| C5aR2 Deficiency Lessens C5aR1 Distribution and Expression in Neutrophils and Macrophages. | C5aR2 Deficiency Lessens C5aR1 Distribution and Expression in Neutrophils and Macrophages.
Zhang T, Ma N, Wang J, Min X, Wei L, Li K., Free PMC Article | 07/19/2024 |
| C5a-C5AR1 axis as a potential trigger of the rupture of intracranial aneurysms. | C5a-C5AR1 axis as a potential trigger of the rupture of intracranial aneurysms.
Okada A, Shimizu K, Kawashima A, Kayahara T, Itani M, Kurita H, Miyamoto S, Kataoka H, Aoki T., Free PMC Article | 02/14/2024 |
| Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage. | Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage.
Bode M, Herrnstadt GR, Dreher L, Ehnert N, Kirkerup P, Lindenmeyer MT, Meyer-Schwesinger CF, Ehmke H, Köhl J, Huber TB, Krebs CF, Steinmetz OM, Wiech T, Wenzel UO. | 01/6/2024 |
| C5a-C5aR1 induces endoplasmic reticulum stress to accelerate vascular calcification via PERK-eIF2alpha-ATF4-CREB3L1 pathway. | C5a-C5aR1 induces endoplasmic reticulum stress to accelerate vascular calcification via PERK-eIF2α-ATF4-CREB3L1 pathway.
Liu A, Chen Z, Li X, Xie C, Chen Y, Su X, Chen Y, Zhang M, Chen J, Yang T, Shen J, Huang H. | 12/18/2023 |
| Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via activating inosine/A2aR pathway. | Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via activating inosine/A2aR pathway.
Kong LR, Chen XH, Sun Q, Zhang KY, Xu L, Ding L, Zhou YP, Zhang ZB, Lin JR, Gao PJ. | 10/5/2023 |
| Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models. | Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models.
Petrisko TJ, Gargus M, Chu SH, Selvan P, Whiteson KL, Tenner AJ., Free PMC Article | 09/22/2023 |
| C5aR1 activation in mice controls inflammatory eosinophil recruitment and functions in allergic asthma. | C5aR1 activation in mice controls inflammatory eosinophil recruitment and functions in allergic asthma.
Wiese AV, Duhn J, Korkmaz RÜ, Quell KM, Osman I, Ender F, Schröder T, Lewkowich I, Hogan S, Huber-Lang M, Gumprecht F, König P, Köhl J, Laumonnier Y. | 07/7/2023 |
| Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis. | Complement receptor C5aR1 on osteoblasts regulates osteoclastogenesis in experimental postmenopausal osteoporosis.
Bülow JM, Renz N, Haffner-Luntzer M, Fischer V, Schoppa A, Tuckermann J, Köhl J, Huber-Lang M, Ignatius A., Free PMC Article | 10/29/2022 |
| Pharmacological activation of the C5a receptor leads to stimulation of the beta-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzheimer's disease. | Pharmacological activation of the C5a receptor leads to stimulation of the β-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzheimer's disease.
Fella E, Papacharalambous R, Kynigopoulos D, Ioannou M, Derua R, Christodoulou C, Stylianou M, Karaiskos C, Kagiava A, Petroula G, Pierides C, Kyriakou M, Koumas L, Costeas P, Panayiotou E., Free PMC Article | 10/1/2022 |
| Effects of C5a and Receptor CD88 on Glutamate and N-Methyl-D-Aspartic Acid Receptor Expression in the Mouse Model of Optic Neuromyelitis. | Effects of C5a and Receptor CD88 on Glutamate and N-Methyl-D-Aspartic Acid Receptor Expression in the Mouse Model of Optic Neuromyelitis.
Li L, Tang J, Wang H, Liu J, Zhou L., Free PMC Article | 05/14/2022 |
| Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells. | Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells.
Sahu RK, Xavier S, Chauss D, Wang L, Chew C, Taylor R, Stallcup WB, Ma JZ, Kazemian M, Afzali B, Köhl J, Portilla D., Free PMC Article | 05/7/2022 |
| The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion and Colonization of Uropathogenic E. coli. | The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion and Colonization of Uropathogenic E. coli.
Wu KY, Cao B, Wang CX, Yang XL, Zhao SJ, Diao TY, Lin LR, Zhao GX, Zhou W, Yang JR, Li K., Free PMC Article | 04/30/2022 |
| The role of complement C5a receptor in DPSC odontoblastic differentiation and in vivo reparative dentin formation. | The role of complement C5a receptor in DPSC odontoblastic differentiation and in vivo reparative dentin formation.
