| Omentin-1 inhibits the development of benign prostatic hyperplasia by attenuating local inflammation. | Omentin-1 inhibits the development of benign prostatic hyperplasia by attenuating local inflammation.
Wang YY, Zhu GQ, Xia K, Zeng HB, He YH, Xie H, Wang ZX, Xu R., Free PMC Article | 07/15/2024 |
| The potential role of omentin-1 in obesity-related metabolic dysfunction-associated steatotic liver disease: evidence from translational studies. | The potential role of omentin-1 in obesity-related metabolic dysfunction-associated steatotic liver disease: evidence from translational studies.
Salvoza N, Giraudi P, Gazzin S, Bonazza D, Palmisano S, de Manzini N, Zanconati F, Raseni A, Sirianni F, Tiribelli C, Rosso N., Free PMC Article | 04/2/2024 |
| Activation of ITLN-1 attenuates oxidative stress injury via activating SIRT1/PGC1-alpha signaling in neuroblastoma cells. | Activation of ITLN-1 attenuates oxidative stress injury via activating SIRT1/PGC1-α signaling in neuroblastoma cells.
Niu X, Di W, Zhang Z, Li N, Qiu Z, Shi W, Lei W, Tang J, Yang Y, Xu B, Tian Y. | 02/5/2024 |
| Omentin-1 drives cardiomyocyte cell cycle arrest and metabolic maturation by interacting with BMP7. | Omentin-1 drives cardiomyocyte cell cycle arrest and metabolic maturation by interacting with BMP7.
Yang H, Song S, Li J, Li Y, Feng J, Sun Q, Qiu X, Chen Z, Bai X, Liu X, Lian H, Liu L, Bai Y, Zhang G, Nie Y., Free PMC Article | 06/23/2023 |
| Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila. | Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.
Matute JD, Duan J, Flak MB, Griebel P, Tascon-Arcila JA, Doms S, Hanley T, Antanaviciute A, Gundrum J, Mark Welch JL, Sit B, Abtahi S, Fuhler GM, Grootjans J, Tran F, Stengel ST, White JR, Krupka N, Haller D, Clare S, Lawley TD, Kaser A, Simmons A, Glickman JN, Bry L, Rosenstiel P, Borisy G, Waldor MK, Baines JF, Turner JR, Blumberg RS., Free PMC Article | 12/3/2022 |
| Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy. | Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy.
Hu J, Liu T, Fu F, Cui Z, Lai Q, Zhang Y, Yu B, Liu F, Kou J, Li F., Free PMC Article | 10/8/2022 |
| Characterization of an intelectin-1 (Itln1) knockout mouse model. | Characterization of an intelectin-1 (Itln1) knockout mouse model.
Nonnecke EB, Castillo PA, Akahoshi DT, Goley SM, Bevins CL, Lönnerdal B., Free PMC Article | 09/17/2022 |
| Intelectin1 ameliorates macrophage activation via inhibiting the nuclear factor kappa B pathway. | Intelectin1 ameliorates macrophage activation via inhibiting the nuclear factor kappa B pathway.
Kobayashi H, Uchimura K, Ishii T, Takahashi K, Mori K, Tsuchiya K, Furuya F. | 06/11/2022 |
| ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma. | ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma.
Chen L, Jin XH, Luo J, Duan JL, Cai MY, Chen JW, Feng ZH, Guo AM, Wang FW, Xie D. | 01/29/2022 |
| Deficiency of Omentin-1 leads to delayed fracture healing through excessive inflammation and reduced CD31(hi)Emcn(hi) vessels. | Deficiency of Omentin-1 leads to delayed fracture healing through excessive inflammation and reduced CD31(hi)Emcn(hi) vessels.
Feng SK, Chen TH, Li HM, Cao J, Liu DB, Rao SS, Liu JH, Zhang Y, Wang ZX, Li YY, Tan YJ, Liu YW, Hong CG, Yan ZQ, Chen ML, Wang YY, Yin H, Jin L, Xie H, Wang ZG, Zhou Y. | 01/15/2022 |
| these studies conclude that ITLN contributes to allergen-induced Il-25, Il-33, and Tslp expression in asthma and atopic dermatitis | Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis.
Yi L, Cheng D, Zhang K, Huo X, Mo Y, Shi H, Di H, Zou Y, Zhang H, Zhao J, Xu Y, Erle DJ, Zhen G., Free PMC Article | 06/2/2018 |
| Omentin protects against lipopysaccharides-induced acute respiratory distress syndrome through suppressing pulmonary inflammation and promoting endothelial barrier via an Akt/NOS3-dependent mechanism. | Omentin protects against LPS-induced ARDS through suppressing pulmonary inflammation and promoting endothelial barrier via an Akt/eNOS-dependent mechanism.
Qi D, Tang X, He J, Wang D, Zhao Y, Deng W, Deng X, Zhou G, Xia J, Zhong X, Pu S., Free PMC Article | 10/28/2017 |
| omentin reduces the development of atherosclerosis by reducing inflammatory response of macrophages through the Akt-dependent mechanisms | Omentin attenuates atherosclerotic lesion formation in apolipoprotein E-deficient mice.
Hiramatsu-Ito M, Shibata R, Ohashi K, Uemura Y, Kanemura N, Kambara T, Enomoto T, Yuasa D, Matsuo K, Ito M, Hayakawa S, Ogawa H, Otaka N, Kihara S, Murohara T, Ouchi N. | 12/31/2016 |
| miR-584 contributes to the post-transcriptional expression of lactoferrin receptor during the perinatal period. | miR-584 mediates post-transcriptional expression of lactoferrin receptor in Caco-2 cells and in mouse small intestine during the perinatal period.
Liao Y, Lönnerdal B. | 10/23/2010 |
| Intelectin, a molecule expressed by airway epithelial cells and upregulated in asthma, is required for IL-13-induced MCP-1 and -3 production in mouse lung epithelial cells and contributes to allergic airway inflammation. | Intelectin is required for IL-13-induced monocyte chemotactic protein-1 and -3 expression in lung epithelial cells and promotes allergic airway inflammation.
Gu N, Kang G, Jin C, Xu Y, Zhang Z, Erle DJ, Zhen G., Free PMC Article | 03/22/2010 |
| intelectin is a host defense lectin that assists phagocytic clearance of microorganisms. | Capture of heat-killed Mycobacterium bovis bacillus Calmette-Guérin by intelectin-1 deposited on cell surfaces.
Tsuji S, Yamashita M, Hoffman DR, Nishiyama A, Shinohara T, Ohtsu T, Shibata Y., Free PMC Article | 01/21/2010 |
| These findings support the notion that until the development-dependent expression of DMT1 in the intestine is induced, mouse LfR may serve as an alternative iron uptake pathway. | Ontogenic changes in lactoferrin receptor and DMT1 in mouse small intestine: implications for iron absorption during early life.
Lopez V, Suzuki YA, Lönnerdal B. | 01/21/2010 |
| Strategic localization of intelectin at the enterocyte brush border suggests that trimeric intelectin serves as an organizer and stabilizer of the brush border membrane. | Intelectin: a novel lipid raft-associated protein in the enterocyte brush border.
Wrackmeyer U, Hansen GH, Seya T, Danielsen EM. | 01/21/2010 |
| Data show that the mouse lactoferrin receptor (MLfR) functions as a receptor for MLf, is expressed and localized in various tissues, and may be involved in the indispensable function of MLf during early embryonic development. | Baculovirus expression of mouse lactoferrin receptor and tissue distribution in the mouse.
Suzuki YA, Lönnerdal B. | 01/21/2010 |