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    CSF3R colony stimulating factor 3 receptor [ Homo sapiens (human) ]

    Gene ID: 1441, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Interactions of the CSF3R polymorphism and early stress on future orientation: evidence for the differential model of stress-related growth.

    Interactions of the CSF3R polymorphism and early stress on future orientation: evidence for the differential model of stress-related growth.
    Gan Y, Wang L, Chen Y, Zheng L, Wu X, Chen G, Hu Y., Free PMC Article

    10/11/2024
    Enhanced MAPK signaling induced by CSF3R mutants confers dependence to DUSP1 for leukemic transformation.

    Enhanced MAPK signaling induced by CSF3R mutants confers dependence to DUSP1 for leukemic transformation.
    Kesarwani M, Kincaid Z, Azhar M, Azam M., Free PMC Article

    09/30/2024
    Identification of CSF3R Mutations in B-Lineage Acute Lymphoblastic Leukemia Using Comprehensive Cancer Panel and Next-Generation Sequencing.

    Identification of CSF3R Mutations in B-Lineage Acute Lymphoblastic Leukemia Using Comprehensive Cancer Panel and Next-Generation Sequencing.
    Rashid M, Alasiri A, Al Balwi MA, Alkhaldi A, Alsuhaibani A, Alsultan A, Alharbi T, Alomair L, Almuzzaini B., Free PMC Article

    08/30/2024
    CSF3R mutated myeloid neoplasms: Beyond chronic neutrophilic leukemia.

    CSF3R mutated myeloid neoplasms: Beyond chronic neutrophilic leukemia.
    Mohamed A, Gao J, Chen YH, Abaza Y, Altman J, Jennings L, Vormittag-Nocito E, Sukhanova M, Lu X, Chen Q.

    07/19/2024
    Analysis of CSF3R mutations in atypical chronic myeloid leukemia and other myeloid malignancies.

    Analysis of CSF3R mutations in atypical chronic myeloid leukemia and other myeloid malignancies.
    Kim SY, Song IC, Kim J, Kwon GC.

    06/17/2024
    Gene Expression of CSF3R/CD114 Is Associated with Poorer Patient Survival in Glioma.

    Gene Expression of CSF3R/CD114 Is Associated with Poorer Patient Survival in Glioma.
    Bark SA, Dalmolin M, Malafaia O, Roesler R, Fernandes MAC, Isolan GR., Free PMC Article

    03/20/2024
    The RNA m[6]A demethylase ALKBH5 drives emergency granulopoiesis and neutrophil mobilization by upregulating G-CSFR expression.

    The RNA m(6)A demethylase ALKBH5 drives emergency granulopoiesis and neutrophil mobilization by upregulating G-CSFR expression.
    Liu Y, Song R, Lu Z, Zhao L, Zhan X, Li Y, Cao X., Free PMC Article

    01/5/2024
    Integrated transcriptome, proteome and single-cell sequencing uncover the prognostic and immunological features of colony-stimulating factor 3 receptor in pan-cancer.

    Integrated transcriptome, proteome and single-cell sequencing uncover the prognostic and immunological features of colony-stimulating factor 3 receptor in pan-cancer.
    Song L, Jiang F, Tian Y, Cao X, Zhu M, Zhang J, Wang X, Deng L.

    11/1/2023
    [Analysis of CSF3R Gene Mutations and Clinical Characteristics in Patients with t(8;21) Acute Myeloid Leukemia].

    [Analysis of CSF3R Gene Mutations and Clinical Characteristics in Patients with t(8;21) Acute Myeloid Leukemia].
    Cui M, Li QY, Lu XZ, Chao HY, Cai XH, Liu J, Hua HY, Wu P.

    08/9/2023
    Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity.

    Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity.
    Hollander MJ, Malaker SA, Riley NM, Perez I, Abney NM, Gray MA, Maxson JE, Cochran JR, Bertozzi CR., Free PMC Article

    07/3/2023
    [Restratifying the prognosis of acute myeloid leukemia patients with CEBPA double mutations based on CSF3R mutations and measurable residual disease].

    [Restratifying the prognosis of acute myeloid leukemia patients with CEBPA double mutations based on CSF3R mutations and measurable residual disease].
    Su L, Tan YH, Lin H, Han W, Yang YP, Liu XL, Sun JN, Liu QJ, Gao SJ., Free PMC Article

    02/4/2023
    Alternatively spliced CSF3R isoforms in SRSF2 P95H mutated myeloid neoplasms.

    Alternatively spliced CSF3R isoforms in SRSF2 P95H mutated myeloid neoplasms.
    Wang BA, Mehta HM, Penumutchu SR, Tolbert BS, Cheng C, Kimmel M, Haferlach T, Maciejewski JP, Corey SJ.

    10/8/2022
    Differential Implications of CSF3R Mutations in t(8;21) and CEBPA Double Mutated Acute Myeloid Leukemia.

    Differential Implications of CSF3R Mutations in t(8;21) and CEBPA Double Mutated Acute Myeloid Leukemia.
    Wang B, Wen L, Wang Z, Chen S, Qiu H.

