| H3K18 lactylation accelerates liver fibrosis progression through facilitating SOX9 transcription. | H3K18 lactylation accelerates liver fibrosis progression through facilitating SOX9 transcription.
Wu S, Li J, Zhan Y. | 08/12/2024 |
| SRY-box transcription factor 9 modulates Muller cell gliosis in diabetic retinopathy by upregulating TXNIP transcription. | SRY-box transcription factor 9 modulates Müller cell gliosis in diabetic retinopathy by upregulating TXNIP transcription.
Li S, Ouyang G, Yuan L, Wu X, Zhang L., Free PMC Article | 08/9/2023 |
| Knockdown of SOX9 alleviates tracheal fibrosis through the Wnt/beta-catenin signaling pathway. | Knockdown of SOX9 alleviates tracheal fibrosis through the Wnt/β-catenin signaling pathway.
Gu L, Li A, Lin J, Gan Y, He C, Xiao R, Liao J, Li Y, Guo S. | 10/29/2022 |
| [Repair impact of vibration exercise with different frequencies on articular cartilage of rats with early knee osteoarthritis and its JNK/NF-kappaB, SOX9 mechanisms]. | [Repair impact of vibration exercise with different frequencies on articular cartilage of rats with early knee osteoarthritis and its JNK/NF-κB, SOX9 mechanisms].
Wang ZB, Wang L, Liu QQ, Yang YH, Liu P, Li SL, Yao CF. | 06/11/2022 |
| Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis. | Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis.
Xie M, Wu Z, Ying S, Liu L, Zhao C, Yao C, Zhang Z, Luo C, Wang W, Zhao D, Zhang J, Qiu W, Wang Y., Free PMC Article | 04/2/2022 |
| Neuroprotective effects of miR-30c on rats with cerebral ischemia/reperfusion injury by targeting SOX9. | Neuroprotective effects of miR-30c on rats with cerebral ischemia/reperfusion injury by targeting SOX9.
Zhang M, Zhu Y, Wei M, Liu H. | 10/2/2021 |
| ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia. | ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia.
Gonçalves AN, Correia-Pinto J, Nogueira-Silva C., Free PMC Article | 09/18/2021 |
| Intermittent hypoxia inhibits mandibular cartilage growth with reduced TGF-beta and SOX9 expressions in neonatal rats. | Intermittent hypoxia inhibits mandibular cartilage growth with reduced TGF-β and SOX9 expressions in neonatal rats.
Lekvijittada K, Hosomichi J, Maeda H, Hong H, Changsiripun C, Kuma YI, Oishi S, Suzuki JI, Yoshida KI, Ono T., Free PMC Article | 08/14/2021 |
| Differentiation of adipose-derived stem cells into functional chondrocytes by a small molecule that induces Sox9. | Differentiation of adipose-derived stem cells into functional chondrocytes by a small molecule that induces Sox9.
Lee J, Lee CY, Park JH, Seo HH, Shin S, Song BW, Kim IK, Kim SW, Lee S, Park JC, Lim S, Hwang KC., Free PMC Article | 08/7/2021 |
| lncRNA-CRNDE regulates BMSC chondrogenic differentiation and promotes cartilage repair in osteoarthritis through SIRT1/SOX9. | lncRNA-CRNDE regulates BMSC chondrogenic differentiation and promotes cartilage repair in osteoarthritis through SIRT1/SOX9.
Shi C, Zheng W, Wang J. | 07/17/2021 |
| Combined therapies with exercise, ozone and mesenchymal stem cells improve the expression of HIF1 and SOX9 in the cartilage tissue of rats with knee osteoarthritis. | Combined therapies with exercise, ozone and mesenchymal stem cells improve the expression of HIF1 and SOX9 in the cartilage tissue of rats with knee osteoarthritis.
Asadi S, Farzanegi P, Azarbayjani MA. | 06/12/2021 |
| Sox9 promotes renal tubular epithelialmesenchymal transition and extracellular matrix aggregation via the PI3K/AKT signaling pathway. | Sox9 promotes renal tubular epithelial‑mesenchymal transition and extracellular matrix aggregation via the PI3K/AKT signaling pathway.
Zhang Z, Wu W, Fang X, Lu M, Wu H, Gao C, Xia Z. | 05/1/2021 |
| The therapeutic effect of bone marrow-derived mesenchymal stem cells on osteoarthritis is improved by the activation of the KDM6A/SOX9 signaling pathway caused by exposure to hypoxia. | The therapeutic effect of bone marrow-derived mesenchymal stem cells on osteoarthritis is improved by the activation of the KDM6A/SOX9 signaling pathway caused by exposure to hypoxia.
Zhi Z, Zhang C, Kang J, Wang Y, Liu J, Wu F, Xu G. | 03/20/2021 |
| microRNA-30e up-regulation alleviates myocardial ischemia-reperfusion injury and promotes ventricular remodeling via SOX9 repression. | microRNA-30e up-regulation alleviates myocardial ischemia-reperfusion injury and promotes ventricular remodeling via SOX9 repression.
