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    Bnip3 BCL2/adenovirus E1B interacting protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 12176, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    RNF31 alleviates liver steatosis by promoting p53/BNIP3-related mitophagy in hepatocytes.

    RNF31 alleviates liver steatosis by promoting p53/BNIP3-related mitophagy in hepatocytes.
    Chen Y, Yang F, Shi Y, Sheng J, Wang Y, Zhang L, Zhou J, Jin Y, Yan Y.

    07/3/2024
    Rbm46 inhibits reactive oxygen species in mouse embryonic stem cells through modulating BNIP3-mediated mitophagy.

    Rbm46 inhibits reactive oxygen species in mouse embryonic stem cells through modulating BNIP3-mediated mitophagy.
    Zhong J, Xu J, Chen X, Li N, Li S, Deng Z, Feng H, Ling X, Wang C, Zhou Z, Li L.

    04/12/2024
    The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress.

    The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress.
    Jeong DJ, Um JH, Kim YY, Shin DJ, Im S, Lee KM, Lee YH, Lim DS, Kim D, Yun J., Free PMC Article

    04/11/2024
    HIF-1 contributes to autophagy activation via BNIP3 to facilitate renal fibrosis in hypoxia in vitro and UUO in vivo.

    HIF-1 contributes to autophagy activation via BNIP3 to facilitate renal fibrosis in hypoxia in vitro and UUO in vivo.
    Liu J, Livingston MJ, Dong G, Wei Q, Zhang M, Mei S, Zhu J, Zhang C, Dong Z.,

    03/6/2024
    HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320.

    HDAC6 preserves BNIP3 expression and mitochondrial integrity by deacetylating p53 at lysine 320.
    Lee SI, Seo Y, Oanh HT, Vo TTH, Go H, Kim MH, Lee JY.

    01/4/2024
    Uncovering the Novel Role of NR1D1 in Regulating BNIP3-Mediated Mitophagy in Ulcerative Colitis.

    Uncovering the Novel Role of NR1D1 in Regulating BNIP3-Mediated Mitophagy in Ulcerative Colitis.
    Chen Y, Li J, Li S, Cheng Y, Fu X, Li J, Zhu L., Free PMC Article

    09/30/2023
    A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.

    A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.
    Cao Y, Zheng J, Wan H, Sun Y, Fu S, Liu S, He B, Cai G, Cao Y, Huang H, Li Q, Ma Y, Chen S, Wang F, Jiang H., Free PMC Article

    06/30/2023
    The interaction between adhesion protein 33 (TvAP33) and BNIP3 mediates the adhesion and pathogenicity of Trichomonas vaginalis to host cells.

    The interaction between adhesion protein 33 (TvAP33) and BNIP3 mediates the adhesion and pathogenicity of Trichomonas vaginalis to host cells.
    Zhang Z, Deng Y, Sheng W, Song X, Li Y, Li F, Pan Y, Tian X, Yang Z, Wang S, Wang M, Mei X., Free PMC Article

    06/23/2023
    The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral disc.

    The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral disc.
    Madhu V, Hernandez-Meadows M, Boneski PK, Qiu Y, Guntur AR, Kurland IJ, Barve RA, Risbud MV., Free PMC Article

    06/14/2023
    Contribution of HIF-1alpha/BNIP3-mediated autophagy to lipid accumulation during irinotecan-induced liver injury.

    Contribution of HIF-1α/BNIP3-mediated autophagy to lipid accumulation during irinotecan-induced liver injury.
    Shi C, Zhang Z, Xu R, Zhang Y, Wang Z., Free PMC Article

    04/26/2023
    Cobaltosic oxide-polyethylene glycol-triphenylphosphine nanoparticles ameliorate the acute-to-chronic kidney disease transition by inducing BNIP3-mediated mitophagy.

    Cobaltosic oxide-polyethylene glycol-triphenylphosphine nanoparticles ameliorate the acute-to-chronic kidney disease transition by inducing BNIP3-mediated mitophagy.
    Qin S, Liu C, Chen Y, Yao M, Liao S, Xin W, Gong S, Guan X, Li Y, Xiong J, Chen J, Shen Y, Liu Y, Zhao J, Huang Y.

    04/26/2023
    BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.

    BNIP3-mediated autophagy via the mTOR/ULK1 pathway induces primordial follicle loss after ovarian tissue transplantation.
    Liu F, Li M., Free PMC Article

    03/31/2023
    YTHDF2 controls hexavalent chromium-induced mitophagy through modulating Hif1alpha and Bnip3 decay via the m[6]A/mRNA pathway in spermatogonial stem cells/progenitors.

