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    Jun jun proto-oncogene [ Mus musculus (house mouse) ]

    Gene ID: 16476, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Jun-activated SOCS1 enhances ubiquitination and degradation of CCAAT/enhancer-binding protein beta to ameliorate cerebral ischaemia/reperfusion injury.

    Jun-activated SOCS1 enhances ubiquitination and degradation of CCAAT/enhancer-binding protein β to ameliorate cerebral ischaemia/reperfusion injury.
    He C, Wang T, Han Y, Zuo C, Wang G.

    10/10/2024
    The Role of Activator Protein-1 Complex in Diabetes-Associated Atherosclerosis: Insights From Single-Cell RNA Sequencing.

    The Role of Activator Protein-1 Complex in Diabetes-Associated Atherosclerosis: Insights From Single-Cell RNA Sequencing.
    Khan AW, Aziz M, Sourris KC, Lee MKS, Dai A, Watson AMD, Maxwell S, Sharma A, Zhou Y, Cooper ME, Calkin AC, Murphy AJ, Baratchi S, Jandeleit-Dahm KAM.

    10/1/2024
    Hsp90aa1/JUN/Ccl2 regulatory axis mediates migration and differentiation of NSPCs, promoting the onset and progression of early post-ischemic stroke epilepsy.

    Hsp90aa1/JUN/Ccl2 regulatory axis mediates migration and differentiation of NSPCs, promoting the onset and progression of early post-ischemic stroke epilepsy.
    Hu S, Tang Y, Li X, Li W, Zeng Y, Jiang M, Chen R, Zheng P, Yang L, Song Z, Xie D, Chen Y, Yuan Y.

    09/18/2024
    Knockdown of BUB1B Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer by Regulating the JNK/c-Jun Signaling Pathway.

    Knockdown of BUB1B Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer by Regulating the JNK/c-Jun Signaling Pathway.
    Zeng Q, Zhang S, He L, Fu Q, Liao L, Chen L, Ding X.

    04/17/2024
    Gasdermin E promotes translocation of p65 and c-jun into nucleus in keratinocytes for progression of psoriatic skin inflammation.

    Gasdermin E promotes translocation of p65 and c-jun into nucleus in keratinocytes for progression of psoriatic skin inflammation.
    Long F, Wei X, Chen Y, Li M, Lian N, Yu S, Chen S, Yang Y, Li M, Gu H, Chen X., Free PMC Article

    03/14/2024
    The role of c-Jun for beating cardiomycyte formation in prepared embryonic body.

    The role of c-Jun for beating cardiomycyte formation in prepared embryonic body.
    Su L, Zhang G, Jiang L, Chi C, Bai B, Kang K., Free PMC Article

    01/3/2024
    BMAL1 modulates senescence programming via AP-1.

    BMAL1 modulates senescence programming via AP-1.
    Jachim SK, Zhong J, Ordog T, Lee JH, Bhagwate AV, Nagaraj NK, Westendorf JJ, Passos JF, Matveyenko AV, LeBrasseur NK., Free PMC Article

    10/24/2023
    AP-1 is a regulatory transcription factor of inflammaging in the murine kidney and liver.

    AP-1 is a regulatory transcription factor of inflammaging in the murine kidney and liver.
    Yu X, Wang Y, Song Y, Gao X, Deng H., Free PMC Article

    09/12/2023
    YAP promotes AP-1 expression in tubular epithelial cells in the kidney.

    YAP promotes AP-1 expression in tubular epithelial cells in the kidney.
    Liu Y, Xu C, Li J, Zhang Y, Wang X, Wang Y, Qin J, Zheng Z, Xia Y.

    06/18/2023
    JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy.

    JNK-JUN-NCOA4 axis contributes to chondrocyte ferroptosis and aggravates osteoarthritis via ferritinophagy.
    Sun K, Hou L, Guo Z, Wang G, Guo J, Xu J, Zhang X, Guo F.

    05/23/2023
    Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.

    Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
    Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J.

    05/17/2023
    Screening of ferroptosis-related genes in sepsis-induced liver failure and analysis of immune correlation.

    Screening of ferroptosis-related genes in sepsis-induced liver failure and analysis of immune correlation.
    Chen Q, Liu L, Ni S., Free PMC Article

    02/14/2023
    Hepatocytic AP-1 and STAT3 contribute to chemotaxis in alphanaphthylisothiocyanate-induced cholestatic liver injury.

    Hepatocytic AP-1 and STAT3 contribute to chemotaxis in alphanaphthylisothiocyanate-induced cholestatic liver injury.
    Luo Y, Kang J, Luo J, Yan Z, Li S, Lu Z, Song Y, Zhang X, Yang J, Liu A.

