Free PMC Article

    06/28/2023
    Dystrophin Short Product, Dp71, Interacts with AQP4 and Kir4.1 Channels in the Mouse Cerebellar Glial Cells in Contrast to Dp427 at Inhibitory Postsynapses in the Purkinje Neurons.

    Dystrophin Short Product, Dp71, Interacts with AQP4 and Kir4.1 Channels in the Mouse Cerebellar Glial Cells in Contrast to Dp427 at Inhibitory Postsynapses in the Purkinje Neurons.
    Fujimoto T, Stam K, Yaoi T, Nakano K, Arai T, Okamura T, Itoh K.

    06/1/2023
    AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting Nav 1.6-Mediated Astrocyte Autophagy.

    AQP4 Aggravates Cognitive Impairment in Sepsis-Associated Encephalopathy through Inhibiting Na(v) 1.6-Mediated Astrocyte Autophagy.
    Zhu DD, Huang YL, Guo SY, Li N, Yang XW, Sui AR, Wu Q, Zhang Y, Kong Y, Li QF, Zhang T, Zheng WF, Li AP, Yu J, Ma TH, Li S., Free PMC Article

    05/20/2023
    The effect of aquaporin-4 mis-localization on Abeta deposition in mice.

    The effect of aquaporin-4 mis-localization on Aβ deposition in mice.
    Pedersen TJ, Keil SA, Han W, Wang MX, Iliff JJ.

    05/17/2023
    Aquaporin 4 is differentially increased and dislocated in association with tau and amyloid-beta.

    Aquaporin 4 is differentially increased and dislocated in association with tau and amyloid-beta.
    Kecheliev V, Boss L, Maheshwari U, Konietzko U, Keller A, Razansky D, Nitsch RM, Klohs J, Ni R.

    04/12/2023
    Prolonged Light Exposure Induces Circadian Impairment in Aquaporin-4-Knockout Mice.

    Prolonged Light Exposure Induces Circadian Impairment in Aquaporin-4-Knockout Mice.
    Murakami A, Tsuji K, Isoda M, Matsuo M, Abe Y, Yasui M, Okamura H, Tominaga K.

    03/31/2023
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