| Regulation of RHOV signaling by interaction with SH3 domain-containing adaptor proteins and phosphorylation by PKA. | Regulation of RHOV signaling by interaction with SH3 domain-containing adaptor proteins and phosphorylation by PKA.
Harlin EW, Ito T, Nakano S, Morikawa K, Sato K, Nishikawa M, Nakamura K, Nagaoka H, Nagase T, Ueda H. | 08/7/2024 |
| Prognostic significance of the rho GTPase RHOV and its role in tumor immune cell infiltration: a comprehensive pan-cancer analysis. | Prognostic significance of the rho GTPase RHOV and its role in tumor immune cell infiltration: a comprehensive pan-cancer analysis.
Qin Q, Peng B., Free PMC Article | 11/13/2023 |
| In vivo CRISPR screens identify RhoV as a pro-metastasis factor of triple-negative breast cancer. | In vivo CRISPR screens identify RhoV as a pro-metastasis factor of triple-negative breast cancer.
Jin ML, Gong Y, Ji P, Hu X, Shao ZM., Free PMC Article | 06/7/2023 |
| RHOV promotes lung adenocarcinoma cell growth and metastasis through JNK/c-Jun pathway. | RHOV promotes lung adenocarcinoma cell growth and metastasis through JNK/c-Jun pathway.
Zhang D, Jiang Q, Ge X, Shi Y, Ye T, Mi Y, Xie T, Li Q, Ye Q., Free PMC Article | 03/19/2022 |
| A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry. | A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry.
Luu AP, Yao Z, Ramachandran S, Azzopardi SA, Miles LA, Schneider WM, Hoffmann HH, Bozzacco L, Garcia G Jr, Gong D, Damoiseaux R, Tang H, Morizono K, Rudin CM, Sun R, Arumugaswami V, Poirier JT, MacDonald MR, Rice CM, Li MMH., Free PMC Article | 02/12/2022 |
| Our results suggest that the effector domain of RhoV mediates its binding to Pak1, complementing the current view of the molecular basics of RhoV binding to effectors of the Pak family. | [Mutations in the Effector Domain of RhoV GTPase Impair Its Binding to Pak1 Protein Kinase].
Korobko IV, Shepelev MV. | 05/11/2019 |
| This review addresses the developmental roles of 2 GTPases of the Rho family, RhoV/Chp and RhoU/Wrch. | Atypical RhoV and RhoU GTPases control development of the neural crest.
Faure S, Fort P., Free PMC Article | 01/20/2018 |
| Authors propose that the RHOV gene could be validated as a diagnostic or prognostic marker for NSCLC, and that observed overexpression of RHOV might contribute to tumorigenesis. | The RHOV gene is overexpressed in human non-small cell lung cancer.
Shepelev MV, Korobko IV. | 06/14/2014 |
| CDC42 homologous protein does not enhance the level of Ser60 phosphorylation in Pak6. (RHO V protein) | Pak6 protein kinase is a novel effector of an atypical Rho family GTPase Chp/RhoV.
Shepelev MV, Korobko IV. | 06/9/2012 |
| Results demonstrate a novel mechanism of signal termination mediated by the Rho-family GTPases Chp and Cdc42, which results in ubiquitin-mediated degradation of one of their direct effectors, Pak1. | Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.
Weisz Hubsman M, Volinsky N, Manser E, Yablonski D, Aronheim A., Free PMC Article | 01/21/2010 |
| cloning and characterization of WRCH2 on human chromosome 15q15 | Molecular cloning and characterization of WRCH2 on human chromosome 15q15.
Katoh M. | 01/21/2010 |
| Data suggest that Chp is implicated in cell transformation, and the unique amino and carboxyl termini of Chp represent atypical mechanisms of regulation of Rho GTPase function. | Critical and distinct roles of amino- and carboxyl-terminal sequences in regulation of the biological activity of the Chp atypical Rho GTPase.
Chenette EJ, Abo A, Der CJ. | 01/21/2010 |