The effects of sildenafil citrate on urinary podocin and nephrin mRNA expression in an L-NAME model of pre-eclampsia. | The effects of sildenafil citrate on urinary podocin and nephrin mRNA expression in an L-NAME model of pre-eclampsia. Baijnath S, Murugesan S, Mackraj I, Gathiram P, Moodley J. | 02/18/2017 |
These findings suggest that candesartan can prevent cisplatin-induced testicular damage by regulating expression patterns of the nephrin-podocin complex in the testes. | Candesartan Mediated Amelioration of Cisplatin-Induced Testicular Damage Is Associated with Alterations in Expression Patterns of Nephrin and Podocin. Enatsu N, Miyake H, Chiba K, Fujisawa M., Free PMC Article | 08/20/2016 |
translocation of podocin by endocytosis could be a key traffic event of critical podocyte injury and that the podocin gap could indicate the prognosis of IgA nephropathy. | Podocin is translocated to cytoplasm in puromycin aminonucleoside nephrosis rats and in poor-prognosis patients with IgA nephropathy. Fukuda H, Hidaka T, Takagi-Akiba M, Ichimura K, Oliva Trejo JA, Sasaki Y, Wang J, Sakai T, Asanuma K, Tomino Y., Free PMC Article | 01/30/2016 |
Resveratrol alleviated dyslipidemia and renal damage induced by high-fat diet also reduced TNF-alpha and MCP-1 levels, and reduced expressions of nephrin and podocin. | Resveratrol increases nephrin and podocin expression and alleviates renal damage in rats fed a high-fat diet. Pan QR, Ren YL, Zhu JJ, Hu YJ, Zheng JS, Fan H, Xu Y, Wang G, Liu WX., Free PMC Article | 02/28/2015 |
ATP evokes activation of TRPC6 channels in podocytes through P2Y receptors, podocin, and generation of reactive oxygen species. | ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species. Roshanravan H, Dryer SE. | 06/21/2014 |
Huaiqihuang Granule can up-regulate the expressions of nephrin and podocin in renal tissues of rats with adriamycin-induced nephrosis. | [Effects of Chinese herbal medicine Huaiqihuang Granule on nephrin and podocin expressions in renal tissues of rats with adriamycin-induced nephrosis]. Sun W, Zhu Z, Yu J, Wang YH, Xiong M, Gao X, Zhao ZH, Liu XG. | 03/17/2012 |
Podocin may serve as scaffold that links tight junction proteins to actin cytoskeleton in nephrotic foot processes. | Podocin participates in the assembly of tight junctions between foot processes in nephrotic podocytes. Shono A, Tsukaguchi H, Yaoita E, Nameta M, Kurihara H, Qin XS, Yamamoto T, Doi T. | 01/21/2010 |
variants in NPHS2 promoter is associated with nephrotic syndrome | Rare functional variants of podocin (NPHS2) promoter in patients with nephrotic syndrome. Oleggini R, Bertelli R, Di Donato A, Di Duca M, Caridi G, Sanna-Cherchi S, Scolari F, Murer L, Allegri L, Coppo R, Emma F, Camussi G, Perfumo F, Ghiggeri GM., Free PMC Article | 01/21/2010 |
podocin is one of critical components of slit diaphragm for maintaining barrier function of glomerular capillary wall | Cloning of rat homologue of podocin: expression in proteinuric states and in developing glomeruli. Kawachi H, Koike H, Kurihara H, Sakai T, Shimizu F. | 01/21/2010 |
Fyn phosphorylates the cytoplasmic domain of nephrin on tyrosine, leading to enhanced association with podocin and downstream signaling of nephrin. | SRC-family kinase Fyn phosphorylates the cytoplasmic domain of nephrin and modulates its interaction with podocin. Li H, Lemay S, Aoudjit L, Kawachi H, Takano T. | 01/21/2010 |
Downregulation of podocin in induced Minimal change-like nephropathy. | Overexpression of interleukin-13 induces minimal-change-like nephropathy in rats. Lai KW, Wei CL, Tan LK, Tan PH, Chiang GS, Lee CG, Jordan SC, Yap HK. | 01/21/2010 |