| Circular RNA circEfnb2 promotes cell injury after cerebral infarction by sponging miR-202-5p and regulating TRAF3 expression. | Circular RNA circEfnb2 promotes cell injury after cerebral infarction by sponging miR-202-5p and regulating TRAF3 expression.
Tu L, Cheng W, Wang X, Li Z, Li X. | 09/20/2024 |
| Inhibition of Ephrin B2 Reverse Signaling Abolishes Multiple Myeloma Pathogenesis. | Inhibition of Ephrin B2 Reverse Signaling Abolishes Multiple Myeloma Pathogenesis.
Sasine JP, Kozlova NY, Valicente L, Dukov J, Tran DH, Himburg HA, Kumar S, Khorsandi S, Chan A, Grohe S, Li M, Kan J, Sehl ME, Schiller GJ, Reinhardt B, Singh BK, Ho R, Yue P, Pasquale EB, Chute JP., Free PMC Article | 03/19/2024 |
| EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS. | EphrinB2 knockdown in cervical spinal cord preserves diaphragm innervation in a mutant SOD1 mouse model of ALS.
Urban MW, Charsar BA, Heinsinger NM, Markandaiah SS, Sprimont L, Zhou W, Brown EV, Henderson NT, Thomas SJ, Ghosh B, Cain RE, Trotti D, Pasinelli P, Wright MC, Dalva MB, Lepore AC., Free PMC Article | 02/16/2024 |
| Transcriptional regulation of the mouse EphA4, Ephrin-B2 and Ephrin-A3 genes by the circadian clock machinery. | Transcriptional regulation of the mouse EphA4, Ephrin-B2 and Ephrin-A3 genes by the circadian clock machinery.
Ballester Roig MN, Roy PG, Hannou L, Delignat-Lavaud B, Sully Guerrier TA, Bélanger-Nelson E, Dufort-Gervais J, Mongrain V. | 09/27/2023 |
| EphrinB2 drives osteogenic fate of adult cardiac fibroblasts in a calcium influx dependent manner. | EphrinB2 drives osteogenic fate of adult cardiac fibroblasts in a calcium influx dependent manner.
Li W, Su SA, Chen J, Shen Y, Ma H, Xiang M. | 06/25/2023 |
| Adaptive activation of EFNB2/EPHB4 axis promotes post-metastatic growth of colorectal cancer liver metastases by LDLR-mediated cholesterol uptake. | Adaptive activation of EFNB2/EPHB4 axis promotes post-metastatic growth of colorectal cancer liver metastases by LDLR-mediated cholesterol uptake.
Xu C, Gu L, Kuerbanjiang M, Jiang C, Hu L, Liu Y, Xue H, Li J, Zhang Z, Xu Q., Free PMC Article | 01/14/2023 |
| Histone deacetylase 4 inhibition ameliorates the social deficits induced by Ephrin-B2 mutation. | Histone deacetylase 4 inhibition ameliorates the social deficits induced by Ephrin-B2 mutation.
Ju P, Chen J, Ma L, Cheng Y, Liu J, Sun Y, Zhu C, Shen Z, Wang W, Peng Y, Ali U, Xu N, Chen J. | 10/29/2022 |
| EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment. | EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
Bhatia S, Nguyen D, Darragh LB, Van Court B, Sharma J, Knitz MW, Piper M, Bukkapatnam S, Gadwa J, Bickett TE, Bhuvane S, Corbo S, Wu B, Lee Y, Fujita M, Joshi M, Heasley LE, Ferris RL, Rodriguez O, Albanese C, Kapoor M, Pasquale EB, Karam SD., Free PMC Article | 06/25/2022 |
| EphrinB2 and GRIP1 stabilize mushroom spines during denervation-induced homeostatic plasticity. | EphrinB2 and GRIP1 stabilize mushroom spines during denervation-induced homeostatic plasticity.
Bissen D, Kracht MK, Foss F, Hofmann J, Acker-Palmer A., Free PMC Article | 01/29/2022 |
| RNA-seq co-expression network analysis reveals anxiolytic behavior of mice with Efnb2 knockout in parvalbumin+ neurons. | RNA-seq co-expression network analysis reveals anxiolytic behavior of mice with Efnb2 knockout in parvalbumin+ neurons.
Sun Y, Ma L, Chen J, Wang W, Peng S, Cheng Y, Zhang Y, Chen J, Ju P., Free PMC Article | 01/22/2022 |
| Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae. | Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae.
Wang T, Liu J, Liu H, Lee SR, Gonzalez L, Gorecka J, Shu C, Dardik A., Free PMC Article | 09/25/2021 |
| A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice. | A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice.
Mattiske D, Behringer RR, Overbeek PA, Pask AJ. | 07/17/2021 |
| EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity. | EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity.