    07/9/2022
    The prognostic factors in acute myeloid leukaemia with double-mutated CCAAT/enhancer-binding protein alpha (CEBPAdm).

    The prognostic factors in acute myeloid leukaemia with double-mutated CCAAT/enhancer-binding protein alpha (CEBPAdm).
    Wei H, Zhou C, Liu B, Lin D, Li Y, Wei S, Gong B, Zhang G, Liu K, Gong X, Fang Q, Liu Y, Qiu S, Gu R, Song Z, Chen J, Yang M, Zhang J, Jin J, Wang Y, Mi Y, Wang J.

    05/14/2022
    The clinical characteristics and prognosis of Chinese acute myeloid leukemia patients with CSF3R mutations.

    The clinical characteristics and prognosis of Chinese acute myeloid leukemia patients with CSF3R mutations.
    Chen X, Xu J, Fang F, Xu Z, Tan Y, Chang J, Muyey DM, Wang H.

    04/16/2022
    CSF3R T618I mutant chronic myelomonocytic leukemia (CMML) defines a proliferative CMML subtype enriched in ASXL1 mutations with adverse outcomes.

    CSF3R T618I mutant chronic myelomonocytic leukemia (CMML) defines a proliferative CMML subtype enriched in ASXL1 mutations with adverse outcomes.
    Bezerra ED, Lasho TL, Finke CM, Saliba AN, Elliott MA, Pardanani AD, Gangat N, Mangaonkar AA, Ketterling RP, Tefferi A, Solary E, Patnaik MM., Free PMC Article

    01/8/2022
    Colony-stimulating factor 3 signaling in colon and rectal cancers: Immune response and CMS classification in TCGA data.

    Colony-stimulating factor 3 signaling in colon and rectal cancers: Immune response and CMS classification in TCGA data.
    Saunders AS, Bender DE, Ray AL, Wu X, Morris KT., Free PMC Article

    08/28/2021
    Effect of the unfolded protein response and oxidative stress on mutagenesis in CSF3R: a model for evolution of severe congenital neutropenia to myelodysplastic syndrome/acute myeloid leukemia.

    Effect of the unfolded protein response and oxidative stress on mutagenesis in CSF3R: a model for evolution of severe congenital neutropenia to myelodysplastic syndrome/acute myeloid leukemia.
    Sapra A, Jaksik R, Mehta H, Biesiadny S, Kimmel M, Corey SJ., Free PMC Article

    08/21/2021
    Heterozygous germ line CSF3R variants as risk alleles for development of hematologic malignancies.

    Heterozygous germ line CSF3R variants as risk alleles for development of hematologic malignancies.
    Trottier AM, Druhan LJ, Kraft IL, Lance A, Feurstein S, Helgeson M, Segal JP, Das S, Avalos BR, Godley LA., Free PMC Article

    07/17/2021
    Loss-of-function mutations in CSF3R cause moderate neutropenia with fully mature neutrophils: two novel pedigrees.

    Loss-of-function mutations in CSF3R cause moderate neutropenia with fully mature neutrophils: two novel pedigrees.
    Sprenkeler EGG, Tool ATJ, Kreft IC, van Alphen FPJ, NBR-RD PID Consortium, NIHR BioResource, Seneviratne SL, Maimaris J, Luqmani A, van Leeuwen K, van Bruggen R, Burns SO, Kuijpers TW.

    03/28/2021
    Promoter hypermethylation in CSF3R induces peripheral neutrophil reduction in benzene-exposure poisoning.

    Promoter hypermethylation in CSF3R induces peripheral neutrophil reduction in benzene-exposure poisoning.
    Ren JC, Wang T, Wu H, Zhang GH, Sun D, Guo K, Li H, Zhang F, Wu W, Xia ZL.

    01/9/2021
    Next-generation sequencing reveals unique combination of mutations in cis of CSF3R in atypical chronic myeloid leukemia.

    Next-generation sequencing reveals unique combination of mutations in cis of CSF3R in atypical chronic myeloid leukemia.
    Yun JW, Yoon J, Jung CW, Lee KO, Kim JW, Kim SH, Kim HJ., Free PMC Article

    12/19/2020
    Cooperating, congenital neutropenia-associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs.

    Cooperating, congenital neutropenia-associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs.
    Ritter M, Klimiankou M, Klimenkova O, Schambach A, Hoffmann D, Schmidt A, Kanz L, Link DC, Welte K, Skokowa J., Free PMC Article

    10/3/2020
    these data are the first to demonstrate expression of the CSF3R-V3 splice variant in primary human myeloid cells and a role for SRSF2 in modulating CSF3R splicing

    Altered expression of CSF3R splice variants impacts signal response and is associated with SRSF2 mutations.
    Lance A, Druhan LJ, Vestal CG, Steuerwald NM, Hamilton A, Smith M, Price A, Tjaden E, Fox AN, Avalos BR.

    08/1/2020
    CSF3R T618I mutation is associated with familial chronic neutrophilic leukemia.

    Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia.
    Duployez N, Willekens C, Plo I, Marceau-Renaut A, de Botton S, Fenwarth L, Boyer T, Huet G, Nibourel O, Rose C, Nelken B, Quesnel B, Preudhomme C.

    04/18/2020
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