| Single-cell RNA sequencing unveils unique transcriptomic signatures of endothelial cells and role of ENO1 in response to disturbed flow. | Single-cell RNA sequencing unveils unique transcriptomic signatures of endothelial cells and role of ENO1 in response to disturbed flow.
Chen LJ, Li JY, Nguyen P, He M, Chen ZB, Subramaniam S, Shyy JY, Chien S., Free PMC Article | 02/5/2024 |
| Unrevealed roles of extracellular enolase-1 (ENO1) in promoting glycolysis and pro-cancer activities in multiple myeloma via hypoxia-inducible factor 1alpha. | Unrevealed roles of extracellular enolase‑1 (ENO1) in promoting glycolysis and pro‑cancer activities in multiple myeloma via hypoxia‑inducible factor 1α.
Chung IC, Huang WC, Huang YT, Chen ML, Tsai AW, Wu PY, Yuan TT., Free PMC Article | 10/12/2023 |
| ENO1 promotes immunosuppression and tumor growth in pancreatic cancer. | ENO1 promotes immunosuppression and tumor growth in pancreatic cancer.
Huang CK, Lv L, Chen H, Sun Y, Ping Y. | 06/21/2023 |
| TNF-alpha/ENO1 signaling facilitates testicular phagocytosis by directly activating Elmo1 gene expression in mouse Sertoli cells. | TNF-α/ENO1 signaling facilitates testicular phagocytosis by directly activating Elmo1 gene expression in mouse Sertoli cells.
Xiong H, Chen Z, Zhao J, Li W, Zhang S. | 05/28/2022 |
| F. nucleatum targets lncRNA ENO1-IT1 to promote glycolysis and oncogenesis in colorectal cancer. | F. nucleatum targets lncRNA ENO1-IT1 to promote glycolysis and oncogenesis in colorectal cancer.
Hong J, Guo F, Lu SY, Shen C, Ma D, Zhang X, Xie Y, Yan T, Yu T, Sun T, Qian Y, Zhong M, Chen J, Peng Y, Wang C, Zhou X, Liu J, Liu Q, Ma X, Chen YX, Chen H, Fang JY. | 01/15/2022 |
| our data revealed that ENO1 plays a novel and protective role in cerebral ischemia-induced neuronal injury | Enolase1 Alleviates Cerebral Ischemia-Induced Neuronal Injury via Its Enzymatic Product Phosphoenolpyruvate.
Jiang W, Tian X, Yang P, Li J, Xiao L, Liu J, Liu C, Tan W, Tu H. | 07/11/2020 |
| regulates the metabolic reprogramming and malignant phenotype of pulmonary artery smooth muscle cells in pulmonary arterial hypertension | Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway.
Dai J, Zhou Q, Chen J, Rexius-Hall ML, Rehman J, Zhou G., Free PMC Article | 01/19/2019 |
| this paper shows the immunoregulatory role of alpha enolase in dendritic cell function during Chlamydia infection | The immunoregulatory role of alpha enolase in dendritic cell function during Chlamydia infection.
Ryans K, Omosun Y, McKeithen DN, Simoneaux T, Mills CC, Bowen N, Eko FO, Black CM, Igietseme JU, He Q., Free PMC Article | 03/31/2018 |
| Eno1 may be a potential marker for low sperm motility induced by iron ion radiation, and these results may provide a useful reference for changes in astronaut fertility during long space missions. | Comparative proteomics reveals the underlying toxicological mechanism of low sperm motility induced by iron ion radiation in mice.
Li H, He Y, Yan J, Zhao Q, Di C, Zhang H. | 01/6/2018 |
| The results confirmed the altered expression of HFABP, a key fatty acid transport protein, and of enolase and PGK1, the key enzymes in the glycolytic process | Metabolic alterations derived from absence of Two-Pore Channel 1 at cardiac level.
Garcia-Rua V, Feijoo-Bandin S, Garcia-Vence M, Aragon-Herrera A, Bravo SB, Rodriguez-Penas D, Mosquera-Leal A, Lear PV, Parrington J, Alonso J, Rosello-Lleti E, Portoles M, Rivera M, Gonzalez-Juanatey JR, Lago F. | 03/18/2017 |
| Pre-immunization with ENO1 or its immunodominant peptide pEP1 reduces CIA severity at the clinical, immunological and histological levels | Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model.
