| CELSR1 Risk Alleles in Familial Bicuspid Aortic Valve and Hypoplastic Left Heart Syndrome. | CELSR1 Risk Alleles in Familial Bicuspid Aortic Valve and Hypoplastic Left Heart Syndrome.
Theis JL, Niaz T, Sundsbak RS, Fogarty ZC, Bamlet WR, Hagler DJ, Olson TM. | 05/7/2022 |
| Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multi-ciliated cells. | Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multi-ciliated cells.
Usami FM, Arata M, Shi D, Oka S, Higuchi Y, Tissir F, Takeichi M, Fujimori T. | 07/24/2021 |
| Celsr1 mutations significantly reduced trabecular bone mass and distal tibial cortical thickness. | Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.
Orriss IR, Lanham S, Savery D, Greene NDE, Stanier P, Oreffo R, Copp AJ, Galea GL., Free PMC Article | 09/21/2019 |
| type II spiral ganglion neurons make a distinctive 90 degrees turn towards the cochlear base to synapse with 10-15 outer hair cells. this axon turning event requires planar cell polarity signaling and is disrupted in Vangl2 and Celsr1 knockout mice. | A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.
Ghimire SR, Ratzan EM, Deans MR., Free PMC Article | 07/14/2018 |
| required for ureteric tree growth in early development | Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.
Brzóska HŁ, d'Esposito AM, Kolatsi-Joannou M, Patel V, Igarashi P, Lei Y, Finnell RH, Lythgoe MF, Woolf AS, Papakrivopoulou E, Long DA., Free PMC Article | 11/4/2017 |
| Planar cell polarity phenotype is the cellular basis of the circling behavior in Celsr1 mutants. | Celsr1 coordinates the planar polarity of vestibular hair cells during inner ear development.
Duncan JS, Stoller ML, Francl AF, Tissir F, Devenport D, Deans MR., Free PMC Article | 06/10/2017 |
| Celsr1 is required for the generation of polarity at multiple levels of the mouse oviduct. | Celsr1 is required for the generation of polarity at multiple levels of the mouse oviduct.
Shi D, Komatsu K, Hirao M, Toyooka Y, Koyama H, Tissir F, Goffinet AM, Uemura T, Fujimori T. | 01/24/2015 |
| the second signal, governed by Celsr1, Fzd3, and Vangl2, coordinates polarity between cells in both radial progenitors and ependymal cells (tissue polarity). | A dual role for planar cell polarity genes in ciliated cells.
Boutin C, Labedan P, Dimidschstein J, Richard F, Cremer H, André P, Yang Y, Montcouquiol M, Goffinet AM, Tissir F., Free PMC Article | 11/8/2014 |
| Data describe a novel distribution of Celsr1 protein to the basal surface of neuroepithelial cells within both the early neural tube and a less well-defined group of ventricular zone cells at the midline of the developing spinal cord. | Basal enrichment within neuroepithelia suggests novel function(s) for Celsr1 protein.
Formstone CJ, Moxon C, Murdoch J, Little P, Mason I. | 10/4/2010 |
| Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse. | Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse.
Ravni A, Qu Y, Goffinet AM, Tissir F. | 01/21/2010 |
| Developmental expression profiles of Celsr (Flamingo) genes in the mouse | Developmental expression profiles of Celsr (Flamingo) genes in the mouse.
Tissir F, De-Backer O, Goffinet AM, Lambert de Rouvroit C. | 01/21/2010 |
| Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development | Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.
Shima Y, Copeland NG, Gilbert DJ, Jenkins NA, Chisaka O, Takeichi M, Uemura T. | 01/21/2010 |