    YTHDF2 controls hexavalent chromium-induced mitophagy through modulating Hif1α and Bnip3 decay via the m(6)A/mRNA pathway in spermatogonial stem cells/progenitors.
    Li T, Zheng Y, Wu Z, Guo M, Liu R, Zeng W, Lv Y.

    03/19/2023
    BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy.

    BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy.
    Liu K, Zhao Q, Sun H, Liu L, Wang C, Li Z, Xu Y, Wang L, Zhang L, Zhang H, Chen Q, Zhao T., Free PMC Article

    04/23/2022
    Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy.

    Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy.
    Lin Q, Li S, Jiang N, Jin H, Shao X, Zhu X, Wu J, Zhang M, Zhang Z, Shen J, Zhou W, Gu L, Lu R, Ni Z., Free PMC Article

    04/9/2022
    BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver.

    BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver.
    Springer MZ, Poole LP, Drake LE, Bock-Hughes A, Boland ML, Smith AG, Hart J, Chourasia AH, Liu I, Bozek G, Macleod KF., Free PMC Article

    03/26/2022
    The MAP Kinase Phosphatase MKP-1 Modulates Neurogenesis via Effects on BNIP3 and Autophagy.

    The MAP Kinase Phosphatase MKP-1 Modulates Neurogenesis via Effects on BNIP3 and Autophagy.
    Li Y, Halterman MW., Free PMC Article

    01/22/2022
    Propofol Protects Against Hepatic Ischemia Reperfusion Injury via Inhibiting Bnip3-Mediated Oxidative Stress.

    Propofol Protects Against Hepatic Ischemia Reperfusion Injury via Inhibiting Bnip3-Mediated Oxidative Stress.
    Ma H, Liu Y, Li Z, Yu L, Gao Y, Ye X, Yang B, Li H, Shi J.

    12/25/2021
    Pramipexole attenuates neuronal injury in Parkinson's disease by targeting miR-96 to activate BNIP3-mediated mitophagy.

    Pramipexole attenuates neuronal injury in Parkinson's disease by targeting miR-96 to activate BNIP3-mediated mitophagy.
    Wang DX, Yang Y, Huang XS, Tang JY, Zhang X, Huang HX, Zhou B, Liu B, Xiao HQ, Li XH, Yang P, Zou SC, Liu K, Wang XY, Li XS.

    12/18/2021
    BNIP3-Dependent Mitophagy via PGC1alpha Promotes Cartilage Degradation.

    BNIP3-Dependent Mitophagy via PGC1α Promotes Cartilage Degradation.
    Kim D, Song J, Jin EJ., Free PMC Article

    10/30/2021
    Inhibition of the HIF-1alpha/BNIP3 pathway has a retinal neuroprotective effect.

    Inhibition of the HIF-1α/BNIP3 pathway has a retinal neuroprotective effect.
    Kunimi H, Lee D, Ibuki M, Katada Y, Negishi K, Tsubota K, Kurihara T.

    08/7/2021
    Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice.

    Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice.
    Fuller KNZ, McCoin CS, Allen J, Bell-Glenn S, Koestler DC, Dorn GW, Thyfault JP., Free PMC Article

    07/17/2021
    Isolation of Rab5-positive endosomes reveals a new mitochondrial degradation pathway utilized by BNIP3 and Parkin.

    Isolation of Rab5-positive endosomes reveals a new mitochondrial degradation pathway utilized by BNIP3 and Parkin.
    Hammerling BC, Shires SE, Leon LJ, Cortez MQ, Gustafsson ÅB., Free PMC Article

    07/17/2021
    HIF-1alpha-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury.

    HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury.
    Fu ZJ, Wang ZY, Xu L, Chen XH, Li XX, Liao WT, Ma HK, Jiang MD, Xu TT, Xu J, Shen Y, Song B, Gao PJ, Han WQ, Zhang W., Free PMC Article

    07/10/2021
    MicroRNA-194 acts as a suppressor during abdominal aortic aneurysm via inhibition of KDM3A-mediated BNIP3.

    MicroRNA-194 acts as a suppressor during abdominal aortic aneurysm via inhibition of KDM3A-mediated BNIP3.
    Zhang H, Wang Y, Bian X, Yin H.

    06/26/2021
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