| Astrocyte S100beta expression and selective differentiation to GFAP and GS in the entorhinal cortex during ageing in the 3xTg-Alzheimer's disease mouse model. | Astrocyte S100β expression and selective differentiation to GFAP and GS in the entorhinal cortex during ageing in the 3xTg-Alzheimer's disease mouse model.
Rodríguez JJ, Gardenal E, Zallo F, Arrue A, Cabot J, Busquets X. | 02/13/2024 |
| Large-scale gene expression changes in APP/PSEN1 and GFAP mutation models exhibit high congruence with Alzheimer's disease. | Large-scale gene expression changes in APP/PSEN1 and GFAP mutation models exhibit high congruence with Alzheimer's disease.
Gammie SC, Messing A, Hill MA, Kelm-Nelson CA, Hagemann TL., Free PMC Article | 02/1/2024 |
| Fate Specification of GFAP-Negative Primitive Neural Stem Cells and Their Progeny at Clonal Resolution. | Fate Specification of GFAP-Negative Primitive Neural Stem Cells and Their Progeny at Clonal Resolution.
Yammine SZ, Burns I, Gosio J, Peluso A, Merritt DM, Innes B, Coles BLK, Yan WR, Bader GD, Morshead CM, van der Kooy D. | 10/5/2023 |
| STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease. | STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease.
Hagemann TL, Coyne S, Levin A, Wang L, Feany MB, Messing A., Free PMC Article | 04/19/2023 |
| GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming. | GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming.
Duan S, Sawyer TW, Sontz RA, Wieland BA, Diaz AF, Merchant JL., Free PMC Article | 10/29/2022 |
| Selective Depletion of Adult GFAP-Expressing Tanycytes Leads to Hypogonadotropic Hypogonadism in Males. | Selective Depletion of Adult GFAP-Expressing Tanycytes Leads to Hypogonadotropic Hypogonadism in Males.
Butruille L, Batailler M, Cateau ML, Sharif A, Leysen V, Prévot V, Vaudin P, Pillon D, Migaud M., Free PMC Article | 04/9/2022 |
| RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Muller glial cell hypertrophy in progressive retinal degeneration. | RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Müller glial cell hypertrophy in progressive retinal degeneration.
Hippert C, Graca AB, Basche M, Kalargyrou AA, Georgiadis A, Ribeiro J, Matsuyama A, Aghaizu N, Bainbridge JW, Smith AJ, Ali RR, Pearson RA. | 03/19/2022 |
| Evaluation of Traumatic Spinal Cord Injury in a Rat Model Using (99m)Tc-GA-5 as a Potential In Vivo Tracer. | Evaluation of Traumatic Spinal Cord Injury in a Rat Model Using (99m)Tc-GA-5 as a Potential In Vivo Tracer.
Izquierdo-Sánchez V, Zambrano-Rodríguez PC, Peña-Merino N, Bolaños-Puchet S, Reyes-Alva HJ, Martínez-Cruz A, Muñiz-Hernández S, Guízar-Sahagún G, Medina LA., Free PMC Article | 02/12/2022 |
| Folic acid ameliorates neonatal isolation-induced autistic like behaviors in rats: epigenetic modifications of BDNF and GFAP promotors. | Folic acid ameliorates neonatal isolation-induced autistic like behaviors in rats: epigenetic modifications of BDNF and GFAP promotors.
Ahmed OG, Shehata GA, Ali RM, Makboul R, Abd Allah ESH, Abd El-Rady NM. | 01/8/2022 |
| Reduced GFAP Expression in Bergmann Glial Cells in the Cerebellum of Sigma-1 Receptor Knockout Mice Determines the Neurobehavioral Outcomes after Traumatic Brain Injury. | Reduced GFAP Expression in Bergmann Glial Cells in the Cerebellum of Sigma-1 Receptor Knockout Mice Determines the Neurobehavioral Outcomes after Traumatic Brain Injury.
Stelfa G, Vavers E, Svalbe B, Serzants R, Miteniece A, Lauberte L, Grinberga S, Gukalova B, Dambrova M, Zvejniece L., Free PMC Article | 12/25/2021 |
| Complex and regional-specific changes in the morphological complexity of GFAP(+) astrocytes in middle-aged mice. | Complex and regional-specific changes in the morphological complexity of GFAP(+) astrocytes in middle-aged mice.
Bondi H, Bortolotto V, Canonico PL, Grilli M. | 11/13/2021 |
| GFAP and desmin expression in lymphatic tissues leads to difficulties in distinguishing between glial and stromal cells. | GFAP and desmin expression in lymphatic tissues leads to difficulties in distinguishing between glial and stromal cells.
Günther HS, Henne S, Oehlmann J, Urban J, Pleizier D, Renevier N, Lohr C, Wülfing C., Free PMC Article | 11/6/2021 |
| GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice. | GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice.
Yuan W, Lu L, Rao M, Huang Y, Liu CE, Liu S, Zhao Y, Liu H, Zhu J, Chao T, Wu C, Ren J, Lv L, Li W, Qi S, Liang Y, Yue S, Gao J, Zhang Z, Kong E., Free PMC Article | 10/30/2021 |
| GSK3beta overexpression driven by GFAP promoter improves rotarod performance. | GSK3β overexpression driven by GFAP promoter improves rotarod performance.