Frye M, Stritt S, Ortsäter H, Hernandez Vasquez M, Kaakinen M, Vicente A, Wiseman J, Eklund L, Martínez-Torrecuadrada JL, Vestweber D, Mäkinen T., Free PMC Article | 02/27/2021 |
| Increased Ephrin-B2 expression in pericytes contributes to retinal vascular death in rodents. | Increased Ephrin-B2 expression in pericytes contributes to retinal vascular death in rodents.
Coucha M, Barrett AC, Bailey J, Abdelghani M, Abdelsaid M. | 10/24/2020 |
| EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development. | EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development.
Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, Segarra M, Ruiz de Almodóvar C, Acker-Palmer A., Free PMC Article | 06/20/2020 |
| we have used mouse genetics, imaging and cell biology approaches to investigate how homeostasis in the adult heart is controlled by endothelial EphB4 and its ligand ephrin-B2, which are known regulators of vascular morphogenesis and arteriovenous differentiation during development. | Endothelial EphB4 maintains vascular integrity and transport function in adult heart.
Luxán G, Stewen J, Díaz N, Kato K, Maney SK, Aravamudhan A, Berkenfeld F, Nagelmann N, Drexler HC, Zeuschner D, Faber C, Schillers H, Hermann S, Wiseman J, Vaquerizas JM, Pitulescu ME, Adams RH., Free PMC Article | 05/16/2020 |
| secondary mineralization involves EphrinB2-RhoA-limited autophagy in osteocytes, and disruption leads to a bone fragility independent of bone mass. | Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone.
Vrahnas C, Blank M, Dite TA, Tatarczuch L, Ansari N, Crimeen-Irwin B, Nguyen H, Forwood MR, Hu Y, Ikegame M, Bambery KR, Petibois C, Mackie EJ, Tobin MJ, Smyth GK, Oakhill JS, Martin TJ, Sims NA., Free PMC Article | 12/21/2019 |
| Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation | Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation.
Dong M, Spelke DP, Lee YK, Chung JK, Yu CH, Schaffer DV, Groves JT., Free PMC Article | 08/31/2019 |
| Production of inflammatory cytokines was inhibited by Ti particles through bidirectional signals. Addition of ephB4Fc inhibited the osteoclastmediated formation of Ti particles via bidirectional ephrinB2/ephB4 signaling. Activation of this bidirectional signaling pathway may be a potential clinical treatment for osteolysis surrounding prostheses. | Titanium particle‑mediated osteoclastogenesis may be attenuated via bidirectional ephrin‑B2/eph‑B4 signaling in vitro.
Ge YW, Liu ZQ, Sun ZY, Yu DG, Feng K, Zhu ZA, Mao YQ., Free PMC Article | 11/10/2018 |
| Results show that early but not late post conditioning hippocampal protein synthesis is necessary for the formation of remote memory and provide the first evidence of a possible involvement of EphrinB2 in neuronal plasticity in the anterior cingulate cortex. | Dendritic spine density and EphrinB2 levels of hippocampal and anterior cingulate cortex neurons increase sequentially during formation of recent and remote fear memory in the mouse.
Abate G, Colazingari S, Accoto A, Conversi D, Bevilacqua A. | 09/8/2018 |
| GRIP1 binds to apoER2 and EphrinB2 to induce activity-dependent AMPA receptor insertion at the synapse. | GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse.
Pfennig S, Foss F, Bissen D, Harde E, Treeck JC, Segarra M, Acker-Palmer A., Free PMC Article | 05/26/2018 |
| Results show that EfnB2 plays a previously unrecognized role as a principal regulator of hematopoiesis from the dorsal aorta and embryonic stem cells by controlling the emergence of hemogenic endothelial cells. During vascular development, EfnB2 is essential for the proper sorting of arterial and venous-fated endothelium into distinct arterial and venous vascular beds. | EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta.
Chen II, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G., Free PMC Article | 04/28/2018 |
| Data reveal that ephrinB2 and ephrinB3 signaling is required to control progenitor identities in the ventral spinal cord. | Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord.
Laussu J, Audouard C, Kischel A, Assis-Nascimento P, Escalas N, Liebl DJ, Soula C, Davy A., Free PMC Article | 03/31/2018 |
| that expression of EFNB1 and EFNB2 is implicated in Th cell differentiation and migration to inflammatory sites in both EAE and MS | EphrinB1 and EphrinB2 regulate T cell chemotaxis and migration in experimental autoimmune encephalomyelitis and multiple sclerosis.
Luo H, Broux B, Wang X, Hu Y, Ghannam S, Jin W, Larochelle C, Prat A, Wu J. | 02/24/2018 |
| As endothelial progenitor cells (EPCs)derived from mouse bone marrow were cultured on substrates of increasing stiffness, the mRNA and protein levels of the specific arterial endothelial cell marker ephrinB2 were found to increase, while the expression of the venous marker EphB4 decreased | Substrate stiffness regulates arterial-venous differentiation of endothelial progenitor cells via the Ras/Mek pathway.
Xue C, Zhang T, Xie X, Zhang Q, Zhang S, Zhu B, Lin Y, Cai X. | 12/9/2017 |