PEG10 amplification at 7q21.3 potentiates large-cell transformation in cutaneous T-cell lymphoma. | PEG10 amplification at 7q21.3 potentiates large-cell transformation in cutaneous T-cell lymphoma. Liu F, Gao Y, Xu B, Xiong S, Yi S, Sun J, Chen Z, Liu X, Li Y, Lin Y, Wen Y, Qin Y, Yang S, Li H, Tejasvi T, Tsoi L, Tu P, Ren X, Wang Y., Free PMC Article | 03/12/2022 |
PEG10 viral aspartic protease domain is essential for the maintenance of fetal capillary structure in the mouse placenta. | PEG10 viral aspartic protease domain is essential for the maintenance of fetal capillary structure in the mouse placenta. Shiura H, Ono R, Tachibana S, Kohda T, Kaneko-Ishino T, Ishino F., Free PMC Article | 12/4/2021 |
Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery. | Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery. Segel M, Lash B, Song J, Ladha A, Liu CC, Jin X, Mekhedov SL, Macrae RK, Koonin EV, Zhang F., Free PMC Article | 08/28/2021 |
LncRNA PEG10 aggravates cardiac hypertrophy through regulating HOXA9. | LncRNA PEG10 aggravates cardiac hypertrophy through regulating HOXA9. Wen ZQ, Li SH, Shui X, Tang LL, Zheng JR, Chen L. | 09/19/2020 |
Expression of Hbegf was reduced in PEG10-deficient trophoblast stem cells (TSCs) suggesting that PEG10 might bind to and stabilize RNAs that are critical for normal placental development | The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification. Abed M, Verschueren E, Budayeva H, Liu P, Kirkpatrick DS, Reja R, Kummerfeld SK, Webster JD, Gierke S, Reichelt M, Anderson KR, Newman RJ, Roose-Girma M, Modrusan Z, Pektas H, Maltepe E, Newton K, Dixit VM., Free PMC Article | 12/21/2019 |
Loss of DNA methylation at the Peg10 imprinted gDMD associated with decreased embryonic viability and decreased labyrinthine volume. | Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development. Koppes E, Himes KP, Chaillet JR., Free PMC Article | 05/21/2016 |
Knockdown of Syncytin-A demonstrated a functional regulation of cell-cell fusion, where knockdown of Peg10 showed no involvement in cell fusion | Regulation of murine placentogenesis by the retroviral genes Syncytin-A, Syncytin-B and Peg10. Henke C, Ruebner M, Faschingbauer F, Stolt CC, Schaefer N, Lang N, Beckmann MW, Strissel PL, Strick R. | 11/16/2013 |
Characterization of a RNA pseudoknot as a frameshift signal for Edr programmed -1 ribosomal frameshifting. | Characterization of the frameshift signal of Edr, a mammalian example of programmed -1 ribosomal frameshifting. Manktelow E, Shigemoto K, Brierley I, Manktelow E, Shigemoto K, Brierley I., Free PMC Articles: PMC1065257, PMC1065257 | 10/18/2012 |
It is a retrotransposon-derived imprinted gene and plays a essential role in placental formation.(review) | [Origin of viviparity and genomic imprinting in mammals: a view from a retrotransposon-derived imprinted gene PEG10]. Kaneko-Ishino T, Suzuki S, Ono R, Ishino F. | 01/1/2011 |
Peg10 gene is imprinted, with preferential expression from the paternal allele, and its deletion results in early embryonic lethality. | Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. Ono R, Nakamura K, Inoue K, Naruse M, Usami T, Wakisaka-Saito N, Hino T, Suzuki-Migishima R, Ogonuki N, Miki H, Kohda T, Ogura A, Yokoyama M, Kaneko-Ishino T, Ishino F. | 12/8/2010 |
the ORF1-2 protein of PEG10, synthesized utilizing the most efficient -1 frameshift mechanism yet documented in vivo, will have an essential function that is intrinsic to the importance of PEG10 in mammals | Mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues. Clark MB, Jänicke M, Gottesbühren U, Kleffmann T, Legge M, Poole ES, Tate WP. | 01/21/2010 |
These findings strongly indicate that peg10 plays a crucial role at the immediate early stage of adipocyte differentiation. | peg10, an imprinted gene, plays a crucial role in adipocyte differentiation. Hishida T, Naito K, Osada S, Nishizuka M, Imagawa M. | 01/21/2010 |
Results indicate that the induction of the imprinted gene paternally expressed 10 (PEG10) may play an important role during liver regeneration or carcinogenesis of the hepatocyte. | Overexpression of a novel imprinted gene, PEG10, in human hepatocellular carcinoma and in regenerating mouse livers. Tsou AP, Chuang YC, Su JY, Yang CW, Liao YL, Liu WK, Chiu JH, Chou CK. | 01/21/2010 |
Programmed -1 ribosomal frameshifting in mouse and human Peg10 genes. | Characterization of the frameshift signal of Edr, a mammalian example of programmed -1 ribosomal frameshifting. Manktelow E, Shigemoto K, Brierley I, Manktelow E, Shigemoto K, Brierley I., Free PMC Articles: PMC1065257, PMC1065257 | 08/16/2007 |