Irfan M, Kim JH, Marzban H, Reed DA, George A, Cooper LF, Chung S., Free PMC Article | 04/23/2022 |
| Mitochondrial C5aR1 activity in macrophages controls IL-1beta production underlying sterile inflammation. | Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Niyonzima N, Rahman J, Kunz N, West EE, Freiwald T, Desai JV, Merle NS, Gidon A, Sporsheim B, Lionakis MS, Evensen K, Lindberg B, Skagen K, Skjelland M, Singh P, Haug M, Ruseva MM, Kolev M, Bibby J, Marshall O, O'Brien B, Deeks N, Afzali B, Clark RJ, Woodruff TM, Pryor M, Yang ZH, Remaley AT, Mollnes TE, Hewitt SM, Yan B, Kazemian M, Kiss MG, Binder CJ, Halvorsen B, Espevik T, Kemper C., Free PMC Article | 03/12/2022 |
| Vascular Endothelial Cells Produce Coagulation Factors That Control Their Growth via Joint Protease-Activated Receptor and C5a Receptor 1 (CD88) Signaling. | Vascular Endothelial Cells Produce Coagulation Factors That Control Their Growth via Joint Protease-Activated Receptor and C5a Receptor 1 (CD88) Signaling.
Cao D, Strainic MG, Counihan D, Sridar S, An F, Hussain W, Schmaier AH, Nieman M, Medof ME., Free PMC Article | 03/5/2022 |
| Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis. | Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis.
Ortiz-Espinosa S, Morales X, Senent Y, Alignani D, Tavira B, Macaya I, Ruiz B, Moreno H, Remírez A, Sainz C, Rodriguez-Pena A, Oyarbide A, Ariz M, Andueza MP, Valencia K, Teijeira A, Hoehlig K, Vater A, Rolfe B, Woodruff TM, Lopez-Picazo JM, Vicent S, Kochan G, Escors D, Gil-Bazo I, Perez-Gracia JL, Montuenga LM, Lambris JD, Ortiz de Solorzano C, Lecanda F, Ajona D, Pio R. | 02/26/2022 |
| Complement C5a promotes antigen cross-presentation by Peyer's patch monocyte-derived dendritic cells and drives a protective CD8(+) T cell response. | Complement C5a promotes antigen cross-presentation by Peyer's patch monocyte-derived dendritic cells and drives a protective CD8(+) T cell response.
Kim SH, Cho BH, Kim KS, Jang YS. | 02/19/2022 |
| C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera. | C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera.
Silva de França F, Villas-Boas IM, Cogliati B, Woodruff TM, Reis EDS, Lambris JD, Tambourgi DV., Free PMC Article | 10/2/2021 |
| Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock. | Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock.
Chakraborty S, Winkelmann VE, Braumüller S, Palmer A, Schultze A, Klohs B, Ignatius A, Vater A, Fauler M, Frick M, Huber-Lang M., Free PMC Article | 09/18/2021 |
| The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets. | The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets.
Nording H, Baron L, Haberthür D, Emschermann F, Mezger M, Sauter M, Sauter R, Patzelt J, Knoepp K, Nording A, Meusel M, Meyer-Saraei R, Hlushchuk R, Sedding D, Borst O, Eitel I, Karsten CM, Feil R, Pichler B, Erdmann J, Verschoor A, Chavakis E, Chavakis T, von Hundelshausen P, Köhl J, Gawaz M, Langer HF., Free PMC Article | 06/26/2021 |
| Toxoplasma Infection Induces Sustained Up-Regulation of Complement Factor B and C5a Receptor in the Mouse Brain via Microglial Activation: Implication for the Alternative Complement Pathway Activation and Anaphylatoxin Signaling in Cerebral Toxoplasmosis. | Toxoplasma Infection Induces Sustained Up-Regulation of Complement Factor B and C5a Receptor in the Mouse Brain via Microglial Activation: Implication for the Alternative Complement Pathway Activation and Anaphylatoxin Signaling in Cerebral Toxoplasmosis.
Shinjyo N, Hikosaka K, Kido Y, Yoshida H, Norose K., Free PMC Article | 06/26/2021 |
| C5aR1 is a master regulator in Colorectal Tumorigenesis via Immune modulation. | C5aR1 is a master regulator in Colorectal Tumorigenesis via Immune modulation.
Ding P, Li L, Li L, Lv X, Zhou D, Wang Q, Chen J, Yang C, Xu E, Dai W, Zhang X, Wang N, Wang Q, Zhang W, Zhang L, Zhou Y, Gu H, Lei Q, Zhou X, Hu W., Free PMC Article | 05/22/2021 |
| C5a/C5aR1 mediates IMQ-induced psoriasiform skin inflammation by promoting IL-17A production from gammadelta-T cells. | C5a/C5aR1 mediates IMQ-induced psoriasiform skin inflammation by promoting IL-17A production from γδ-T cells.
Zheng QY, Xu F, Yang Y, Sun DD, Zhong Y, Wu S, Li GQ, Gao WW, Wang T, Xu GL, Liang SJ. | 03/6/2021 |
| Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis. | Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis.
van den Bos E, Ambrosy B, Horsthemke M, Walbaum S, Bachg AC, Wettschureck N, Innamorati G, Wilkie TM, Hanley PJ., Free PMC Article | 12/26/2020 |
| The C5a/C5aR1 axis promotes progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia/reperfusion injury. | The C5a/C5aR1 axis promotes progression of renal tubulointerstitial fibrosis in a mouse model of renal ischemia/reperfusion injury.
Peng Q, Wu W, Wu KY, Cao B, Qiang C, Li K, Sacks SH, Zhou W. | 09/26/2020 |