Jurado-Arjona J, Rodríguez-Matellán A, Ávila J, Hernández F. | 09/12/2020 |
| assessed the locomotor and exploratory behavior of GFAP-/-Vim-/- mice, their learning, memory and memory extinction, by using the open field, object recognition and Morris water maze tests, trace fear conditioning, and by recording reversal learning in IntelliCages | The role of GFAP and vimentin in learning and memory.
Wilhelmsson U, Pozo-Rodrigalvarez A, Kalm M, de Pablo Y, Widestrand Å, Pekna M, Pekny M. | 02/22/2020 |
| The Alexander disease(AxD) patient iPSC-derived astrocytes recapitulate key features of AxD pathology such as GFAP aggregation. | GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease.
Li L, Tian E, Chen X, Chao J, Klein J, Qu Q, Sun G, Sun G, Huang Y, Warden CD, Ye P, Feng L, Li X, Cui Q, Sultan A, Douvaras P, Fossati V, Sanjana NE, Riggs AD, Shi Y., Free PMC Article | 10/5/2019 |
| Study demonstrated that protein citrullination, along with upregulation and an increase in peptidylarginine deiminase, occur in a widely used bile duct ligation (BDL) mouse model of hepatic fibrosis. Expression level of GFAP and the amount of cit-GFAP were higher in BDL livers than in control livers. In correlation with PAD2 localization, cit-GFAP was observed in alpha-SMA-positive and CK19-positive cells in the livers. | Accumulation of citrullinated glial fibrillary acidic protein in a mouse model of bile duct ligation-induced hepatic fibrosis.
Kim SE, Park JW, Kim MJ, Jang B, Jeon YC, Kim HJ, Ishigami A, Kim HS, Suk KT, Kim DJ, Park CK, Choi EK, Jang MK., Free PMC Article | 02/2/2019 |
| The results indicate that finely tuned levels of Lmnb1 are required for neural stem cells differentiation into neurons, proper expression of the astrocytic marker GFAP and corticogenesis. | Lamin B1 levels modulate differentiation into neurons during embryonic corticogenesis.
Mahajani S, Giacomini C, Marinaro F, De Pietri Tonelli D, Contestabile A, Gasparini L., Free PMC Article | 01/12/2019 |
| The results suggest that BRG1 and STAT3 coordinately regulate gene clustering and up-regulate Gfap and Osmr transcription in astrocytes. | Gfap and Osmr regulation by BRG1 and STAT3 via interchromosomal gene clustering in astrocytes.
Ito K, Noguchi A, Uosaki Y, Taga T, Arakawa H, Takizawa T., Free PMC Article | 01/12/2019 |
| This report the successful prediction and validation of Gfap as an miR-3099 target gene using a combination of bioinformatics resources with enrichment of annotations based on functional ontologies and a spatio-temporal expression dataset. | In Silico Prediction and Validation of Gfap as an miR-3099 Target in Mouse Brain.
Abidin SZ, Leong JW, Mahmoudi M, Nordin N, Abdullah S, Cheah PS, Ling KH., Free PMC Article | 04/21/2018 |
| These results indicate that autoantibodies against GFAP could serve as a predictive marker for the development of overt autoimmune diabetes. | Glial fibrillary acidic protein (GFAP) is a novel biomarker for the prediction of autoimmune diabetes.
Pang Z, Kushiyama A, Sun J, Kikuchi T, Yamazaki H, Iwamoto Y, Koriyama H, Yoshida S, Shimamura M, Higuchi M, Kawano T, Takami Y, Rakugi H, Morishita R, Nakagami H. | 10/14/2017 |
| GFAP is specifically expressed in the auricular chondrocytes, and assumes a pivotal role in resistance against mechanical stress. | Biological roles of glial fibrillary acidic protein as a biomarker in cartilage regenerative medicine.
Kanazawa S, Nishizawa S, Takato T, Hoshi K. | 09/23/2017 |
| compared open-skull and thinned-skull imaging methods for two-photon laser microscopy of live astrocytes in neocortex of GFAP-GFP transgenic mice | In Vivo Two-Photon Imaging of Astrocytes in GFAP-GFP Transgenic Mice.
Guo D, Zou J, Rensing N, Wong M., Free PMC Article | 08/12/2017 |
| work reveals that an Alexander disease-causing mutation alters GFAP turnover kinetics in vivo and provides an essential foundation for future studies aimed at preventing or reducing the accumulation of GFAP. | Glial fibrillary acidic protein exhibits altered turnover kinetics in a mouse model of Alexander disease.
Moody LR, Barrett-Wilt GA, Sussman MR, Messing A., Free PMC Article | 06/3/2017 |
| Tat expression or GFAP expression led to formation of GFAP aggregates and induction of unfolded protein response (UPR) and endoplasmic reticulum (ER) stress in astrocytes. | HIV-1 Tat Induces Unfolded Protein Response and Endoplasmic Reticulum Stress in Astrocytes and Causes Neurotoxicity through Glial Fibrillary Acidic Protein (GFAP) Activation and Aggregation.
Fan Y, He JJ., Free PMC Article | 05/27/2017 |