Cheng N, Li L, Wu Y, Wang M, Yang M, Wei S, Wang R. | 03/6/2021 |
| Progranulin modulates cartilage-specific gene expression via sirtuin 1-mediated deacetylation of the transcription factors SOX9 and P65. | Progranulin modulates cartilage-specific gene expression via sirtuin 1-mediated deacetylation of the transcription factors SOX9 and P65.
Feng D, Kang X, Wang R, Chen H, Zhang K, Feng W, Li H, Zhu Y, Wu S., Free PMC Article | 02/6/2021 |
| Gingival stromal progenitor cells cultured in Platelet rich fibrin had potential osteogenic differentiation ability predicted by the CBF-alpha1/sox9 ratio. | Osteogenic potential of gingival stromal progenitor cells cultured in platelet rich fibrin is predicted by core-binding factor subunit-α1/Sox9 expression ratio ( in vitro).
Nugraha AP, Narmada IB, Ernawati DS, Dinaryanti A, Hendrianto E, Ihsan IS, Riawan W, Rantam FA., Free PMC Article | 09/7/2019 |
| Results show that clustered regularly interspaced short palindromic repeats/Cas9-mediated SOX9 knockout not only inhibitedglial fibrillary acidic protein expression in rat Muller cells but also attenuated cell migration ability. These results suggest that inhibition of SOX9 activity may be a novel therapeutic strategy for reduction of glial cell activity. | CRISPR-mediated SOX9 knockout inhibits GFAP expression in retinal glial (Müller) cells.
Wang X, Shu Q, Ni Y, Xu G. | 02/16/2019 |
| morphological change and SOX9/SCX expression of the cells at the supraspinatus tendon insertion drastically changed during endochondral ossification | Three-dimensional ultrastructural analysis of development at the supraspinatus insertion by using focused ion beam/scanning electron microscope tomography in rats.
Kanazawa T, Gotoh M, Ohta K, Shiba N, Nakamura K. | 09/23/2017 |
| These findings suggest a novel mechanism of action of SOX5/6; namely, the SOX9/5/6 combination enhances Col2a1 transcription through a novel enhancer in intron 6 together with the enhancer in intron 1. | A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6.
Yasuda H, Oh CD, Chen D, de Crombrugghe B, Kim JH., Free PMC Article | 06/3/2017 |
| Sox9 expression is necessary for chondrocyte differentiation of mesenchymal stem cells by silencing of endogenous Sox9 expression with extracellular-signal-regulated kinase 5 pathway or overexpressing exogenous Sox9. | Sox9-induced chondrogenesis in mesenchymal stem cells was mediated by ERK5 signal pathway.
Wang C, Zhang T, Liu W, Meng H, Song Y, Wang W. | 12/17/2016 |
| These data provide evidence for EPIM and SOX9 functioning by mutual negative feedback to regulate attributes of the quiescent or activated state of HSCs. | Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells.
Pritchett J, Athwal VS, Harvey E, Martin K, Llewellyn J, Ireland P, Nicolaides A, Humphries MJ, Bobola N, Hanley NA, Piper Hanley K., Free PMC Article | 10/10/2015 |
| a spatially loaded combination of RUNX2 and SOX trio DNA loading significantly improved healing relative to empty hydrogels or either factor alone. | Osteochondral tissue regeneration through polymeric delivery of DNA encoding for the SOX trio and RUNX2.
Needham CJ, Shah SR, Dahlin RL, Kinard LA, Lam J, Watson BM, Lu S, Kasper FK, Mikos AG., Free PMC Article | 05/16/2015 |
| the involvement of SOX9 in acquired retinal degeneration triggered by light damage, which might provide novel insights into possible molecular mechanisms that would account for the involvement of Muller cells in retinal degenerative diseases. | Upregulation of SOX9 in Glial (Müller) cells in retinal light damage of rats.
Wang X, Fan J, Zhang M, Ni Y, Xu G. | 02/15/2014 |
| Sox9 is an important link between differentiation, proliferation and apoptosis in undifferentiated adult rat mesenchymal stem cells. | Sox9 modulates cell survival and adipogenic differentiation of multipotent adult rat mesenchymal stem cells.
Stöckl S, Bauer RJ, Bosserhoff AK, Göttl C, Grifka J, Grässel S. | 01/18/2014 |
| Sox9 silencing induced the expression of osteocalcin, Vegfalpha and Mmp13, and decreased rASC proliferation accompanied with an induction of p21 and cyclin D1 expression and delayed S-phase entry. | Sox9 Modulates proliferation and expression of osteogenic markers of adipose-derived stem cells (ASC).
Stöckl S, Göttl C, Grifka J, Grässel S. | 12/21/2013 |