Guillou C, Derambure C, Fréret M, Verdet M, Avenel G, Golinski ML, Sabourin JC, Le Loarer F, Adriouch S, Boyer O, Lequerré T, Vittecoq O., Free PMC Article | 05/14/2016 |
| a Wnt/beta-catenin-driven functional role of ENO1 and PDIA3 in alveolar epithelial cell plasticity in lung injury and repair, is reported. | Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/β-catenin-driven trans-differentiation of murine alveolar epithelial cells.
Mutze K, Vierkotten S, Milosevic J, Eickelberg O, Königshoff M., Free PMC Article | 04/23/2016 |
| Enolase is a new target of liver X receptors. | Enolase is regulated by Liver X Receptors.
De Boussac H, Maqdasy S, Trousson A, Zelcer N, Volle DH, Lobaccaro JM, Baron S. | 03/12/2016 |
| Alpha-enolase is upregulated on the cell surface and responds to plasminogen activation in mice expressing a 133p53alpha mimic | Alpha-enolase is upregulated on the cell surface and responds to plasminogen activation in mice expressing a ∆133p53α mimic.
Sawhney S, Hood K, Shaw A, Braithwaite AW, Stubbs R, Hung NA, Royds JA, Slatter TL., Free PMC Article | 10/17/2015 |
| MBP1 inhibits Ab fibril formation in vitro and demonstrate the ability of MBP1 to reduce Ab pathology and improve behavioral performance. | N-terminal region of myelin basic protein reduces fibrillar amyloid-β deposition in Tg-5xFAD mice.
Ou-Yang MH, Xu F, Liao MC, Davis J, Robinson JK, Van Nostrand WE., Free PMC Article | 09/28/2015 |
| These data show a multiantibody composition in lupus nephritis, where IgG2 autoantibodies against alpha-enolase and annexin AI predominate in the glomerulus and can be detected in serum. | Glomerular autoimmune multicomponents of human lupus nephritis in vivo: α-enolase and annexin AI.
Bruschi M, Sinico RA, Moroni G, Pratesi F, Migliorini P, Galetti M, Murtas C, Tincani A, Madaio M, Radice A, Franceschini F, Trezzi B, Bianchi L, Giallongo A, Gatti R, Tardanico R, Scaloni A, D'Ambrosio C, Carnevali ML, Messa P, Ravani P, Barbano G, Bianco B, Bonanni A, Scolari F, Martini A, Candiano G, Allegri L, Ghiggeri GM., Free PMC Article | 01/10/2015 |
| These results demonstrate the novel requirement of alpha-enolase for restoring homeostasis of injured muscle tissue, by controlling the pericellular localization of plasmin activity. | Requirement of plasminogen binding to its cell-surface receptor α-enolase for efficient regeneration of normal and dystrophic skeletal muscle.
Díaz-Ramos À, Roig-Borrellas A, García-Melero A, Llorens A, López-Alemany R., Free PMC Article | 06/1/2013 |
| ENO1-positive monocytes and macrophages are found in arthritic ankle tissues of mice with collagen-induced arthritis. | α-Enolase expressed on the surfaces of monocytes and macrophages induces robust synovial inflammation in rheumatoid arthritis.
Bae S, Kim H, Lee N, Won C, Kim HR, Hwang YI, Song YW, Kang JS, Lee WJ. | 09/8/2012 |
| enolase 1 and calreticulin are important proteins in regulating the differentiation and functions of bone marrow mast cells | Enolase 1 and calreticulin regulate the differentiation and function of mouse mast cells.
Ryu SY, Hong GU, Kim DY, Ro JY. | 02/25/2012 |
| the expression of alpha-enolase plasminogen receptor may serve to concentrate and enhance plasmin generation on the cell surface of migratory myoblasts contributing to efficient muscle repair [review] | Alpha-enolase plasminogen receptor in myogenesis.
Lopez-Alemany R, Suelves M, Diaz-Ramos A, Vidal B, Munoz-Canoves P. | 01/21/2010 |
| plasminogen stimulated DNA binding activity of the transcription factors activator-protein 1 and early growth response gene-1 to their cognate regulatory sequences at alpha-enolase promoter | Plasminogen/plasmin regulates alpha-enolase expression through the MEK/ERK pathway.
Sousa LP, Silva BM, Brasil BS, Nogueira SV, Ferreira PC, Kroon EG, Kato K, Bonjardim CA. | 01/21/2010 |
| By concentrating and enhancing plasmin generation on the cell surface, alpha-enolase-type plasminogen receptor is an important component of skeletal myogenesis. | Plasmin generation dependent on alpha-enolase-type plasminogen receptor is required for myogenesis.
López-Alemany R, Suelves M, Muñoz-Cánoves P. | 01/21/2010 |