| Immunoglobulin heavy constant gamma 1 silencing decreases tonicity-responsive enhancer-binding protein expression to alleviate diabetic nephropathy. | Immunoglobulin heavy constant gamma 1 silencing decreases tonicity-responsive enhancer-binding protein expression to alleviate diabetic nephropathy.
Hu Q, Yang Q, Gao H, Tian J, Che G., Free PMC Article | 05/8/2024 |
| In multiple sclerosis patients versus controls, IgG1 glycosylation patterns were altered in CSF, but not in serum. | Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.
Wuhrer M, Selman MH, McDonnell LA, Kümpfel T, Derfuss T, Khademi M, Olsson T, Hohlfeld R, Meinl E, Krumbholz M., Free PMC Article | 09/17/2016 |
| Altogether, these results support further evaluation of the SEB multiple B-cell epitope-vaccine to address MRSA infection in humans. | Multiple B-cell epitope vaccine induces a Staphylococcus enterotoxin B-specific IgG1 protective response against MRSA infection.
Zhao Z, Sun HQ, Wei SS, Li B, Feng Q, Zhu J, Zeng H, Zou QM, Wu C., Free PMC Article | 07/2/2016 |
| functional synergy between Flt3 and IL-4R signaling is critical for Stat-mediated regulation of sterile gamma1 germ-line transcripts and CSR to IgG1 | Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination.
Svensson MN, Andersson KM, Wasén C, Erlandsson MC, Nurkkala-Karlsson M, Jonsson IM, Brisslert M, Bemark M, Bokarewa MI., Free PMC Article | 04/9/2016 |
| IgG1 deficiency leads to increased severity of experimental autoimmune myasthenia gravis. | IgG1 deficiency exacerbates experimental autoimmune myasthenia gravis in BALB/c mice.
Huda R, Strait RT, Tüzün E, Finkelman FD, Christadoss P., Free PMC Article | 06/20/2015 |
| Ig isotypes that poorly activate effector mechanisms may be useful for inhibiting immune complex immunopathology | IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.
Strait RT, Posgai MT, Mahler A, Barasa N, Jacob CO, Köhl J, Ehlers M, Stringer K, Shanmukhappa SK, Witte D, Hossain MM, Khodoun M, Herr AB, Finkelman FD., Free PMC Article | 02/14/2015 |
| These results suggest that through activation of Th2-type cells, anti-MuSK immunity promotes production of IL-4, which in turn activates anti-MuSK IgG1, the mouse analog of human IgG4 | Preferential production of IgG1, IL-4 and IL-10 in MuSK-immunized mice.
Ulusoy C, Kim E, Tüzün E, Huda R, Yılmaz V, Poulas K, Trakas N, Skriapa L, Niarchos A, Strait RT, Finkelman FD, Turan S, Zisimopoulou P, Tzartos S, Saruhan-Direskeneli G, Christadoss P. | 05/17/2014 |
| The cytoplasmic tail of IgG1 is strictly required for the surface expression of IgG1 when the expression of Iga/Igb heterodimer is down-regulated in B lymphoma. | IgG1 cytoplasmic tail is essential for cell surface expression in Igβ down-regulated cells.
Todo K, Koga O, Nishikawa M, Hikida M. | 05/10/2014 |
| The anti-inflammatory activity of IgG1 is mediated by Fc galactosylation and association with FcgammaRIIB and dectin-1. | Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.
Karsten CM, Pandey MK, Figge J, Kilchenstein R, Taylor PR, Rosas M, McDonald JU, Orr SJ, Berger M, Petzold D, Blanchard V, Winkler A, Hess C, Reid DM, Majoul IV, Strait RT, Harris NL, Köhl G, Wex E, Ludwig R, Zillikens D, Nimmerjahn F, Finkelman FD, Brown GD, Ehlers M, Köhl J., Free PMC Article | 11/17/2012 |
| Bindings of albumin and IgG to neonatal Fc receptor were additive. | Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding.
Andersen JT, Daba MB, Berntzen G, Michaelsen TE, Sandlie I., Free PMC Article | 05/31/2010 |
| Determined the contact residues of the complex of the B domain of protein A and intact IgG, which has a molecular mass of 164 kDa and shows weak binding. | Determination of the interface of a large protein complex by transferred cross-saturation measurements.
Nakanishi T, Miyazawa M, Sakakura M, Terasawa H, Takahashi H, Shimada I. | 01/21/2010 |