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    CNN3 calponin 3 [ Homo sapiens (human) ]

    Gene ID: 1266, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Calponin 3 Acts as a Potential Diagnostic and Prognostic Marker and Promotes Glioma Cell Proliferation, Migration, and Invasion.

    Calponin 3 Acts as a Potential Diagnostic and Prognostic Marker and Promotes Glioma Cell Proliferation, Migration, and Invasion.
    Xie Y, Ding W, Xiang Y, Wang X, Yang J.

    10/29/2022
    Calponin 3 is associated with poor prognosis and regulates proliferation and metastasis in osteosarcoma.

    Calponin 3 is associated with poor prognosis and regulates proliferation and metastasis in osteosarcoma.
    Dai F, Luo F, Zhou R, Zhou Q, Xu J, Zhang Z, Xiao J, Song L., Free PMC Article

    03/27/2021
    CNN3 acts as a potential oncogene in cervical cancer by affecting RPLP1 mRNA expression.

    CNN3 acts as a potential oncogene in cervical cancer by affecting RPLP1 mRNA expression.
    Xia L, Yue Y, Li M, Zhang YN, Zhao L, Lu W, Wang X, Xie X., Free PMC Article

    11/21/2020
    Cnn3 depletion resulted in increased and uncoordinated contractility of stress fibers that often led to breakage of individual actomyosin bundles within the stress fiber network.

    Calponin-3 is critical for coordinated contractility of actin stress fibers.
    Ciuba K, Hawkes W, Tojkander S, Kogan K, Engel U, Iskratsch T, Lappalainen P., Free PMC Article

    10/26/2019
    These results reveal the importance of the MEKK1-calponin-3 signaling pathway to cell contractility.

    MEKK1-dependent phosphorylation of calponin-3 tunes cell contractility.
    Hirata H, Ku WC, Yip AK, Ursekar CP, Kawauchi K, Roy A, Guo AK, Vedula SR, Harada I, Chiam KH, Ishihama Y, Lim CT, Sawada Y, Sokabe M.

    08/5/2017
    overexpressed CNN3 during sonic vibration increases expression of glutamate receptors and promotes functional neural differentiation of human umbilical cords-mesenchymal stem cells.

    Overexpressed Calponin3 by Subsonic Vibration Induces Neural Differentiation of hUC-MSCs by Regulating the Ionotropic Glutamate Receptor.
    Kim HJ, Kim JH, Song YJ, Seo YK, Park JK, Kim CW.

    06/4/2016
    CNN3 as a new pro-invasive protein in trophoblast cells that is induced under low oxygen conditions.

    CNN3 regulates trophoblast invasion and is upregulated by hypoxia in BeWo cells.
    Appel S, Ankerne J, Appel J, Oberthuer A, Mallmann P, Dötsch J., Free PMC Article

    11/14/2015
    Participates in actin stress fiber remodeling

    Calponin 3 regulates stress fiber formation in dermal fibroblasts during wound healing.
    Daimon E, Shibukawa Y, Wada Y.

    04/5/2014
    The mRNA and protein level of calponin-3 were increase expression in brain in patiens with epilepsy.

    Increased expression of calponin-3 in epileptic patients and experimental rats.
    Han Y, Yin H, Xu Y, Zhu Q, Luo J, Wang X, Chen G.

    03/31/2012
    Results indicate that CNN3 regulates actin cytoskeleton rearrangement which is required for the plasma membranes of trophoblasts to become fusion competent.

    Calponin 3 regulates actin cytoskeleton rearrangement in trophoblastic cell fusion.
    Shibukawa Y, Yamazaki N, Kumasawa K, Daimon E, Tajiri M, Okada Y, Ikawa M, Wada Y., Free PMC Article

    03/19/2011
    Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

    Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article

    06/30/2010
    Gene rearrangements of CNN3 is associated with mucosa-associated lymphoid tissue lymphoma.

    Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3.
    Vinatzer U, Gollinger M, Müllauer L, Raderer M, Chott A, Streubel B.

    01/21/2010
    These results suggest a role of calponin 3 in the regulation of Bone morphogenetic proteins -dependent cellular responses.

    Identification of calponin 3 as a novel Smad-binding modulator of BMP signaling expressed in cartilage.
    Haag J, Aigner T.

    01/21/2010
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