    01/14/2023
    Developmental genome-wide occupancy analysis of bZIP transcription factor NRL uncovers the role of c-Jun in early differentiation of rod photoreceptors in the mammalian retina.

    Developmental genome-wide occupancy analysis of bZIP transcription factor NRL uncovers the role of c-Jun in early differentiation of rod photoreceptors in the mammalian retina.
    Liang X, Brooks MJ, Swaroop A., Free PMC Article

    11/26/2022
    PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development.

    PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development.
    Zhao X, Bartholdy B, Yamamoto Y, Evans EK, Alberich-Jordà M, Staber PB, Benoukraf T, Zhang P, Zhang J, Trinh BQ, Crispino JD, Hoang T, Bassal MA, Tenen DG., Free PMC Article

    10/1/2022
    IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis.

    IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis.
    Fujita H, Fujita T, Fujii H., Free PMC Article

    05/21/2022
    Data suggest that Sf1 and c-jun interact and cooperate to activate the Fdx1 promoter in MA-10 (tumorigenic cell line) and TM3 (non-tumorigenic cell line) Leydig cells; such activation requires different regulatory elements located between -124 and -306 bp of Fdx1 promoter and involves recruitment of Sf1 to this region.

    Transcription factors SF1 and cJUN cooperate to activate the Fdx1 promoter in MA-10 Leydig cells.
    Roumaud P, Rwigemera A, Martin LJ.

    03/30/2022
    A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair.

    A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair.
    Velasco-Aviles S, Patel N, Casillas-Bajo A, Frutos-Rincón L, Velasco E, Gallar J, Arthur-Farraj P, Gomez-Sanchez JA, Cabedo H., Free PMC Article

    02/26/2022
    KCa3.1 inhibition-induced activation of the JNK/c-Jun signaling pathway enhances IL-10 expression in peripherally-induced regulatory T cells.

    K(Ca)3.1 inhibition-induced activation of the JNK/c-Jun signaling pathway enhances IL-10 expression in peripherally-induced regulatory T cells.
    Matsui M, Kajikuri J, Endo K, Kito H, Ohya S.

    02/12/2022
    Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun.

    Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun.
    Wagstaff LJ, Gomez-Sanchez JA, Fazal SV, Otto GW, Kilpatrick AM, Michael K, Wong LYN, Ma KH, Turmaine M, Svaren J, Gordon T, Arthur-Farraj P, Velasco-Aviles S, Cabedo H, Benito C, Mirsky R, Jessen KR., Free PMC Article

    02/5/2022
    Long-Term Suppression of c-Jun and nNOS Preserves Ultrastructural Features of Lower Motor Neurons and Forelimb Function after Brachial Plexus Roots Avulsion.

    Long-Term Suppression of c-Jun and nNOS Preserves Ultrastructural Features of Lower Motor Neurons and Forelimb Function after Brachial Plexus Roots Avulsion.
    Zilundu PLM, Xu X, Liaquat Z, Wang Y, Zhong K, Fu R, Zhou L., Free PMC Article

    10/30/2021
    Psoriatic skin inflammation is promoted by c-Jun/AP-1-dependent CCL2 and IL-23 expression in dendritic cells.

    Psoriatic skin inflammation is promoted by c-Jun/AP-1-dependent CCL2 and IL-23 expression in dendritic cells.
    Novoszel P, Holcmann M, Stulnig G, De Sa Fernandes C, Zyulina V, Borek I, Linder M, Bogusch A, Drobits B, Bauer T, Tam-Amersdorfer C, Brunner PM, Stary G, Bakiri L, Wagner EF, Strobl H, Sibilia M., Free PMC Article

    10/30/2021
    In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun.

    In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun.
    Riedel M, Berthelsen MF, Cai H, Haldrup J, Borre M, Paludan SR, Hager H, Vendelbo MH, Wagner EF, Bakiri L, Thomsen MK., Free PMC Article

    10/23/2021
    beta-Asarone suppresses TNF-alpha expression through DNA methylation and c-Jun-mediated transcription modulation in scratch-injured neuronal cells.

    β-Asarone suppresses TNF-α expression through DNA methylation and c-Jun-mediated transcription modulation in scratch-injured neuronal cells.
    Yi M, Wang D, Chen Y, Xu X, Dai X.

    09/4/2021
    Amniotic fluid mesenchymal stem cells repair mouse corneal cold injury by promoting mRNA N4-acetylcytidine modification and ETV4/JUN/CCND2 signal axis activation.

    Amniotic fluid mesenchymal stem cells repair mouse corneal cold injury by promoting mRNA N4-acetylcytidine modification and ETV4/JUN/CCND2 signal axis activation.
    Fei X, Cai Y, Lin F, Huang Y, Liu T, Liu Y., Free PMC Article

    07/3/2021
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