| Cathelicidin Antimicrobial Peptide Levels in Atherosclerosis and Myocardial Infarction in Mice and Human. | Cathelicidin Antimicrobial Peptide Levels in Atherosclerosis and Myocardial Infarction in Mice and Human.
Höpfinger A, Schmid A, Karrasch T, Pankuweit S, Schäffler A, Grote K., Free PMC Article | 03/20/2024 |
| Increased LL37 in psoriasis and other inflammatory disorders promotes LDL uptake and atherosclerosis. | Increased LL37 in psoriasis and other inflammatory disorders promotes LDL uptake and atherosclerosis.
Nakamura Y, Kulkarni NN, Takahashi T, Alimohamadi H, Dokoshi T, Liu E, Shia M, Numata T, Luo EW, Gombart AF, Yang X, Secrest P, Gordts PL, Tsimikas S, Wong GC, Gallo RL., Free PMC Article | 03/4/2024 |
| LL-37 improves sepsis-induced acute lung injury by suppressing pyroptosis in alveolar epithelial cells. | LL-37 improves sepsis-induced acute lung injury by suppressing pyroptosis in alveolar epithelial cells.
Wang Q, Wen W, Zhou L, Liu F, Ren X, Yu L, Chen H, Jiang Z. | 02/27/2024 |
| The adipokine C1q/TNF-related protein-3 (CTRP-3) inhibits Toll-like receptor (TLR)-induced expression of Cathelicidin antimicrobial peptide (CAMP) in adipocytes. | The adipokine C1q/TNF-related protein-3 (CTRP-3) inhibits Toll-like receptor (TLR)-induced expression of Cathelicidin antimicrobial peptide (CAMP) in adipocytes.
Karrasch T, Höpfinger A, Schäffler A, Schmid A. | 02/19/2022 |
| Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP. | Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP.
Umeshappa CS, Solé P, Surewaard BGJ, Yamanouchi J, Mohapatra S, Uddin MM, Clarke R, Ortega M, Singha S, Mondal D, Yang Y, Vignali DAA, Serra P, Kubes P, Santamaria P. | 01/29/2022 |
| Deficiency of Cathelicidin Attenuates High-Fat Diet Plus Alcohol-Induced Liver Injury through FGF21/Adiponectin Regulation. | Deficiency of Cathelicidin Attenuates High-Fat Diet Plus Alcohol-Induced Liver Injury through FGF21/Adiponectin Regulation.
Li F, Chen J, Liu Y, Gu Z, Jiang M, Zhang L, Chen SY, Deng Z, McClain CJ, Feng W., Free PMC Article | 01/8/2022 |
| Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy. | Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy.
Ren Z, Pan LL, Huang Y, Chen H, Liu Y, Liu H, Tu X, Liu Y, Li B, Dong X, Pan X, Li H, Fu YV, Agerberth B, Diana J, Sun J., Free PMC Article | 10/30/2021 |
| A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea. | A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea.
Deng Z, Chen M, Liu Y, Xu S, Ouyang Y, Shi W, Jian D, Wang B, Liu F, Li J, Shi Q, Peng Q, Sha K, Xiao W, Liu T, Zhang Y, Zhang H, Wang Q, Sun L, Xie H, Li J., Free PMC Article | 10/30/2021 |
| Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production. | Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production.
Holani R, Babbar A, Blyth GAD, Lopes F, Jijon H, McKay DM, Hollenberg MD, Cobo ER., Free PMC Article | 10/2/2021 |
| Cathelicidin protects mice from Rhabdomyolysis-induced Acute Kidney Injury. | Cathelicidin protects mice from Rhabdomyolysis-induced Acute Kidney Injury.
da Silva BHCS, Ariga SK, Barbeiro HV, Volpini RA, Barbeiro DF, Seguro AC, Pinheiro da Silva F., Free PMC Article | 09/18/2021 |
| Cathelicidin antimicrobial peptides suppress EV71 infection via regulating antiviral response and inhibiting viral binding. | Cathelicidin antimicrobial peptides suppress EV71 infection via regulating antiviral response and inhibiting viral binding.
Yu J, Dai Y, Fu Y, Wang K, Yang Y, Li M, Xu W, Wei L. | 08/28/2021 |
| Cathelicidin deficiency exacerbates cardiac dysfunction in lipopolysaccharide-induced endotoxaemic mice. | Cathelicidin deficiency exacerbates cardiac dysfunction in lipopolysaccharide-induced endotoxaemic mice.
Zhai T, Zhang J, Zhang Y, Wu Y. | 07/17/2021 |
| Distinct contributions of cathelin-related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis. | Distinct contributions of cathelin-related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis.
Chen K, Yoshimura T, Yao X, Gong W, Huang J, Dzutsev AK, McCulloch J, O'hUigin C, Bian XW, Trinchieri G, Wang JM., Free PMC Article | 05/29/2021 |
| Cathelicidin-related antimicrobial peptide alleviates alcoholic liver disease through inhibiting inflammasome activation. | Cathelicidin-related antimicrobial peptide alleviates alcoholic liver disease through inhibiting inflammasome activation.
