| Cylindromatosis lysine 63 deubiquitinase (CYLD) suppress TLR3-mediated CCL5 expression in human renal proximal tubular epithelial cells. | Cylindromatosis lysine 63 deubiquitinase (CYLD) suppress TLR3-mediated CCL5 expression in human renal proximal tubular epithelial cells.
Tachizaki M, Kobori Y, Kawaguchi S, Seya K, Tanaka H, Imaizumi T. | 09/17/2024 |
| Cyld restrains the hyperactivation of synovial fibroblasts in inflammatory arthritis by regulating the TAK1/IKK2 signaling axis. | Cyld restrains the hyperactivation of synovial fibroblasts in inflammatory arthritis by regulating the TAK1/IKK2 signaling axis.
Rinotas V, Iliaki K, Pavlidi L, Meletakos T, Mosialos G, Armaka M., Free PMC Article | 08/21/2024 |
| Megalosplenia as an initial manifestation of multiple myeloma with a novel CYLD gene mutation: A case report and literature review. | Megalosplenia as an initial manifestation of multiple myeloma with a novel CYLD gene mutation: A case report and literature review.
Zhang J, Zhang R., Free PMC Article | 04/16/2024 |
| TNF and IFNgamma-induced cell death requires IRF1 and ELAVL1 to promote CASP8 expression. | TNF and IFNγ-induced cell death requires IRF1 and ELAVL1 to promote CASP8 expression.
Deng B, Wang J, Yang T, Deng Z, Yuan J, Zhang B, Zhou Z, Chen F, Fang L, Liang C, Yan B, Ai Y., Free PMC Article | 02/12/2024 |
| CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma. | CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma.
Li Y, Yang C, Xie L, Shi F, Tang M, Luo X, Liu N, Hu X, Zhu Y, Bode AM, Gao Q, Zhou J, Fan J, Li X, Cao Y., Free PMC Article | 02/7/2024 |
| CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression. | CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression.
Gu Y, Wu S, Fan J, Meng Z, Gao G, Liu T, Wang Q, Xia H, Wang X, Wu K., Free PMC Article | 01/29/2024 |
| YTHDC2 Retards Cell Proliferation and Triggers Apoptosis in Papillary Thyroid Cancer by Regulating CYLD-Mediated Inactivation of Akt Signaling. | YTHDC2 Retards Cell Proliferation and Triggers Apoptosis in Papillary Thyroid Cancer by Regulating CYLD-Mediated Inactivation of Akt Signaling.
Zhou G, Wang S. | 01/26/2024 |
| An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses. | An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct inflammatory responses.
Cheng N, Trejo J., Free PMC Article | 01/9/2024 |
| Expanding CYLD protein in NF-kappabeta/TNF-alpha signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients. | Expanding CYLD protein in NF-κβ/TNF-α signaling pathway in response to Lactobacillus acidophilus in non-metastatic rectal cancer patients.
Zamani F, Khalighfard S, Kalhori MR, Poorkhani A, Amiriani T, Hosseinzadeh P, Esmati E, Alemrajabi M, Nikoofar A, Safarnezhad Tameshkel F, Alizadeh AM. | 09/22/2023 |
| CYLD stimulates macrophage phagocytosis of leukemic cells through STAT1 signalling in acute myeloid leukemia. | CYLD stimulates macrophage phagocytosis of leukemic cells through STAT1 signalling in acute myeloid leukemia.
Huyen NT, Ngoc NT, Giang NH, Trang DT, Hanh HH, Binh VD, Giang NV, Canh NX, Xuan NT., Free PMC Article | 08/9/2023 |
| The Potential of Cylindromatosis (CYLD) as a Therapeutic Target in Oxidative Stress-Associated Pathologies: A Comprehensive Evaluation. | The Potential of Cylindromatosis (CYLD) as a Therapeutic Target in Oxidative Stress-Associated Pathologies: A Comprehensive Evaluation.
Huang Z, Tan Y., Free PMC Article | 05/22/2023 |
| MALT1-dependent cleavage of CYLD promotes NF-kappaB signaling and growth of aggressive B-cell receptor-dependent lymphomas. | MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas.
Minderman M, Lantermans HC, Grüneberg LJ, Cillessen SAGM, Bende RJ, van Noesel CJM, Kersten MJ, Pals ST, Spaargaren M., Free PMC Article | 03/22/2023 |
| CYLD variants identified in Alzheimer's disease and frontotemporal dementia patients. | CYLD variants identified in Alzheimer's disease and frontotemporal dementia patients.
