| Progestin and adipoQ receptor 7 (PAQR7) mediate the anti-apoptotic effect of P4 on human granulosa cells and its deficiency reduces ovarian function in female mice. | Progestin and adipoQ receptor 7 (PAQR7) mediate the anti-apoptotic effect of P4 on human granulosa cells and its deficiency reduces ovarian function in female mice.
Li J, Liu Y, He J, Wu Z, Wang F, Huang J, Zheng L, Luo T., Free PMC Article | 03/11/2024 |
| Membrane progesterone receptors on the cell membrane: A review highlighting potential export motifs in mPRalpha regulating its trafficking to the cell surface. | Membrane progesterone receptors on the cell membrane: A review highlighting potential export motifs in mPRα regulating its trafficking to the cell surface.
Thomas P, Pang Y, Kelder J. | 10/12/2023 |
| Progesterone exerts a neuroprotective action in a Parkinson's disease human cell model through membrane progesterone receptor alpha (mPRalpha/PAQR7). | Progesterone exerts a neuroprotective action in a Parkinson's disease human cell model through membrane progesterone receptor α (mPRα/PAQR7).
Castelnovo LF, Thomas P., Free PMC Article | 03/31/2023 |
| Membrane Progesterone Receptor alpha (mPRalpha/PAQR7) Promotes Survival and Neurite Outgrowth of Human Neuronal Cells by a Direct Action and Through Schwann Cell-like Stem Cells. | Membrane Progesterone Receptor α (mPRα/PAQR7) Promotes Survival and Neurite Outgrowth of Human Neuronal Cells by a Direct Action and Through Schwann Cell-like Stem Cells.
Castelnovo LF, Thomas P. | 10/29/2022 |
| Establishment of a steroid binding assay for membrane progesterone receptor alpha (PAQR7) by using graphene quantum dots (GQDs). | Establishment of a steroid binding assay for membrane progesterone receptor alpha (PAQR7) by using graphene quantum dots (GQDs).
Jyoti MMS, Rana MR, Ali MH, Tokumoto T. | 02/12/2022 |
| Membrane progesterone receptor alpha (mPRalpha/PAQR7) promotes migration, proliferation and BDNF release in human Schwann cell-like differentiated adipose stem cells. | Membrane progesterone receptor α (mPRα/PAQR7) promotes migration, proliferation and BDNF release in human Schwann cell-like differentiated adipose stem cells.
Castelnovo LF, Thomas P. | 12/11/2021 |
| The results suggest that progesterone induces vascular smooth muscle cell relaxation by reducing cellular calcium levels through mPRalpha-induced alterations in multiple signaling pathways. | Role of mPRα (PAQR7) in progesterone-induced Ca2+ decrease in human vascular smooth muscle cells.
Pang Y, Thomas P. | 06/20/2020 |
| Utilizing both genetic and pharmacologic approaches, the authors establish that sex steroid effects on human melanin synthesis are mediated by the membrane-bound, steroid hormone receptors G protein-coupled estrogen receptor (GPER), and progestin and adipoQ receptor 7 (PAQR7). | Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors.
Natale CA, Duperret EK, Zhang J, Sadeghi R, Dahal A, O'Brien KT, Cookson R, Winkler JD, Ridky TW., Free PMC Article | 12/2/2017 |
| The effects of progesterone treatment on the expression levels of progesterone receptor membrane component 1 (PGRMC1), plasminogen activator inhibitor 1 RNA-binding protein (PAIRBP1), and progestin and adipoQ receptor 7 (PAQR7) on both mRNA and protein levels were investigated in spheroids derived from human glioma cell lines U-87 MG and LN-229. | Expression of Progesterone Receptor Membrane Component 1 (PGRMC1), Progestin and AdipoQ Receptor 7 (PAQPR7), and Plasminogen Activator Inhibitor 1 RNA-Binding Protein (PAIRBP1) in Glioma Spheroids In Vitro.
Hlavaty J, Ertl R, Miller I, Gabriel C., Free PMC Article | 03/27/2017 |
| Data show abundant mPRalpha (PAQR7), mPRbeta (PAQR8), and mPRgamma (PAQR5), but not classical nuclear PR (A or B isoforms) mRNA expression and mPRalpha protein expression in a panel of commonly used ovarian cancer cell lines. | Expression of membrane progesterone receptors (mPR/PAQR) in ovarian cancer cells: implications for progesterone-induced signaling events.
Charles NJ, Thomas P, Lange CA., Free PMC Article | 12/24/2011 |
| mPRalpha is an intermediary in progestin stimulation of sperm motility in humans by a mechanism involving G-protein activation | Progestin functions in vertebrate gametes mediated by membrane progestin receptors (mPRs): Identification of mPRalpha on human sperm and its association with sperm motility.
Thomas P, Tubbs C, Garry VF. | 01/21/2010 |
| Heterologous expression of MPRA in yeast confirms its ability to function as a membrane progesterone receptor. | Heterologous expression of human mPRalpha, mPRbeta and mPRgamma in yeast confirms their ability to function as membrane progesterone receptors.
Smith JL, Kupchak BR, Garitaonandia I, Hoang LK, Maina AS, Regalla LM, Lyons TJ., Free PMC Article | 01/21/2010 |
| cDNAs for the mPR alpha subtypes from spotted seatrout (st-mPRalpha) and humans (hu-mPRalpha) encode progestin receptors that display many functional characteristics of G protein-coupled receptors. | Steroid and G protein binding characteristics of the seatrout and human progestin membrane receptor alpha subtypes and their evolutionary origins.
Thomas P, Pang Y, Dong J, Groenen P, Kelder J, de Vlieg J, Zhu Y, Tubbs C. | 01/21/2010 |