Li F, Zhao C, Shao T, Liu Y, Gu Z, Jiang M, Li H, Zhang L, Gillevet PM, Puri P, Deng ZB, Chen SY, Barve S, Gobejishvili L, Vatsalya V, McClain CJ, Feng W., Free PMC Article | 03/20/2021 |
| Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection. | Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection.
Patras KA, Coady A, Babu P, Shing SR, Ha AD, Rooholfada E, Brandt SL, Geriak M, Gallo RL, Nizet V., Free PMC Article | 03/20/2021 |
| Efficacy of Antigonococcal CMP-Nonulosonate Therapeutics Require Cathelicidins. | Efficacy of Antigonococcal CMP-Nonulosonate Therapeutics Require Cathelicidins.
Gulati S, Schoenhofen IC, Lindhout-Djukic T, Lewis LA, Moustafa IY, Saha S, Zheng B, Nowak N, Rice PA, Varki A, Ram S., Free PMC Article | 03/13/2021 |
| Cathelicidin aggravates myocardial ischemia/reperfusion injury via activating TLR4 signaling and P2X7R/NLRP3 inflammasome. | Cathelicidin aggravates myocardial ischemia/reperfusion injury via activating TLR4 signaling and P2X(7)R/NLRP3 inflammasome.
Wu Y, Zhang Y, Zhang J, Zhai T, Hu J, Luo H, Zhou H, Zhang Q, Zhou Z, Liu F. | 01/23/2021 |
| Cathelicidins and the Onset of Labour. | Cathelicidins and the Onset of Labour.
Boeckel SRV, Hrabalkova L, Baker TL, MacPherson H, Frew L, Boyle AK, McHugh BJ, Wilson K, Norman JE, Dorin JR, Davidson DJ, Stock SJ., Free PMC Article | 10/24/2020 |
| Peptide LL-37 and its analog sLL-37 attenuated the progression of sepsis-induced acute lung injury by inhibiting neutrophil infiltration and migration through the FAK, ERK, and P38 pathways. | LL-37 and its analog FF/CAP18 attenuate neutrophil migration in sepsis-induced acute lung injury.
Qin X, Zhu G, Huang L, Zhang W, Huang Y, Xi X. | 06/20/2020 |
| ndogenous cathelicidin promotes intestinal barrier integrity accompanied by modulating the infiltration of neutrophils and macrophages in polymicrobial sepsis | Cathelicidin preserves intestinal barrier function in polymicrobial sepsis.
Ho J, Chan H, Liang Y, Liu X, Zhang L, Li Q, Zhang Y, Zeng J, Ugwu FN, Ho IHT, Hu W, Yau JCW, Wong SH, Wong WT, Ling L, Cho CH, Gallo RL, Gin T, Tse G, Yu J, Chan MTV, Leung CCH, Wu WKK., Free PMC Article | 03/21/2020 |
| Altogether, these findings show that C57BL/6 mice can clear the mycobacterial infection early and that this early control is associated with high CRAMP expression in the lungs without concomitant influx of immune cells. | Early Resistance of Non-virulent Mycobacterial Infection in C57BL/6 Mice Is Associated With Rapid Up-Regulation of Antimicrobial Cathelicidin Camp.
Adam L, López-González M, Björk A, Pålsson S, Poux C, Wahren-Herlenius M, Fernández C, Spetz AL., Free PMC Article | 09/21/2019 |
| CRAMP is critical in maintaining colon microbiota balance. | The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance.
Yoshimura T, McLean MH, Dzutsev AK, Yao X, Chen K, Huang J, Gong W, Zhou J, Xiang Y, H Badger J, O'hUigin C, Thovarai V, Tessarollo L, Durum SK, Trinchieri G, Bian XW, Wang JM., Free PMC Article | 02/23/2019 |
| Mice treated with BMMNCs pre-incubated with CRAMP had smaller scars, enhanced cardiac recovery and less adverse remodeling. Histologically, this group had higher capillary density. Similarly, sustained CRAMP release from hydrogels enhanced the therapeutic effect of SDF-1, leading to enhanced functional recovery | Cathelicidin Related Antimicrobial Peptide (CRAMP) Enhances Bone Marrow Cell Retention and Attenuates Cardiac Dysfunction in a Mouse Model of Myocardial Infarction.
Klyachkin YM, Idris A, Rodell CB, Tripathi H, Ye S, Nagareddy P, Asfour A, Gao E, Annabathula R, Ratajczak M, Burdick JA, Abdel-Latif A., Free PMC Article | 12/29/2018 |
| LL-37/CRAMP represents an important mediator of platelet activation and thrombo-inflammation. | Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation.
Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C., Free PMC Article | 12/22/2018 |
| CRAMP deficiency impairs phagocytosis in cultured microglia cells after exposure to N. meningitides. | CRAMP deficiency leads to a pro-inflammatory phenotype and impaired phagocytosis after exposure to bacterial meningitis pathogens.
Kress E, Merres J, Albrecht LJ, Hammerschmidt S, Pufe T, Tauber SC, Brandenburg LO., Free PMC Article | 05/26/2018 |