Xiao X, Xu T, Liu H, Liu X, Liao X, Zhou Y, Zhou L, Wang X, Zhu Y, Yang Q, Hao X, Liu Y, Jiang H, Guo J, Wang J, Tang B, Li J, Shen L, Jiao B., Free PMC Article | 10/15/2022 |
| CYLD expression in endometrial carcinoma and correlation with clinicohistopathological parameters. | CYLD expression in endometrial carcinoma and correlation with clinicohistopathological parameters.
Papadatou V, Tologkos S, Tsolou A, Deftereou TE, Liberis A, Trypsianis G, Alexiadis T, Georgiadi K, Alexiadi CA, Nikolaidou C, Lambropoulou M. | 07/23/2022 |
| Prevalence of CYLD mutations in Vietnamese patients with polycythemia vera. | Prevalence of CYLD mutations in Vietnamese patients with polycythemia vera.
Trang DT, Giang NH, Trang BK, Ngoc NT, Giang NV, Canh NX, Vuong NB, Xuan NT. | 05/14/2022 |
| CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3. | CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3.
Wang L, Lin Y, Zhou X, Chen Y, Li X, Luo W, Zhou Y, Cai L. | 04/30/2022 |
| TRAF3 and NBR1 both influence the effect of the disease-causing CYLD(Arg936X) mutation on NF-kappaB activity. | TRAF3 and NBR1 both influence the effect of the disease-causing CYLD(Arg936X) mutation on NF-κB activity.
Danis J, Kelemen E, Rajan N, Nagy N, Széll M, Ádám É. | 04/9/2022 |
| SOX4 induces drug resistance of colorectal cancer cells by downregulating CYLD through transcriptional activation of microRNA-17. | SOX4 induces drug resistance of colorectal cancer cells by downregulating CYLD through transcriptional activation of microRNA-17.
Pan S, Bao D, Li Y, Liu D, Quan S, Wang R. | 04/2/2022 |
| Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-kappaB Pathway. | Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Wang J, Tan L, Jia B, Yu X, Yao R, OUYang N, Yu X, Cao X, Tong J, Chen T, Chen R, Li J., Free PMC Article | 03/19/2022 |
| Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains. | Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Elliott PR, Leske D, Wagstaff J, Schlicher L, Berridge G, Maslen S, Timmermann F, Ma B, Fischer R, Freund SMV, Komander D, Gyrd-Hansen M., Free PMC Article | 02/19/2022 |
| CYLD destabilizes NoxO1 protein by promoting ubiquitination and regulates prostate cancer progression. | CYLD destabilizes NoxO1 protein by promoting ubiquitination and regulates prostate cancer progression.
Haq S, Sarodaya N, Karapurkar JK, Suresh B, Jo JK, Singh V, Bae YS, Kim KS, Ramakrishna S. | 01/8/2022 |
| CYLD mediates human pulmonary artery smooth muscle cell dysfunction in congenital heart disease-associated pulmonary arterial hypertension. | CYLD mediates human pulmonary artery smooth muscle cell dysfunction in congenital heart disease-associated pulmonary arterial hypertension.
Zhou JJ, Li H, Li L, Li Y, Wang PH, Meng XM, He JG. | 11/13/2021 |
| CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features. | CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features.
Williams EA, Montesion M, Alexander BM, Ramkissoon SH, Elvin JA, Ross JS, Williams KJ, Glomski K, Bledsoe JR, Tse JY, Mochel MC., Free PMC Article | 10/23/2021 |
| TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination. | TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.
Zhu G, Herlyn M, Yang X., Free PMC Article | 10/16/2021 |
| CYLD-mutant cylindroma-like basaloid carcinoma of the anus: a genetically and morphologically distinct class of HPV-related anal carcinoma. | CYLD-mutant cylindroma-like basaloid carcinoma of the anus: a genetically and morphologically distinct class of HPV-related anal carcinoma.
Williams EA, Montesion M, Sharaf R, Corines J, Patel PJ, Gillespie BJ, Pavlick DC, Sokol ES, Alexander BM, Williams KJ, Elvin JA, Ross JS, Ramkissoon SH, Hemmerich AC, Tse JY, Mochel MC., Free PMC Article | 10/16/2021 |